Indianapolis, INDIANA11 Active Studies

Inflammatory Bowel Disease Clinical Trials in Indianapolis, INDIANA

Find 11 actively recruiting inflammatory bowel disease clinical trials in Indianapolis, INDIANA. Connect with local research sites and explore new treatment options.

11
Active Trials
7
Sponsors
2,276
Enrolling

Recruiting Inflammatory Bowel Disease Studies in Indianapolis

RecruitingIndianapolis, INDIANANCT05781152

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pai...

900 participants
Connecticut Children's Medical Center
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RecruitingIndianapolis, INDIANANCT06227910

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

396 participants
Takeda
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RecruitingIndianapolis, INDIANANCT05660746

Precise Infliximab Exposure and Pharmacodynamic Control

Approximately 3 million people in the United States are living with inflammatory bowel disease, which includes Crohn's Disease (CD). There are limited treatment options approved for use in children an...

180 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingIndianapolis, INDIANANCT05923073

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants with Crohn's Disease (CD) at the end of maintenance therapy (Week 52) among partic...

120 participants
Janssen Research & Development, LLC
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RecruitingIndianapolis, INDIANANCT04779320

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with vedoliz...

120 participants
Takeda
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RecruitingIndianapolis, INDIANANCT06260163

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy of guselkumab in pediatric participants with moderately to severely active ulcerative colitis at the end of maintenance therapy among participants...

120 participants
Janssen Research & Development, LLC
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RecruitingIndianapolis, INDIANANCT06332534

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms includ...

110 participants
AbbVie
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RecruitingIndianapolis, INDIANANCT05995353

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This study will assess the pharmacokinetics, ...

110 participants
AbbVie
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RecruitingIndianapolis, INDIANANCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

90 participants
Eli Lilly and Company
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RecruitingIndianapolis, INDIANANCT04314375

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

This is a randomized, double-blind, placebo-controlled, multicenter, study to evaluate the efficacy, safety, and pharmacokinetics (PK) of budesonide extended-release tablets for the induction of remis...

70 participants
Bausch Health Americas, Inc.
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RecruitingIndianapolis, INDIANANCT05784246

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC)....

60 participants
Eli Lilly and Company
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About Inflammatory Bowel Disease Clinical Trials in Indianapolis

Inflammatory bowel disease (IBD) encompasses chronic inflammatory conditions of the gastrointestinal tract, primarily Crohn's disease and ulcerative colitis. It affects millions worldwide and can cause debilitating symptoms. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 11 inflammatory bowel disease clinical trials recruiting participants in Indianapolis, INDIANA. These studies are seeking a combined 2,276 participants. Research is being sponsored by Connecticut Children's Medical Center, Takeda, Children's Hospital Medical Center, Cincinnati and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Inflammatory Bowel Disease Clinical Trials in Indianapolis — FAQ

Are there inflammatory bowel disease clinical trials in Indianapolis?

Yes, there are 11 inflammatory bowel disease clinical trials currently recruiting in Indianapolis, INDIANA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What inflammatory bowel disease treatments are being tested?

The 11 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for inflammatory bowel disease.

Data updated March 2, 2026 from ClinicalTrials.gov