10 Breast Cancer Clinical Trials in Iowa City, IA (2026)

Q: How do I join a clinical trial in Iowa City?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you.

Recruiting Breast Cancer Studies in Iowa City

NCT06324357Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People can take part in this study if their tumours show HER...

Iowa City, IAPHASE1768 participantsBoehringer Ingelheim

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NCT07029399Recruiting

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

The goal of this open-label dose escalation and expansion study is to evaluate the safety and tolerability of NKT5097 in adults with advanced/metastatic tumors (emphasis on breast cancer and solid tum...

Iowa City, IAPHASE1361 participantsNiKang Therapeutics, Inc.

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NCT05467891Recruiting

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

This is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional recurrence of HR-positive, HER2-negative breast can...

Iowa City, IAPHASE2200 participantsOana Danciu

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NCT05508906Recruiting

Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

This is a Phase 1b open-label, 2-part study in 3 treatment groups. The 3 treatment groups are as follows: Treatment Group 1: Palazestrant (OP-1250) in combination with ribociclib (KISQALI®, Novartis ...

Iowa City, IAPHASE1190 participantsOlema Pharmaceuticals, Inc.

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NCT05704062Recruiting

Quantitative MRI Assessment of Breast Cancer Therapy Response

The goal of this observational study is to investigate and validate multi-parametric magnetic resonance imaging (MRI) modalities for assessment of breast cancer response to neoadjuvant chemotherapy in...

Iowa City, IA135 participantsCorewell Health East

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NCT06756932Recruiting

BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

This is a dose escalation and dose expansion study to assess the safety and tolerability of BGB-21447 (a B-cell leukemia/lymphoma 2 inhibitor, Bcl-2i) in combination with fulvestrant, with or without ...

Iowa City, IAPHASE1120 participantsBeOne Medicines

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NCT03096418Recruiting

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

The hypothesis of this study is that paclitaxel levels increase chromosomal instability (CIN) in tumors and this is lethal to tumors that have pre-existing CIN. Treatment will be administered on an ou...

Iowa City, IAPHASE450 participantsUniversity of Wisconsin, Madison

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NCT06169371Recruiting

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

This is a post-marketing single arm, phase IV trial in which patients with high-risk early-stage HR+HER2- breast cancer will receive adjuvant abemaciclib in combination with endocrine therapy (ET) Aft...

Iowa City, IAPHASE450 participantsUniversity of Illinois at Chicago

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NCT06586047Recruiting

Breast Cancer PSMA PET

The purpose of this research is to determine the expression of Prostate Specific Membrane Antigen(PSMA) in metastatic Triple Negative Breast Cancer (TNBC) patients using Fludeoxyglucose F18 (FDG) PET/...

Iowa City, IAEARLY_PHASE130 participantsAhmad Shariftabrizi

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NCT07765927Recruiting

Exercise Oncology Clinic Pilot Feasibility Trial

The purpose of this pilot study is to test a supervised exercise program for adults with a history of breast or gynecologic cancer to see if it is safe, helpful, and easy to take part in....

Iowa City, IANA30 participantsJess S. Gorzelitz

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About Breast Cancer Clinical Trials in Iowa City

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 10 breast cancer clinical trials recruiting participants in Iowa City, IA. These studies are seeking a combined 1,934 participants. Research is being sponsored by Boehringer Ingelheim, NiKang Therapeutics, Inc., Oana Danciu and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Iowa City — FAQ

Are there breast cancer clinical trials in Iowa City?

Yes, there are 10 breast cancer clinical trials currently recruiting in Iowa City, IA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Iowa City?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you about next steps.

Are clinical trials in Iowa City free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Iowa City studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 10 active trials in Iowa City are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated August 31, 2026 from ClinicalTrials.gov