Indianapolis, INDIANA8 Active Studies

Breast Cancer Clinical Trials in Indianapolis, INDIANA

Find 8 actively recruiting breast cancer clinical trials in Indianapolis, INDIANA. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
4,704
Enrolling

Recruiting Breast Cancer Studies in Indianapolis

RecruitingIndianapolis, INDIANANCT06966700

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Researchers are looking for new ways to treat types of breast cancer that are both: * High-risk, which means the cancer may have a higher chance of getting worse or coming back after treatment * Earl...

2,400 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingIndianapolis, INDIANANCT05827081

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

The purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and standard adjuvant endocrine therapy (ET) on in...

1,400 participants
Novartis Pharmaceuticals
View Study Details
RecruitingIndianapolis, INDIANANCT04569747

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer

This research study is studying a combination of HER2-directed therapies (trastuzumab and pertuzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. Th...

375 participants
Dana-Farber Cancer Institute
View Study Details
RecruitingIndianapolis, INDIANANCT05846789

SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers

This is a randomized Phase II study of standard of care (SOC) chemotherapy monotherapy vs. SOC chemotherapy combined with tocilizumab in in Black and non-Black patients with metastatic triple negative...

168 participants
Kathy Miller
View Study Details
RecruitingIndianapolis, INDIANANCT06590857

Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.

Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs....

124 participants
RayzeBio, Inc.
View Study Details
RecruitingIndianapolis, INDIANANCT05557877

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the ris...

100 participants
Mayo Clinic
View Study Details
RecruitingIndianapolis, INDIANANCT04841148

Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast cancer patients who are found to harbor dissemin...

96 participants
Abramson Cancer Center at Penn Medicine
View Study Details
RecruitingIndianapolis, INDIANANCT04711824

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

This study is a Phase I/II study evaluating the safety and effectiveness of focused radiation therapy (radiosurgery) together with olaparib, followed by immunotherapy, for patients with brain metastas...

41 participants
Colette Shen
View Study Details

About Breast Cancer Clinical Trials in Indianapolis

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Indianapolis, INDIANA. These studies are seeking a combined 4,704 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Novartis Pharmaceuticals, Dana-Farber Cancer Institute and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Indianapolis — FAQ

Are there breast cancer clinical trials in Indianapolis?

Yes, there are 8 breast cancer clinical trials currently recruiting in Indianapolis, INDIANA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov