7 Lung Cancer Clinical Trials in Kansas City, KS (2026)

Q: How do I join a clinical trial in Kansas City?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Kansas City research site will contact you.

Recruiting Lung Cancer Studies in Kansas City

NCT06345729Recruiting

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

This is a study evaluating the efficacy and safety of MK-1084 with pembrolizumab as first-line treatment in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) with ide...

Kansas City, KSPHASE3600 participantsMerck Sharp & Dohme LLC

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NCT06343402Recruiting

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

A first in human study to evaluate the safety and preliminary antitumor activity of BBO-8520, a KRAS G12C (ON and OFF) inhibitor, as a single agent and in combination with pembrolizumab and BBO-10203 ...

Kansas City, KSPHASE1350 participantsTheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

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NCT02468024Recruiting

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

To Determine if SAbR improves survival over SR in High Risk Operable Stage I NSCLC...

Kansas City, KSPHASE3272 participantsUniversity of Texas Southwestern Medical Center

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NCT04992780Recruiting

Comparing Hypo-fractionated Intensity- Modulated Radiation Therapy to Standard- Fractionated IMRT Along With Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer

The hypothesis for this study is that hypofractionated IMRT to 62.5 Gy in 25 fractions (2.5 Gy/fraction) with concurrent carboplatin and paclitaxel, followed by maintenance durvalumab will improve loc...

Kansas City, KSPHASE250 participantsUniversity of Kansas Medical Center

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NCT04680377Recruiting

Using Microbiome to Predict Durvalumab Toxicity in Post- Concurrent Chemoradiation Therapy (CCRT) NSCLC Patients

This phase IV study is hoping to determine if examining the microbiome in non-small cell lung cancer participants who will receive durvalumab can predict treatment toxicity....

Kansas City, KS44 participantsJun Zhang, MD, PhD

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NCT05332925Recruiting

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC

To test whether it is feasible to perform the 3D-EX functional predictive response bioassay in the context of patients with advanced/metastatic NSCLC receiving immune checkpoint inhibitors in the stan...

Kansas City, KS25 participantsJun Zhang, MD, PhD

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NCT04467723Recruiting

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

The purpose of this study is to see if adding pirfenidone to atezolizumab will increase anti tumor activity and reduce treatment resistance in stage 4 and recurrent non- small cell lung cancer partici...

Kansas City, KSPHASE125 participantsUniversity of Kansas Medical Center

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About Lung Cancer Clinical Trials in Kansas City

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 7 lung cancer clinical trials recruiting participants in Kansas City, KS. These studies are seeking a combined 1,366 participants. Research is being sponsored by Merck Sharp & Dohme LLC, TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics), University of Texas Southwestern Medical Center and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Kansas City — FAQ

Are there lung cancer clinical trials in Kansas City?

Yes, there are 7 lung cancer clinical trials currently recruiting in Kansas City, KS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Kansas City?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Kansas City research site will contact you about next steps.

Are clinical trials in Kansas City free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Kansas City studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 7 active trials in Kansas City are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated July 17, 2026 from ClinicalTrials.gov