35 Myalgic Encephalomyelitis Clinical Trials in Jacksonville, FL (2026)

Q: How do I join a clinical trial in Jacksonville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you.

Recruiting Myalgic Encephalomyelitis Studies in Jacksonville

NCT06583408Recruiting

The REgistry of Very Early Estrogen and AnovuLation

The purpose of this study is to to build a registry of women with early estrogen loss due to Functional Hypothalamic Amenorrhea (FHA) to understand the prevalence, racial and ethnic diversity of this ...

Jacksonville, FL100,000 participantsMayo Clinic

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NCT05685745Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveri...

Jacksonville, FL5,000 participantsThe University of Texas Health Science Center, Houston

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NCT05354141Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

To evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EVs), ExoFlo, versus placebo for the treatment of hospitaliz...

Jacksonville, FLPHASE3970 participantsDirect Biologics, LLC

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NCT06876649Recruiting

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib....

Jacksonville, FLPHASE4787 participantsEli Lilly and Company

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NCT06641466Recruiting

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience ...

Jacksonville, FLPHASE3723 participantsPfizer

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NCT00869817Recruiting

Dominantly Inherited Alzheimer Network (DIAN)

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation....

Jacksonville, FL700 participantsWashington University School of Medicine

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NCT06112314Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

This is a phase 3, randomized, controlled study of brenetafusp (IMC-F106C) plus nivolumab compared to standard nivolumab regimens in HLA-A\*02:01-positive participants with previously untreated advanc...

Jacksonville, FLPHASE3680 participantsImmunocore Ltd

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NCT06976203Recruiting

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease...

Jacksonville, FLPHASE3586 participantsBristol-Myers Squibb

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NCT05549297Recruiting

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including cli...

Jacksonville, FLPHASE3540 participantsImmunocore Ltd

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NCT07015190Recruiting

Neoadjuvant Darovasertib in Primary Uveal Melanoma

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)...

Jacksonville, FLPHASE3520 participantsIDEAYA Biosciences

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NCT06743126Recruiting

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

This clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and tolerability of treatment wit...

Jacksonville, FLPHASE3360 participantsImmatics US, Inc.

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NCT05245500Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid tumor malignancy wit...

Jacksonville, FLPHASE1336 participantsBristol-Myers Squibb

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NCT07154290Recruiting

A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

This study will evaluate two study drugs called ubamatamab and REGN7075, to see if they can help treat advanced or metastatic Non-Small Cell Lung Cancer (NSCLC), and sarilumab, to evaluate to see if i...

Jacksonville, FLPHASE2300 participantsRegeneron Pharmaceuticals

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NCT05655312Recruiting

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

In this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor (MC1R) is being evaluate...

Jacksonville, FLPHASE1300 participantsPerspective Therapeutics

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NCT04149496Recruiting

IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle ...

Jacksonville, FLNA300 participantsBruce Rose, MD

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NCT06581406Recruiting

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

The purpose of this study is to measure the clinical benefits of the combination of RP2 and nivolumab as compared with the combination of nivolumab and ipilimumab in patients with metastatic uveal mel...

Jacksonville, FLPHASE2280 participantsReplimune Inc.

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NCT05219617Recruiting

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in ped...

Jacksonville, FLPHASE3252 participantsSK Life Science, Inc.

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NCT05960929Recruiting

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give I...

Jacksonville, FLPHASE3220 participantsONY

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NCT05641688Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

This study is an open-label, multi-center, non-randomized pivotal Phase 3 study to assess the efficacy and safety of PET imaging with \[18F\]PI-2620 for detection of tau deposition in subjects with Al...

Jacksonville, FLPHASE3200 participantsLife Molecular Imaging Ltd

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NCT07206056Recruiting

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

This is a two-part, Phase I/II, open-label, global, multicenter study assessing the safety and efficacy of the combination of tulmimetostat (DZR123) and JSB462 (luxdegalutamide) versus standard of car...

Jacksonville, FLPHASE1188 participantsNovartis Pharmaceuticals

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NCT06872125Recruiting

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

The purpose of the study is to evaluate the efficacy, safety, and tolerability of zorevunersen in Patients with Dravet syndrome....

Jacksonville, FLPHASE3170 participantsStoke Therapeutics, Inc

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NCT04594187Recruiting

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

This phase II trial seeks to determine the role of nodal radiation therapy after sentinel lymph node biopsy (SLNB) for patients with high risk sentinel lymph node positive melanoma who are planned for...

Jacksonville, FLPHASE2168 participantsM.D. Anderson Cancer Center

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NCT03750227Recruiting

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

This phase III trial studies the side effects and how well stereotactic radiosurgery (SRS) works before or after surgery in patients with tumors that has spread to the brain or that can be removed by ...

Jacksonville, FLPHASE3140 participantsMayo Clinic

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NCT05880810Recruiting

Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients

The purpose of this study is to measure differences in diabetes control with the use of continuous glucose monitor (CGM) and diabetes education compared with standard of care for glucose monitoring (g...

Jacksonville, FLNA100 participantsMayo Clinic

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NCT05222620Recruiting

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

This phase II trial compares the effect of single fraction stereotactic radiosurgery to fractionated stereotactic radiosurgery for the treatment of patients with cancer that has spread to the brain (m...

Jacksonville, FLPHASE290 participantsMayo Clinic

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NCT07332091Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-rel...

Jacksonville, FLPHASE284 participantsCSL Behring

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NCT05796388Recruiting

A Study of Virtual Reality and Linaclotide for IBS-C

The purpose of this study is to determine if adult patients with IBS-C will report an overall greater improvement in IBS symptoms and quality of life when treated with a combination of linaclotide (st...

Jacksonville, FLNA65 participantsMayo Clinic

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NCT03949855Recruiting

Belimumab With Rituximab for Primary Membranous Nephropathy

The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete or partial remission (CR or PR) compared to rituxim...

Jacksonville, FLPHASE258 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT05938465Recruiting

Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)

The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement frequency in patients with an ileal pouch-anal ...

Jacksonville, FLPHASE150 participantsExegi Pharma, LLC

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NCT06401356Recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

The purpose of this study is to evaluate the long-term safety and the clinical benefit of pelabresib in patients with hematological and/or solid tumor indications or advanced malignancies. Additionall...

Jacksonville, FLPHASE350 participantsNovartis Pharmaceuticals

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NCT04991948Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

The purpose of the CYAD-101-002 study is to assess the safety and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered concurrently with FOLFOX chemoth...

Jacksonville, FLPHASE134 participantsCelyad Oncology SA

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NCT07020819Recruiting

An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

The goal of this open label study is to measure pharmacokinetics, pharmacodynamics, early efficacy, and safety of tanruprubart in adult and pediatric participants, in the United States, Canada, and Eu...

Jacksonville, FLPHASE330 participantsAnnexon, Inc.

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NCT06701812Recruiting

Digoxin Medulloblastoma Study

The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients....

Jacksonville, FLPHASE223 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT06684470Recruiting

Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator

The purpose of this research is to study the added benefit of treating IBS symptoms with a medication called mirtazapine in treating IBS symptoms when paired with a low-FODMAP diet compared to a low-F...

Jacksonville, FLEARLY_PHASE120 participantsMayo Clinic

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NCT07194044Recruiting

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

This single arm study is designed to demonstrate the feasibility of a radically different approach for an exceptionally high-risk subset of MES with widely metastatic disease (WMES). We incorporate th...

Jacksonville, FLPHASE115 participantsH. Lee Moffitt Cancer Center and Research Institute

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About Myalgic Encephalomyelitis Clinical Trials in Jacksonville

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 35 myalgic encephalomyelitis clinical trials recruiting participants in Jacksonville, FL. These studies are seeking a combined 114,339 participants. Research is being sponsored by Mayo Clinic, The University of Texas Health Science Center, Houston, Direct Biologics, LLC and 23 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in Jacksonville — FAQ

Are there myalgic encephalomyelitis clinical trials in Jacksonville?

Yes, there are 35 myalgic encephalomyelitis clinical trials currently recruiting in Jacksonville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 35 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated October 12, 2026 from ClinicalTrials.gov