13 Heart Failure Clinical Trials in Los Angeles, CA (2026)

Q: How do I join a clinical trial in Los Angeles?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you.

Recruiting Heart Failure Studies in Los Angeles

NCT06008197Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricul...

Los Angeles, CAPHASE35,200 participantsColorado Prevention Center

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NCT06307652Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients with chronic HF and impaired kidney function...

Los Angeles, CAPHASE34,800 participantsAstraZeneca

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NCT06736574Recruiting

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in p...

Los Angeles, CAPHASE31,800 participantsCytokinetics

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NCT05934487Recruiting

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure...

Los Angeles, CANA1,750 participantsEndotronix, Inc.

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NCT05064709Recruiting

Assessment of CCM in HF With Higher Ejection Fraction

The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%....

Los Angeles, CANA1,500 participantsImpulse Dynamics

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NCT07069738Recruiting

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

This study will compare two different methods to pace the heart to treat heart failure including: 1. The current standard method of implanting a pacing lead in a vein on the surface of the left lower...

Los Angeles, CANA850 participantsBoston Scientific Corporation

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NCT06812533Recruiting

Alleviant ALLAY-HFrEF Study

Prospective, multicenter, randomized, sham-controlled, double blind (patient and observer), study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the A...

Los Angeles, CANA350 participantsAlleviant Medical, Inc.

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NCT05714085Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period. The primary hypothesi...

Los Angeles, CAPHASE2342 participantsMerck Sharp & Dohme LLC

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NCT06183437Recruiting

The STOP-MED CTRCD Trial

Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as...

Los Angeles, CAPHASE4335 participantsDinesh Thavendiranathan

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NCT06939751Recruiting

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circulating miRs (associated with drug doses and...

Los Angeles, CA250 participantsInova Health Care Services

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NCT05034432Recruiting

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

To investigate the effect of VTA ablation at the time of LVAD implant to see if it can reduce the incidence of VTA after surgery...

Los Angeles, CAPHASE4100 participantsUniversity of Rochester

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NCT06877169Recruiting

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

The primary purpose of this study is to evaluate the safety and efficacy of ex vivo machine perfusion with staged implantation of kidney allografts during combined heart/kidney transplantation....

Los Angeles, CANA20 participantsCedars-Sinai Medical Center

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NCT03383419Recruiting

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

This phase II, multi-center, open-label study will evaluate the safety and efficacy of utilizing HCV-positive donors for heart transplant in HCV-negative recipients treated with sofosbuvir 400 mg / ve...

Los Angeles, CAPHASE215 participantsBaylor Research Institute

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About Heart Failure Clinical Trials in Los Angeles

Heart failure is a chronic condition where the heart cannot pump blood efficiently to meet the body's needs. It affects millions of people worldwide and can result from various heart conditions. Treatment includes medications, lifestyle changes, devices, and in severe cases, heart transplant.

There are currently 13 heart failure clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 17,312 participants. Research is being sponsored by Colorado Prevention Center, AstraZeneca, Cytokinetics and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Failure Clinical Trials in Los Angeles — FAQ

Are there heart failure clinical trials in Los Angeles?

Yes, there are 13 heart failure clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What heart failure treatments are being tested?

The 13 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for heart failure.

Data updated September 4, 2026 from ClinicalTrials.gov