Lancaster, CALIFORNIA17 Active Studies

Inflammatory Bowel Disease Clinical Trials in Lancaster, CALIFORNIA

Find 17 actively recruiting inflammatory bowel disease clinical trials in Lancaster, CALIFORNIA. Connect with local research sites and explore new treatment options.

17
Active Trials
10
Sponsors
6,847
Enrolling

Recruiting Inflammatory Bowel Disease Studies in Lancaster

RecruitingLancaster, CALIFORNIANCT06430801

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1's primary hypotheses are that at least 1...

1,200 participants
Merck Sharp & Dohme LLC
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RecruitingLancaster, CALIFORNIANCT03519945

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Parti...

1,063 participants
Eli Lilly and Company
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RecruitingLancaster, CALIFORNIANCT07012395

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficac...

645 participants
Spyre Therapeutics, Inc.
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RecruitingLancaster, CALIFORNIANCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) i...

600 participants
Hoffmann-La Roche
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RecruitingLancaster, CALIFORNIANCT06880744

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will evaluate how safe and ef...

530 participants
AbbVie
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RecruitingLancaster, CALIFORNIANCT06819891

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately...

425 participants
Hoffmann-La Roche
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RecruitingLancaster, CALIFORNIANCT06589986

A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled, treat-through study will evaluate the efficacy and safety of Afimkibart (RO7790121) compared with placebo in participants with moderately...

400 participants
Hoffmann-La Roche
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RecruitingLancaster, CALIFORNIANCT05181137

A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Coli...

368 participants
Reistone Biopharma Company Limited
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RecruitingLancaster, CALIFORNIANCT06588855

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with mo...

350 participants
Hoffmann-La Roche
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RecruitingLancaster, CALIFORNIANCT06290934

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if GS-1427 is effective in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treate...

228 participants
Gilead Sciences
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RecruitingLancaster, CALIFORNIANCT06226883

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 2 active dose regimens of MORF-057 in adult study participants with moderately...

210 participants
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
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RecruitingLancaster, CALIFORNIANCT05588843

Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis

This is a randomized, double-blind, placebo controlled, dose-ranging Phase 2 study. The primary objective is to evaluate the efficacy and safety of SAR443122 compared to placebo in participants with m...

182 participants
Sanofi
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RecruitingLancaster, CALIFORNIANCT06029972

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will comp...

176 participants
Gilead Sciences
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RecruitingLancaster, CALIFORNIANCT06598943

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC)....

140 participants
Eli Lilly and Company
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RecruitingLancaster, CALIFORNIANCT06127043

A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)...

132 participants
AnaptysBio, Inc.
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RecruitingLancaster, CALIFORNIANCT06958536

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Crohn's disease. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared w...

99 participants
Sanofi
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RecruitingLancaster, CALIFORNIANCT06975722

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compare...

99 participants
Sanofi
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About Inflammatory Bowel Disease Clinical Trials in Lancaster

Inflammatory bowel disease (IBD) encompasses chronic inflammatory conditions of the gastrointestinal tract, primarily Crohn's disease and ulcerative colitis. It affects millions worldwide and can cause debilitating symptoms. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 17 inflammatory bowel disease clinical trials recruiting participants in Lancaster, CALIFORNIA. These studies are seeking a combined 6,847 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Eli Lilly and Company, Spyre Therapeutics, Inc. and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Inflammatory Bowel Disease Clinical Trials in Lancaster — FAQ

Are there inflammatory bowel disease clinical trials in Lancaster?

Yes, there are 17 inflammatory bowel disease clinical trials currently recruiting in Lancaster, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lancaster?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lancaster research site will contact you about next steps.

Are clinical trials in Lancaster free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lancaster studies also compensate for your time and travel.

What inflammatory bowel disease treatments are being tested?

The 17 active trials in Lancaster are testing new therapies including novel drugs, biologics, and treatment approaches for inflammatory bowel disease.

Data updated March 2, 2026 from ClinicalTrials.gov