27 Myalgic Encephalomyelitis Clinical Trials in Indianapolis, IN (2026)

Q: Are there myalgic encephalomyelitis clinical trials in Indianapolis?

Yes, there are 27 myalgic encephalomyelitis clinical trials currently recruiting in Indianapolis, IN.

Q: How do I join a clinical trial in Indianapolis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you.

Q: Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Myalgic Encephalomyelitis Studies in Indianapolis

NCT00097292Recruiting

TrialNet Pathway to Prevention of T1D

Rationale: The accrual of data from the laboratory and from epidemiologic and prevention trials has improved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Gen...

Indianapolis, IN75,000 participantsUniversity of South Florida

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NCT03507257Recruiting

Longitudinal Early-onset Alzheimer's Disease Study Protocol

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) is a non-randomized, natural history, non-treatment study designed to look at disease progression in individuals with early onset cogniti...

Indianapolis, IN850 participantsIndiana University

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NCT00869817Recruiting

Dominantly Inherited Alzheimer Network (DIAN)

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation....

Indianapolis, IN700 participantsWashington University School of Medicine

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NCT05462106Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with...

Indianapolis, INPHASE1304 participantsAC Immune SA

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NCT06647498Recruiting

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

The purpose of this research study is to test the study drug, referred to as remternetug, to determine its effectiveness for the study treatment of asymptomatic (at risk) Alzheimer disease in individu...

Indianapolis, INPHASE2280 participantsWashington University School of Medicine

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NCT05552157Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

The purpose is to evaluate the biomarker effect, safety, and tolerability of investigational study drugs in participants who are known to have an Alzheimer's disease (AD)-causing mutation. Stage 1 wil...

Indianapolis, INPHASE2280 participantsWashington University School of Medicine

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NCT05797831Recruiting

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have achieved complete response or partial response on chemotherapy. The ...

Indianapolis, INPHASE2268 participantsKartos Therapeutics, Inc.

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NCT06752681Recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors

This is a Phase 1a/1b, open-label, dose escalation and expansion study to evaluate the safety and anti-tumor activity of DAY301, a PTK7-directed antibody-drug conjugate in participants with advanced o...

Indianapolis, INPHASE1254 participantsDay One Biopharmaceuticals, Inc.

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NCT05100342Recruiting

Prospective Validation of a Points Score System Predicting 30-day Survival

This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncology for palliative t...

Indianapolis, IN214 participantsIndiana University

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NCT07579702Recruiting

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

This multi-center, randomized, cross-over trial will evaluate the efficacy of the Omnipod 6 System compared with the Omnipod 5 System in individuals with type 1 or type 2 diabetes and suboptimal glyce...

Indianapolis, INNA200 participantsInsulet Corporation

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NCT06366464Recruiting

A Study of Pitolisant in Patients With Prader-Willi Syndrome

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The ...

Indianapolis, INPHASE3134 participantsHarmony Biosciences Management, Inc.

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NCT07401316Recruiting

Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors

This study will evaluate the utility of ctDNA detection in patients with high-risk stage I, stage II, and stage III germ cell tumor disease to develop a tool for post-treatment cancer cell detection....

Indianapolis, INNA130 participantsIndiana University

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NCT06414460Recruiting

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are to evaluate the safety and tolerability o...

Indianapolis, INPHASE1114 participantsInSilico Medicine Hong Kong Limited

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NCT06049680Recruiting

Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients

Evaluate the risk of developing EFAD and/or PNAC in adult and pediatric patients 1 month of age and older, who are anticipated to need 8 weeks or longer of parenteral nutrition treatment with SMOFlipi...

Indianapolis, INPHASE4100 participantsFresenius Kabi

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NCT06423430Recruiting

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjuncti...

Indianapolis, INNA100 participantsAbbott Medical Devices

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NCT07224321Recruiting

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to \<18 year...

Indianapolis, INPHASE2100 participantsMannkind Corporation

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NCT04817618Recruiting

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

The Primary Completion Date and Study Completion Date have been updated to reflect completion of the adolescent cohort, which has been added to the protocol. The study is designed as a multicenter, r...

Indianapolis, INPHASE398 participantsNovartis Pharmaceuticals

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NCT07332091Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-rel...

Indianapolis, INPHASE284 participantsCSL Behring

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NCT05231785Recruiting

A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-APP administered by intrathecal (IT) injec...

Indianapolis, INPHASE160 participantsAlnylam Pharmaceuticals

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NCT05573490Recruiting

Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study

The purpose of this study is to generate preliminary data on the benefit of computerized cognitive training and Tai Chi- Qi Gong training in participants with Early-Onset Alzheimer's Disease. It is hy...

Indianapolis, INNA60 participantsIndiana University

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NCT07446322Recruiting

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

This is an open-label, randomized, multicenter Phase 2 study to assess the efficacy and safety of FOLFIRI + bevacizumab + pelareorep vs. FOLFIRI + bevacizumab in patients with RAS-mutated, MSS mCRC wh...

Indianapolis, INPHASE260 participantsOncolytics Biotech

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NCT07096843Recruiting

A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy

To evaluate the safety and tolerability of three dose regimens of budoprutug in subjects with PMN...

Indianapolis, INPHASE245 participantsClimb Bio, Inc.

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NCT06582706Recruiting

Nicotinic Acid for the Treatment of Alzheimer's Disease

Increased dietary intake of niacin is correlated with reduced risk of Alzheimer's Disease and age-associated cognitive decline. The goal of this study is to collect data on the penetration of commerci...

Indianapolis, INPHASE130 participantsIndiana University

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NCT03266640Recruiting

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovi...

Indianapolis, INPHASE220 participantsNew York Medical College

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NCT06511544Recruiting

rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression

The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in a...

Indianapolis, INNA20 participantsIndiana University

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NCT05789056Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

To assess the safety, tolerability, and efficacy of QRX003 lotion (4%) when added to standard of care treatment regimen, including systemic therapy in subjects with Netherton syndrome...

Indianapolis, INPHASE220 participantsQuoin Pharmaceuticals

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NCT07538583Recruiting

Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

This is a multicenter, open-label study to evaluate the safety, tolerability, and efficacy of 4% QRX003 lotion applied twice daily (BID) for 12 weeks to Netherton syndrome (NS) diseased skin in all af...

Indianapolis, INPHASE216 participantsQuoin Pharmaceuticals

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About Myalgic Encephalomyelitis Clinical Trials in Indianapolis

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 27 myalgic encephalomyelitis clinical trials recruiting participants in Indianapolis, IN. These studies are seeking a combined 79,541 participants. Research is being sponsored by University of South Florida, Indiana University, Washington University School of Medicine and 16 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in Indianapolis — FAQ

Are there myalgic encephalomyelitis clinical trials in Indianapolis?

Yes, there are 27 myalgic encephalomyelitis clinical trials currently recruiting in Indianapolis, IN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 27 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated July 17, 2026 from ClinicalTrials.gov