Lancaster, CA15 Active Studies

Rheumatoid Arthritis Clinical Trials in Lancaster, CA

Find 15 actively recruiting rheumatoid arthritis clinical trials in Lancaster, CA. Connect with local research sites and explore new treatment options.

15
Active Trials
11
Sponsors
5,079
Enrolling

Recruiting Rheumatoid Arthritis Studies in Lancaster

RecruitingLancaster, CANCT03519945

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Parti...

1,063 participants
Eli Lilly and Company
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RecruitingLancaster, CANCT07012395

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficac...

645 participants
Spyre Therapeutics, Inc.
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RecruitingLancaster, CANCT06880744

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will evaluate how safe and ef...

530 participants
AbbVie
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RecruitingLancaster, CANCT06589986

A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled, treat-through study will evaluate the efficacy and safety of Afimkibart (RO7790121) compared with placebo in participants with moderately...

400 participants
Hoffmann-La Roche
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RecruitingLancaster, CANCT05181137

A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Coli...

368 participants
Reistone Biopharma Company Limited
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RecruitingLancaster, CANCT06588855

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with mo...

350 participants
Hoffmann-La Roche
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RecruitingLancaster, CANCT05488340

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)

This is a Phase 2 superiority study of LBP-EC01, a recombinant bacteriophage cocktail, with an initial open-label 3-arm pharmacokinetic (PK) lead-in portion of 30 patients to evaluate the optimal dosi...

318 participants
Locus Biosciences
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RecruitingLancaster, CANCT06425159

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

The purpose of this study is to determine whether BHV-7000 is effective in the treatment of idiopathic generalized epilepsy with generalized tonic-clonic seizures and includes an additional open-label...

242 participants
Biohaven Therapeutics Ltd.
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RecruitingLancaster, CANCT06290934

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if GS-1427 is effective in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treate...

228 participants
Gilead Sciences
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RecruitingLancaster, CANCT03550391

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to s...

206 participants
Canadian Cancer Trials Group
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RecruitingLancaster, CANCT05588843

Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis

This is a randomized, double-blind, placebo controlled, dose-ranging Phase 2 study. The primary objective is to evaluate the efficacy and safety of SAR443122 compared to placebo in participants with m...

182 participants
Sanofi
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RecruitingLancaster, CANCT06029972

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will comp...

176 participants
Gilead Sciences
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RecruitingLancaster, CANCT06598943

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC)....

140 participants
Eli Lilly and Company
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RecruitingLancaster, CANCT06127043

A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)...

132 participants
AnaptysBio, Inc.
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RecruitingLancaster, CANCT06975722

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compare...

99 participants
Sanofi
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About Rheumatoid Arthritis Clinical Trials in Lancaster

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 15 rheumatoid arthritis clinical trials recruiting participants in Lancaster, CA. These studies are seeking a combined 5,079 participants. Research is being sponsored by Eli Lilly and Company, Spyre Therapeutics, Inc., AbbVie and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Lancaster — FAQ

Are there rheumatoid arthritis clinical trials in Lancaster?

Yes, there are 15 rheumatoid arthritis clinical trials currently recruiting in Lancaster, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lancaster?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lancaster research site will contact you about next steps.

Are clinical trials in Lancaster free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lancaster studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 15 active trials in Lancaster are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov