Irvine, CA5 Active Studies

Bladder Cancer Clinical Trials in Irvine, CA

Find 5 actively recruiting bladder cancer clinical trials in Irvine, CA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
1,652
Enrolling

Recruiting Bladder Cancer Studies in Irvine

RecruitingIrvine, CANCT02138734

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

This is a Phase Ib/IIb, randomized, two-cohort, open-label, multicenter study of intravesical N-803 plus BCG versus BCG alone, in BCG naïve patients with high-grade NMIBC....

596 participants
ImmunityBio, Inc.
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RecruitingIrvine, CANCT04879329

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

This study is being done to see if a drug called disitamab vedotin, alone or with pembrolizumab, works to treat HER2 expressing urothelial cancer. It will also test how safe the drug is for participan...

372 participants
Seagen, a wholly owned subsidiary of Pfizer
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RecruitingIrvine, CANCT04752722

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

This study will evaluate the safety and efficacy of intravesical administration of EG-70 in the bladder and its effect on bladder tumors in patients with NMIBC. This study study consists of two phase...

350 participants
enGene, Inc.
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RecruitingIrvine, CANCT04579224

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

This phase III trial compares the usual chemotherapy treatment to eribulin plus gemcitabine in treating patients with urothelial cancer that has spread from where it first started (primary site) to ot...

184 participants
National Cancer Institute (NCI)
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RecruitingIrvine, CANCT03375307

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

This phase II trial studies how well olaparib works in treating patients with bladder cancer and other genitourinary tumors with deoxyribonucleic acid (DNA)-repair defects that has spread to other pla...

150 participants
National Cancer Institute (NCI)
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About Bladder Cancer Clinical Trials in Irvine

Bladder cancer occurs in the tissues of the bladder and is one of the most common cancers. It has a high recurrence rate, requiring ongoing monitoring. Treatments include surgery, intravesical therapy, chemotherapy, and immunotherapy.

There are currently 5 bladder cancer clinical trials recruiting participants in Irvine, CA. These studies are seeking a combined 1,652 participants. Research is being sponsored by ImmunityBio, Inc., Seagen, a wholly owned subsidiary of Pfizer, enGene, Inc. and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Bladder Cancer Clinical Trials in Irvine — FAQ

Are there bladder cancer clinical trials in Irvine?

Yes, there are 5 bladder cancer clinical trials currently recruiting in Irvine, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Irvine?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Irvine research site will contact you about next steps.

Are clinical trials in Irvine free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Irvine studies also compensate for your time and travel.

What bladder cancer treatments are being tested?

The 5 active trials in Irvine are testing new therapies including novel drugs, biologics, and treatment approaches for bladder cancer.

Data updated March 2, 2026 from ClinicalTrials.gov