4 Diffuse Large B-Cell Lymphoma Clinical Trials in Lexington, KY (2026)

Q: How do I join a clinical trial in Lexington?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you.

Recruiting Diffuse Large B-Cell Lymphoma Studies in Lexington

NCT06091865Recruiting

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with Diffuse Large B-cell Ly...

Lexington, KYPHASE3904 participantsRegeneron Pharmaceuticals

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NCT05139017Recruiting

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

The purpose of this Phase 2/3, randomized, multisite, open-label, dose confirmation, and expansion study is to evaluate the safety, and efficacy of zilovertamab vedotin (ZV) in combination with standa...

Lexington, KYPHASE2290 participantsMerck Sharp & Dohme LLC

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NCT05952024Recruiting

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBC...

Lexington, KYPHASE280 participantsAstraZeneca

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NCT06789159Recruiting

A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)

This is a Phase Ib in adult patients with relapsed or refractory EBV-positive DLBCL using daily oral dosing of VK-2019 in three dose escalation cohorts: 600 mg/day, 1200 mg/day, 1800 mg/day for 28 day...

Lexington, KYPHASE130 participantsPierluigi Porcu

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About Diffuse Large B-Cell Lymphoma Clinical Trials in Lexington

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, accounting for about 30% of cases. It is an aggressive lymphoma that grows rapidly. Treatment usually involves chemoimmunotherapy, with CAR-T cell therapy for relapsed cases.

There are currently 4 diffuse large b-cell lymphoma clinical trials recruiting participants in Lexington, KY. These studies are seeking a combined 1,304 participants. Research is being sponsored by Regeneron Pharmaceuticals, Merck Sharp & Dohme LLC, AstraZeneca and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Diffuse Large B-Cell Lymphoma Clinical Trials in Lexington — FAQ

Are there diffuse large b-cell lymphoma clinical trials in Lexington?

Yes, there are 4 diffuse large b-cell lymphoma clinical trials currently recruiting in Lexington, KY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lexington?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you about next steps.

Are clinical trials in Lexington free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lexington studies also compensate for your time and travel.

What diffuse large b-cell lymphoma treatments are being tested?

The 4 active trials in Lexington are testing new therapies including novel drugs, biologics, and treatment approaches for diffuse large b-cell lymphoma.

Data updated October 16, 2026 from ClinicalTrials.gov