8 Breast Cancer Clinical Trials in Los Alamitos, CA (2026)

Q: How do I join a clinical trial in Los Alamitos?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Alamitos research site will contact you.

Recruiting Breast Cancer Studies in Los Alamitos

NCT06393374Recruiting

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TP...

Los Alamitos, CAPHASE31,530 participantsMerck Sharp & Dohme LLC

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NCT06312176Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone rece...

Los Alamitos, CAPHASE31,200 participantsMerck Sharp & Dohme LLC

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NCT07085767Recruiting

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

This phase 3 clinical trial compares the efficacy and safety of palazestrant with ribociclib to letrozole and ribociclib in women and men who have not received prior systemic anti-cancer treatment for...

Los Alamitos, CAPHASE31,000 participantsOlema Pharmaceuticals, Inc.

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NCT06016738Recruiting

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

This phase 3 clinical trial compares the safety and efficacy of palazestrant (OP-1250) to the standard-of-care options of fulvestrant or an aromatase inhibitor in women and men with breast cancer whos...

Los Alamitos, CAPHASE3510 participantsOlema Pharmaceuticals, Inc.

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NCT06790693Recruiting

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

This study will evaluate the efficacy and safety of the combination of inavolisib plus a cyclin-dependent kinase 4 and 6 inhibitor (CDK4/6i) and letrozole versus placebo plus a CDK4/6i and letrozole i...

Los Alamitos, CAPHASE3450 participantsHoffmann-La Roche

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NCT07102381Recruiting

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

The purpose of this study is to see if zanidatamab is safe and effective, when combined with chemotherapy, in treating people who has Human Epidermal Growth Factor Receptor 2 (HER2)-positive, early-st...

Los Alamitos, CAPHASE2125 participantsJazz Pharmaceuticals

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NCT06764940Recruiting

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

This study is a multicenter, two-stage clinical trial to evaluate the efficacy and safety of utidelone in combination with capecitabine in patients with HER2-negative breast cancer with brain metastas...

Los Alamitos, CAPHASE2120 participantsBiostar Pharma, Inc.

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NCT04553770Recruiting

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

This phase II trial investigates how well trastuzumab deruxtecan works alone or in combination with anastrozole in treating patients with HER2 low, hormone receptor positive breast cancer. Trastuzumab...

Los Alamitos, CAPHASE288 participantsJonsson Comprehensive Cancer Center

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About Breast Cancer Clinical Trials in Los Alamitos

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Los Alamitos, CA. These studies are seeking a combined 5,023 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Olema Pharmaceuticals, Inc., Hoffmann-La Roche and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Los Alamitos — FAQ

Are there breast cancer clinical trials in Los Alamitos?

Yes, there are 8 breast cancer clinical trials currently recruiting in Los Alamitos, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Alamitos?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Alamitos research site will contact you about next steps.

Are clinical trials in Los Alamitos free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Alamitos studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Los Alamitos are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated July 19, 2026 from ClinicalTrials.gov