12 Geographic Atrophy Clinical Trials in Iowa City, IA (2026)

Q: How do I join a clinical trial in Iowa City?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you.

Recruiting Geographic Atrophy Studies in Iowa City

NCT05046600Recruiting

Registry of Arthrex Hand and Wrist Products

A Multi-Center, Prospective Registry to Evaluate the Continued Safety and Effectiveness of Hand and Wrist Products...

Iowa City, IA650 participantsArthrex, Inc.

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NCT05482893Recruiting

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

This is a first-in-human, Phase 1/2, open-label, dose escalation and dose expansion and combination study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and prelimi...

Iowa City, IAPHASE1350 participantsPhanes Therapeutics

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NCT06679855Recruiting

Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

The goal of this Phase 3, randomized, masked clinical trial is to is to find out whether milrinone, when given to infants after PDA closure, will help the heart work better by supplying oxygen to the ...

Iowa City, IAPHASE3316 participantsNICHD Neonatal Research Network

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NCT04660760Recruiting

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

This phase II trial studies the effect of the combination of ramucirumab and trifluridine/tipiracil or paclitaxel in treating patients with previously treated gastric or gastroesophageal junction canc...

Iowa City, IAPHASE2116 participantsAcademic and Community Cancer Research United

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NCT06159608Recruiting

Sex Differences in the Vascular Effects of E-cigarette Use

The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in ...

Iowa City, IAEARLY_PHASE180 participantsAnna Stanhewicz, PhD

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NCT07406633Recruiting

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

This study will test an experimental drug called KQB198 in combination with imatinib. The goal is to determine if this combination is safe and tolerable and assess how effective the combination is at ...

Iowa City, IAPHASE246 participantsKumquat Biosciences Inc.

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NCT07223944Recruiting

A Gaucher Disease Gene Therapy Trial With FLT201

This study is a Phase 3, non-randomized, multicenter, efficacy and safety study in adult patients with Gaucher disease Type 1, on stable treatment with enzyme replacement therapy (ERT) or substrate re...

Iowa City, IAPHASE345 participantsSpur Therapeutics

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NCT06989359Recruiting

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

This Phase 2 study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney diseases....

Iowa City, IAPHASE245 participantsADARx Pharmaceuticals, Inc.

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NCT04422912Recruiting

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

A phase 1/2, open-label, safety and dosing study of autologous CART cells (desmoglein 3 chimeric autoantibody receptor T cells \[DSG3-CAART\] or CD19-specific Chimeric Antigen Receptor T cells \[CABA-...

Iowa City, IAPHASE140 participantsCabaletta Bio

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NCT07146906Recruiting

A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

The purpose of the study is to assess the effect of zigakibart on IgA nephropathy (IgAN) disease progression....

Iowa City, IAPHASE232 participantsNovartis Pharmaceuticals

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NCT06586047Recruiting

Breast Cancer PSMA PET

The purpose of this research is to determine the expression of Prostate Specific Membrane Antigen(PSMA) in metastatic Triple Negative Breast Cancer (TNBC) patients using Fludeoxyglucose F18 (FDG) PET/...

Iowa City, IAEARLY_PHASE130 participantsAhmad Shariftabrizi

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NCT06489249Recruiting

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

Iowa City, IAEARLY_PHASE124 participantsUniversity of Iowa

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About Geographic Atrophy Clinical Trials in Iowa City

Geographic atrophy is the advanced form of dry age-related macular degeneration, involving progressive loss of retinal cells. It leads to enlarging blind spots in central vision. Recently approved complement inhibitor therapies can slow progression.

There are currently 12 geographic atrophy clinical trials recruiting participants in Iowa City, IA. These studies are seeking a combined 1,774 participants. Research is being sponsored by Arthrex, Inc., Phanes Therapeutics, NICHD Neonatal Research Network and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Geographic Atrophy Clinical Trials in Iowa City — FAQ

Are there geographic atrophy clinical trials in Iowa City?

Yes, there are 12 geographic atrophy clinical trials currently recruiting in Iowa City, IA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Iowa City?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you about next steps.

Are clinical trials in Iowa City free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Iowa City studies also compensate for your time and travel.

What geographic atrophy treatments are being tested?

The 12 active trials in Iowa City are testing new therapies including novel drugs, biologics, and treatment approaches for geographic atrophy.

Data updated October 16, 2026 from ClinicalTrials.gov