Irvine, CA13 Active Studies

Erectile Dysfunction Clinical Trials in Irvine, CA

Find 13 actively recruiting erectile dysfunction clinical trials in Irvine, CA. Connect with local research sites and explore new treatment options.

13
Active Trials
11
Sponsors
2,688
Enrolling

Recruiting Erectile Dysfunction Studies in Irvine

RecruitingIrvine, CANCT06697197

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

The purpose of this study is to test the safety and efficacy of BMS-986482 alone and as combination therapy in participants with advanced solid tumors....

413 participants
Bristol-Myers Squibb
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RecruitingIrvine, CANCT04143711

Study of DF1001 in Patients with Advanced Solid Tumors

DF1001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase ...

378 participants
Dragonfly Therapeutics
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RecruitingIrvine, CANCT05123482

A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies

This research study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer agents...

370 participants
AstraZeneca
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RecruitingIrvine, CANCT05315700

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

The purpose of this study is to establish the recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of ORIC-...

350 participants
ORIC Pharmaceuticals
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RecruitingIrvine, CANCT05597839

Study of DF9001 in Patients With Advanced Solid Tumors

DF9001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase ...

242 participants
Dragonfly Therapeutics
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RecruitingIrvine, CANCT04585750

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tum...

230 participants
PMV Pharmaceuticals, Inc
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RecruitingIrvine, CANCT05023486

NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies

Multicenter, open-label study in patients with advanced or metastatic solid tumor malignancies to evaluate the safety, tolerability, and preliminary anti-tumor efficacy, PK, and pharmacodynamics of co...

140 participants
Novita Pharmaceuticals, Inc.
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RecruitingIrvine, CANCT04896697

Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors

This is a first-in-human, Phase 1/2, multicenter, open-label study designed to evaluate the safety and tolerability of vilastobart (XTX101) as monotherapy and vilastobart (XTX101) and atezolizumab com...

136 participants
Xilio Development, Inc.
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RecruitingIrvine, CANCT04068194

Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies

This phase I/II trial studies the best dose and side effects of peposertib and to see how well it works with avelumab and hypofractionated radiation therapy in treating patients with solid tumors and ...

103 participants
National Cancer Institute (NCI)
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RecruitingIrvine, CANCT06399757

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus o...

100 participants
Apollo Therapeutics Ltd
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RecruitingIrvine, CANCT05327010

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

This phase II trial tests whether ZEN003694 (ZEN-3694) in combination with talazoparib works to shrink tumors in patients with solid tumors that are unlikely to be cured or controlled with treatment a...

88 participants
National Cancer Institute (NCI)
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RecruitingIrvine, CANCT06253130

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

This study will evaluate the preliminary efficacy of IMP1734 in patients with recurrent advanced/metastatic breast cancer, ovarian cancer and metastatic castrate resistant prostate cancer (mCRPC) with...

70 participants
Eikon Therapeutics
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RecruitingIrvine, CANCT05551793

Regeneron AA Multicenter (Dupilumab)

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affe...

68 participants
Emma Guttman
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About Erectile Dysfunction Clinical Trials in Irvine

Erectile dysfunction is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It affects about 30 million men in the U.S. and is often a sign of underlying cardiovascular disease. Treatment includes PDE5 inhibitors, vacuum devices, and penile implants.

There are currently 13 erectile dysfunction clinical trials recruiting participants in Irvine, CA. These studies are seeking a combined 2,688 participants. Research is being sponsored by Bristol-Myers Squibb, Dragonfly Therapeutics, AstraZeneca and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Erectile Dysfunction Clinical Trials in Irvine — FAQ

Are there erectile dysfunction clinical trials in Irvine?

Yes, there are 13 erectile dysfunction clinical trials currently recruiting in Irvine, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Irvine?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Irvine research site will contact you about next steps.

Are clinical trials in Irvine free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Irvine studies also compensate for your time and travel.

What erectile dysfunction treatments are being tested?

The 13 active trials in Irvine are testing new therapies including novel drugs, biologics, and treatment approaches for erectile dysfunction.

Data updated March 2, 2026 from ClinicalTrials.gov