Loma Linda, CALIFORNIA12 Active Studies

Rheumatoid Arthritis Clinical Trials in Loma Linda, CALIFORNIA

Find 12 actively recruiting rheumatoid arthritis clinical trials in Loma Linda, CALIFORNIA. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
2,144
Enrolling

Recruiting Rheumatoid Arthritis Studies in Loma Linda

RecruitingLoma Linda, CALIFORNIANCT05904028

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration....

600 participants
Jaeb Center for Health Research
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RecruitingLoma Linda, CALIFORNIANCT06864988

4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration...

400 participants
4D Molecular Therapeutics
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RecruitingLoma Linda, CALIFORNIANCT06143787

Effect of TXA Oral Sol 5% in Patients Treated With DOACs or VKA and Undergoing a Single or Multiple Tooth Extraction

The purpose of this study is to assess the effect of Tranexamic Acid Oral Solution 5% in patients treated with direct oral anticoagulants or vitamin K antagonists and undergoing a single or multiple t...

280 participants
Hyloris Developments
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RecruitingLoma Linda, CALIFORNIANCT04166409

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated lo...

220 participants
National Cancer Institute (NCI)
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RecruitingLoma Linda, CALIFORNIANCT04684368

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell ...

160 participants
Children's Oncology Group
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RecruitingLoma Linda, CALIFORNIANCT05099003

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse...

132 participants
National Cancer Institute (NCI)
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RecruitingLoma Linda, CALIFORNIANCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

120 participants
Bristol-Myers Squibb
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RecruitingLoma Linda, CALIFORNIANCT06100289

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

The main aim of this study is to learn how the body of a child or teenager with moderately to severely active ulcerative colitis (UC) or Crohn's disease (CD) processes vedolizumab (pharmacokinetics) g...

70 participants
Takeda
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RecruitingLoma Linda, CALIFORNIANCT03394365

Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy

The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferati...

66 participants
Pierre Fabre Medicament
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RecruitingLoma Linda, CALIFORNIANCT05287126

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years ...

36 participants
Pfizer
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RecruitingLoma Linda, CALIFORNIANCT06164587

Evaluation of Kamuvudine-8 in Subjects With Geographic Atrophy

This interventional study is a single-center, open label, 26-week study, designed to evaluate the safety and treatment efficacy of K8 in patients with geographic atrophy (GA) due to age-related macula...

30 participants
University of Kentucky
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RecruitingLoma Linda, CALIFORNIANCT07157787

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

The primary objective of this study is to evaluate the efficacy of ALXN1920 compared with placebo in participants with PMN who are at a high risk for disease progression using 24-hour urine protein cr...

30 participants
Alexion Pharmaceuticals, Inc.
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About Rheumatoid Arthritis Clinical Trials in Loma Linda

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 12 rheumatoid arthritis clinical trials recruiting participants in Loma Linda, CALIFORNIA. These studies are seeking a combined 2,144 participants. Research is being sponsored by Jaeb Center for Health Research, 4D Molecular Therapeutics, Hyloris Developments and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Loma Linda — FAQ

Are there rheumatoid arthritis clinical trials in Loma Linda?

Yes, there are 12 rheumatoid arthritis clinical trials currently recruiting in Loma Linda, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Loma Linda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Loma Linda research site will contact you about next steps.

Are clinical trials in Loma Linda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Loma Linda studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 12 active trials in Loma Linda are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov