13 Advanced Solid Tumors Clinical Trials in Lake Mary, FL (2026)

Q: How do I join a clinical trial in Lake Mary?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Lake Mary research site will contact you.

Recruiting Advanced Solid Tumors Studies in Lake Mary

NCT05768139Recruiting

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Study STX-478-101 is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 (LY4064809) in participants with...

Lake Mary, FLPHASE1880 participantsEli Lilly and Company

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NCT05382559Recruiting

A Study of ASP3082 in Adults With Advanced Solid Tumors

This is an open-label study. This means that people in this study and clinic staff will know that people will receive ASP3082. The study aims to check how safe and well-tolerated ASP3082 is for people...

Lake Mary, FLPHASE1681 participantsAstellas Pharma Inc

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NCT06431594Recruiting

A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

The goal of this study is to assess the safety and tolerability of Mocertatug Rezetecan . The study will also see how the levels of Mo-Rez change over time at different dose amount...

Lake Mary, FLPHASE1675 participantsGlaxoSmithKline

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NCT06619587Recruiting

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

This is a first-in-human Phase I/II, open-label, multicenter, dose-escalation and expansion study designed to evaluate the safety, pharmacokinetics, and preliminary activity of GDC-7035 as a single ag...

Lake Mary, FLPHASE1410 participantsGenentech, Inc.

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NCT06120283Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

This is a dose escalation and dose expansion study to compare how well BGB-43395, a selective cyclin-dependent kinase 4 (CDK4) inhibitor, works as monotherapy or in combination with fulvestrant, letro...

Lake Mary, FLPHASE1399 participantsBeOne Medicines

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NCT06561685Recruiting

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

The main purpose of this study is to find out whether the study drug, LY4050784, is safe, tolerable and effective in participants alone or in combination with other anticancer agents. In addition, wit...

Lake Mary, FLPHASE1340 participantsEli Lilly and Company

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NCT06459973Recruiting

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

This study is a multicenter, open-label, phase I/II study of YL205 in China to evaluate the safety, tolerability, PK characteristics and preliminary efficacy of YL205 in the following selected patient...

Lake Mary, FLPHASE1252 participantsMediLink Therapeutics (Suzhou) Co., Ltd.

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NCT06480552Recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

The primary objectives of this trial are to: * Characterize the safety and tolerability of TEV-56278 * Determine the Recommended Phase 2 Dose (RP2D) * Evaluate antitumor activity of TEV-56278 (Part 2...

Lake Mary, FLPHASE1240 participantsTeva Branded Pharmaceutical Products R&D LLC

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NCT05732831Recruiting

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-label, dose escalation and the second part is...

Lake Mary, FLPHASE1225 participantsTango Therapeutics, Inc.

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NCT06586957Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

The goal of the Dose Escalation phase of the study is to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity to determine the preliminary recommended dose for ...

Lake Mary, FLPHASE1150 participantsNiKang Therapeutics, Inc.

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NCT06386146Recruiting

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

This study is to evaluate the efficacy and safety of JAB-30355 in adult participants with advanced solid tumors harboring TP53 Y220C mutation....

Lake Mary, FLPHASE1144 participantsJacobio Pharmaceuticals Co., Ltd.

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NCT06874335Recruiting

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

This is a Phase 1, first in human (FIH), Open-Label, Dose Escalation, Dose Expansion and Dose Optimization Study of BHV-1530 as Monotherapy and in Combination with Other Anti-Cancer Agents in Adult Pa...

Lake Mary, FLPHASE1140 participantsBiohaven Therapeutics Ltd.

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NCT04872166Recruiting

A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

This is a multicenter, open label, nonrandomized, sequential dose escalation/dose ranging, multiple dose study designed to evaluate the safety, toxicity, and PK as well as preliminary efficacy of BTX-...

Lake Mary, FLPHASE1112 participantsEdgewood Oncology Inc.

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About Advanced Solid Tumors Clinical Trials in Lake Mary

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 13 advanced solid tumors clinical trials recruiting participants in Lake Mary, FL. These studies are seeking a combined 4,648 participants. Research is being sponsored by Eli Lilly and Company, Astellas Pharma Inc, GlaxoSmithKline and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Lake Mary — FAQ

Are there advanced solid tumors clinical trials in Lake Mary?

Yes, there are 13 advanced solid tumors clinical trials currently recruiting in Lake Mary, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lake Mary?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lake Mary research site will contact you about next steps.

Are clinical trials in Lake Mary free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lake Mary studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 13 active trials in Lake Mary are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated July 23, 2026 from ClinicalTrials.gov