27 Rheumatoid Arthritis Clinical Trials in La Jolla, CA (2026)

Q: How do I join a clinical trial in La Jolla?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the La Jolla research site will contact you.

Recruiting Rheumatoid Arthritis Studies in La Jolla

NCT05915299Recruiting

US National OCS Heart Perfusion (OHP) Registry

This Registry is a sponsor initiated, multi-center, observational post-approval registry with independent academic oversight....

La Jolla, CA100,000 participantsTransMedics

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NCT05940857Recruiting

US National OCS Liver Perfusion (OLP) Registry

This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted with United Network for Organ Sharing (UNO...

La Jolla, CA100,000 participantsTransMedics

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NCT06578195Recruiting

ASSESS ALL ALS Study

The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic Lateral Sclerosis (ALS) symptomatic, ALS ge...

La Jolla, CA2,000 participantsSt. Joseph's Hospital and Medical Center, Phoenix

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NCT06066502Recruiting

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

The goal of this interventional study is to compare standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with Acute Respiratory Distress Syndrome (ARDS). Particip...

La Jolla, CAPHASE31,100 participantsBeth Israel Deaconess Medical Center

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NCT03242642Recruiting

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device....

La Jolla, CANA1,056 participantsMedtronic Cardiovascular

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NCT05407636Recruiting

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by ...

La Jolla, CAPHASE3714 participantsAbbVie

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NCT07012395Recruiting

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficac...

La Jolla, CAPHASE2645 participantsSpyre Therapeutics, Inc.

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NCT06467357Recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

The purpose of this study is to measure the efficacy and safety of T-DXd with rilvegostomig or T-DXd monotherapy compared with gemcitabine plus cisplatin and durvalumab in patients with advanced treat...

La Jolla, CAPHASE3620 participantsAstraZeneca

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NCT06563895Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different orga...

La Jolla, CAPHASE3587 participantsEidos Therapeutics, a BridgeBio company

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NCT05580562Recruiting

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC...

La Jolla, CAPHASE3510 participantsChimerix

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NCT06075745Recruiting

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

This is a multi-center clinical trial in Cytomegalovirus (CMV) seronegative prospective liver transplant recipients to determine the efficacy of two doses of Cytomegalovirus-Modified Vaccinia Ankara (...

La Jolla, CAPHASE2416 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT07276581Recruiting

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163....

La Jolla, CAPHASE2320 participantsAstraZeneca

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NCT06635148Recruiting

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies....

La Jolla, CAPHASE2274 participantsJanssen Research & Development, LLC

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NCT06500455Recruiting

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from whe...

La Jolla, CAPHASE3269 participantsNRG Oncology

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NCT06585774Recruiting

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

This study will be conducted to compare the efficacy of axatilimab versus placebo in combination with corticosteroids as initial treatment for moderate or severe chronic graft-versus-host disease (cGV...

La Jolla, CAPHASE3240 participantsIncyte Corporation

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NCT06029972Recruiting

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will comp...

La Jolla, CAPHASE2176 participantsGilead Sciences

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NCT04592445Recruiting

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater splanchnic nerve. The study includes peo...

La Jolla, CANA150 participantsAxon Therapies, Inc.

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NCT04748809Recruiting

Effect of Anti-inflammatory Diet in Rheumatoid Arthritis

In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metab...

La Jolla, CANA124 participantsUniversity of California, San Diego

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NCT07142291Recruiting

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

The purpose of this study is to test the effects of PHENOGENE-1A, which is the treatment under investigation in this study. This research will investigate if PHENOGENE-1A can help people with ALS by m...

La Jolla, CAPHASE2105 participantsPhenoNet, Inc.

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NCT07672015Recruiting

Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)

The purpose of the study is to investigate the efficacy of suzetrigine for treatment of acute postoperative pain among surgical patients identified as high risk for persistent postoperative opioid use...

La Jolla, CAPHASE4100 participantsUniversity of California, San Diego

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NCT06902519Recruiting

Study of GS-0151 in Participants With Rheumatoid Arthritis

The goal of this clinical study is to learn more about the study drug GS-0151. The study is done to find how safe, well-tolerated the drug is. This will also assess how the drug is absorbed, modified,...

La Jolla, CAPHASE175 participantsGilead Sciences

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NCT07420400Recruiting

Non-Invasive Detection of Right-to-Left Cardiac Shunts

This study will test the sensitivity of a novel, battery-powered, non-invasive ultrasound device to detect a right-to-left shunt...

La Jolla, CA75 participantsScripps Health

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NCT07489651Recruiting

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces anxiety symptoms in participants with Generalized Anxiety Disorder (GAD) as compared to placebo...

La Jolla, CAPHASE264 participantsReunion Neuroscience Inc

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NCT06895070Recruiting

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

The purpose of this study is to evaluate if Non-Ischemic Heart Preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to pre...

La Jolla, CANA60 participantsXVIVO Perfusion

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NCT06798012Recruiting

A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

CIDP is an autoimmune disease. This means that the body's germ fighting (immune) system attacks itself. In CIDP, the immune system attacks the protective covering around the nerves called myelin. Over...

La Jolla, CAPHASE236 participantsTakeda

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NCT06832306Recruiting

STimulation to Activate RespIration

Multi-center, randomized, controlled, open-label Phase 2 feasibility trial. Subjects on mechanical ventilation (MV) for acute hypoxemic respiratory failure (AHRF) with lung injury (including subjects ...

La Jolla, CANA30 participantsLungpacer Medical Inc.

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NCT06909214Recruiting

A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)

The main purpose of this study is to measure how well adults with new-onset gMG (which means they've had generalized disease signs and/or symptoms for less than 1 year) respond to treatment with efgar...

La Jolla, CAPHASE430 participantsargenx

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About Rheumatoid Arthritis Clinical Trials in La Jolla

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 27 rheumatoid arthritis clinical trials recruiting participants in La Jolla, CA. These studies are seeking a combined 209,776 participants. Research is being sponsored by TransMedics, St. Joseph's Hospital and Medical Center, Phoenix, Beth Israel Deaconess Medical Center and 20 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in La Jolla — FAQ

Are there rheumatoid arthritis clinical trials in La Jolla?

Yes, there are 27 rheumatoid arthritis clinical trials currently recruiting in La Jolla, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in La Jolla?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the La Jolla research site will contact you about next steps.

Are clinical trials in La Jolla free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many La Jolla studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 27 active trials in La Jolla are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated July 18, 2026 from ClinicalTrials.gov