Little Rock, AR6 Active Studies

Endometrial Cancer Clinical Trials in Little Rock, AR

Find 6 actively recruiting endometrial cancer clinical trials in Little Rock, AR. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
2,202
Enrolling

Recruiting Endometrial Cancer Studies in Little Rock

RecruitingLittle Rock, ARNCT06486441

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)

The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemot...

640 participants
Gilead Sciences
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RecruitingLittle Rock, ARNCT06989112

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when compared to chemotherapy (carboplatin + paclitaxel) + pembroliz...

600 participants
AstraZeneca
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RecruitingLittle Rock, ARNCT05256225

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (pac...

360 participants
National Cancer Institute (NCI)
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RecruitingLittle Rock, ARNCT05548296

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial cancer....

353 participants
Acrivon Therapeutics
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RecruitingLittle Rock, ARNCT05611931

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial carcinoma (EC), who have achieved a partial response (PR) o...

220 participants
Karyopharm Therapeutics Inc
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RecruitingLittle Rock, ARNCT05997017

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...

29 participants
Aadi Bioscience, Inc.
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About Endometrial Cancer Clinical Trials in Little Rock

Endometrial cancer begins in the lining of the uterus and is the most common gynecologic cancer. It is often detected early due to abnormal bleeding symptoms. Treatment typically involves surgery, with radiation, chemotherapy, or hormone therapy for advanced cases.

There are currently 6 endometrial cancer clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 2,202 participants. Research is being sponsored by Gilead Sciences, AstraZeneca, National Cancer Institute (NCI) and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Endometrial Cancer Clinical Trials in Little Rock — FAQ

Are there endometrial cancer clinical trials in Little Rock?

Yes, there are 6 endometrial cancer clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What endometrial cancer treatments are being tested?

The 6 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for endometrial cancer.

Data updated March 2, 2026 from ClinicalTrials.gov