Irvine, CALIFORNIA6 Active Studies

Prostate Cancer Clinical Trials in Irvine, CALIFORNIA

Find 6 actively recruiting prostate cancer clinical trials in Irvine, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
3,073
Enrolling

Recruiting Prostate Cancer Studies in Irvine

RecruitingIrvine, CALIFORNIANCT06925737

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-...

1,440 participants
Merck Sharp & Dohme LLC
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RecruitingIrvine, CALIFORNIANCT06691984

Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)

The main objective of the study is to compare overall survival in participants receiving xaluritamig versus investigator's choice (cabazitaxel or second androgen receptor-directed therapy \[ARDT\])....

675 participants
Amgen
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RecruitingIrvine, CALIFORNIANCT06632977

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

This phase II trial evaluates whether genetic testing in prostate cancer is helpful in deciding which study treatment patients are assigned. Patient cancer tissue samples are obtained from a previous ...

474 participants
Alliance for Clinical Trials in Oncology
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RecruitingIrvine, CALIFORNIANCT05053152

Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study

This phase II trial compares the usual treatment of radiation therapy alone to using the study drug, relugolix, plus the usual radiation therapy in patients with castration-sensitive prostate cancer t...

194 participants
NRG Oncology
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RecruitingIrvine, CALIFORNIANCT03456843

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

This randomized phase II trial studies how well surgical removal of the prostate and antiandrogen therapy with or without docetaxel work in treating men with newly diagnosed prostate cancer that has s...

190 participants
Yale University
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RecruitingIrvine, CALIFORNIANCT06402331

FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)

This is an open-label, randomized, multicenter study of FPI-2265 (225Ac-PSMA-I\&T). Patient population is adult participants with PSMA positive mCRPC who have had previous treatment with with 177Lu-PS...

100 participants
Fusion Pharmaceuticals Inc.
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About Prostate Cancer Clinical Trials in Irvine

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 6 prostate cancer clinical trials recruiting participants in Irvine, CALIFORNIA. These studies are seeking a combined 3,073 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Amgen, Alliance for Clinical Trials in Oncology and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Irvine — FAQ

Are there prostate cancer clinical trials in Irvine?

Yes, there are 6 prostate cancer clinical trials currently recruiting in Irvine, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Irvine?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Irvine research site will contact you about next steps.

Are clinical trials in Irvine free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Irvine studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 6 active trials in Irvine are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated March 2, 2026 from ClinicalTrials.gov