26 Pulmonary Hypertension Clinical Trials in Iowa City, IA (2026)

Q: Are there pulmonary hypertension clinical trials in Iowa City?

Yes, there are 26 pulmonary hypertension clinical trials currently recruiting in Iowa City, IA.

Q: How do I join a clinical trial in Iowa City?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you.

Q: Are clinical trials in Iowa City free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Pulmonary Hypertension Studies in Iowa City

NCT07609394Recruiting

Duchenne Electronic Health Record Study

This study aims to collect retrospective and prospective, long-term data of patients with dystrophinopathy (including Duchenne, Becker, and female carriers) through electronic transfer. At select clin...

Iowa City, IA2,500 participantsThe Duchenne Registry

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NCT05685238Recruiting

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

This study is looking at how Mim8 works in people with haemophilia A, who either have inhibitors or do not have inhibitors. Mim8 is a new medicine that will be used to avoid bleeding episodes. Mim8 wo...

Iowa City, IAPHASE3451 participantsNovo Nordisk A/S

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NCT04924075Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

This is a study to evaluate the efficacy and safety of belzutifan monotherapy in participants with advanced pheochromocytoma/paraganglioma (PPGL), pancreatic neuroendocrine tumor (pNET), von Hippel-Li...

Iowa City, IAPHASE2355 participantsMerck Sharp & Dohme LLC

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NCT05826535Recruiting

Study of LYL314 in Aggressive Large B-Cell Lymphoma

This is a Phase 1/2, multi-center, open-label study evaluating the safety and efficacy of LYL314, a dual-targeting chimeric antigen receptor (CAR) targeting cluster of differentiation (CD)19 and CD20 ...

Iowa City, IAPHASE1270 participantsLyell Immunopharma, Inc.

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NCT06526793Recruiting

AZD0486 as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

This is a Phase 2 global, multi-center, open-label study to assess the efficacy, safety and tolerability of AZD0486 monotherapy in adult participants with relapsed/refractory B-cell non-Hodgkin lympho...

Iowa City, IAPHASE2270 participantsAstraZeneca

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NCT05145127Recruiting

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

Study B7841007 is an open-label extension study to assess the long-term safety, tolerability, and efficacy of prophylaxis treatment with marstacimab in participants who did not require "Early Terminat...

Iowa City, IAPHASE3245 participantsPfizer

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NCT07101328Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

The purpose of this study is to find the best dose of the drug and measure the safety and efficacy of LY4152199 in participants with previously treated B-cell malignancies. Participants will have the ...

Iowa City, IAPHASE1215 participantsEli Lilly and Company

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NCT07038200Recruiting

A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous AOC 1020 for the Treatment of Facioscapulohumeral Muscular Dystrophy (FSHD)...

Iowa City, IAPHASE3200 participantsAvidity Biosciences, Inc.

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NCT00313677Recruiting

Clinical Trial Readiness for the Dystroglycanopathies

The purpose of the study is to describe the early signs and symptoms of the dystroglycanopathies, and to gather information that will be required for future clinical trials....

Iowa City, IA190 participantsKatherine Mathews

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NCT06581198Recruiting

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

Iowa City, IAPHASE2179 participantsNovartis Pharmaceuticals

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NCT05481879Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

The primary purpose of the study is to evaluate the safety and tolerability of multiple intravenous (IV) doses of DYNE-101 administered to participants with Myotonic Dystrophy Type 1 (DM1). The study...

Iowa City, IAPHASE1116 participantsDyne Therapeutics

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NCT07109219Recruiting

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

The study is intended to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Cell acute lymphoblastic leukemia (r/r B-AL...

Iowa City, IAPHASE183 participantsAstraZeneca

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NCT05004129Recruiting

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

This is an open-label phase 2/3 study for individuals with Congenital Myotonic Dystrophy (Congenital DM1) who participated in the preceding AMO-02-MD-2-003 study or individuals with either Congenital ...

Iowa City, IAPHASE276 participantsAMO Pharma Limited

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NCT07085104Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) ...

Iowa City, IAPHASE166 participantsAllogene Therapeutics

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NCT05693142Recruiting

AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

RGX-202 is a gene therapy designed to deliver a transgene for a novel microdystrophin that includes functional elements of naturally-occurring dystrophin including the C-Terminal (CT) domain. This is...

Iowa City, IAPHASE265 participantsREGENXBIO Inc.

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NCT05987449Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

WP44714 is a Phase I/II, open-label, non-randomized, global, multicenter trial consisting of two parts: * Part 1 is a multiple-ascending dose (MAD) study in adult and adolescent male participants wit...

Iowa City, IAPHASE160 participantsHoffmann-La Roche

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NCT06300307Recruiting

Study of ATX-01 in Participants With DM1

The goal of this clinical trial is to test ATX-01 in participants with myotonic dystrophy type 1 (DM1). The main question it aims to answer is if ATX-01 is safe and well tolerated. The trial will comp...

Iowa City, IAPHASE156 participantsARTHEx Biotech S.L.

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NCT06412666Recruiting

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

The purpose of this study is to evaluate the efficacy, safety and PK of aficamten in a pediatric population with symptomatic obstructive hypertrophic cardiomyopathy (oHCM)....

Iowa City, IAPHASE255 participantsCytokinetics

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NCT03681561Recruiting

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

This is a Phase I/II, multicenter, open-label, dose escalation/dose-expansion study to evaluate the tolerability, safety, and the maximum tolerated dose (MTD) of ruxolitinib when given with fixed dose...

Iowa City, IAPHASE154 participantsVeronika Bachanova

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NCT07047144Recruiting

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

This double-blind, Phase 2, multiple-dose study will be conducted to evaluate the PK/PD, efficacy, safety, and tolerability of apitegromab in subjects \<2 years old with 5q autosomal recessive SMA who...

Iowa City, IAPHASE252 participantsScholar Rock, Inc.

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NCT06165341Recruiting

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

The liver produces a protein called alpha-1 antitrypsin (AAT). AAT is normally released into the bloodstream. In some people, the liver makes an abnormal version of the AAT protein, called Z-AAT. Maki...

Iowa City, IAPHASE350 participantsTakeda

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NCT06534060Recruiting

MB-105 in Patients With CD5 Positive T-cell Lymphoma

This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon tw...

Iowa City, IAPHASE246 participantsMarch Biosciences Inc

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NCT06503367Recruiting

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

The goal of this observational study is to understand how young children with LAMA2-related dystrophy move and change over time. We will also learn about how this condition impacts other body systems....

Iowa City, IA44 participantsNationwide Children's Hospital

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NCT07571746Recruiting

A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease

The purpose of this study is to assess the safety, tolerability, pharmacokinetic, and efficacy of surovatamig administered by subcutaneous injection in adult participants with primary membranous nephr...

Iowa City, IAPHASE243 participantsAstraZeneca

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NCT07220564Recruiting

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

This study will test how different doses of study medicine (Inno8) work in the bodies of people with haemophilia A. The purpose of the study is to see if Inno8 is safe to use for people with haemophil...

Iowa City, IAPHASE130 participantsNovo Nordisk A/S

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NCT06441136Recruiting

Characterizing the Impact of Presbyphonia on Social Interaction

The purpose of this study is to determine if presbyphonia, or voice disorder caused by age-related change in the larynx, is associated with change in social interaction. This proposal investigates the...

Iowa City, IANA25 participantsMatthew R. Hoffman

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About Pulmonary Hypertension Clinical Trials in Iowa City

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 26 pulmonary hypertension clinical trials recruiting participants in Iowa City, IA. These studies are seeking a combined 5,796 participants. Research is being sponsored by The Duchenne Registry, Novo Nordisk A/S, Merck Sharp & Dohme LLC and 20 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Iowa City — FAQ

Are there pulmonary hypertension clinical trials in Iowa City?

Yes, there are 26 pulmonary hypertension clinical trials currently recruiting in Iowa City, IA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Iowa City?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you about next steps.

Are clinical trials in Iowa City free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Iowa City studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 26 active trials in Iowa City are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated July 17, 2026 from ClinicalTrials.gov