Los Angeles, CA7 Active Studies

Myeloproliferative Neoplasms Clinical Trials in Los Angeles, CA

Find 7 actively recruiting myeloproliferative neoplasms clinical trials in Los Angeles, CA. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
1,978
Enrolling

Recruiting Myeloproliferative Neoplasms Studies in Los Angeles

RecruitingLos Angeles, CANCT06479135

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

This clinical trial is evaluating whether addition of navtemadlin to ruxolitinib treatment will provide more clinical benefit than ruxolitinib alone for patients with Myelofibrosis who have a suboptim...

600 participants
Kartos Therapeutics, Inc.
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RecruitingLos Angeles, CANCT03165734

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia ...

399 participants
Swedish Orphan Biovitrum
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RecruitingLos Angeles, CANCT03662126

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition...

385 participants
Kartos Therapeutics, Inc.
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RecruitingLos Angeles, CANCT04576156

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

The purpose of the study is to evaluate the overall survival of participants treated with imetelstat compared to best available therapy with intermediate-2 or high-risk Myelofibrosis (MF) who are rela...

320 participants
Geron Corporation
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RecruitingLos Angeles, CANCT04176198

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or...

240 participants
Sumitomo Pharma America, Inc.
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RecruitingLos Angeles, CANCT06985147

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics...

20 participants
Disc Medicine, Inc
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RecruitingLos Angeles, CANCT05467800

Study of Canakinumab in Patients With Myelofibrosis

This is an open label, multicenter, phase 2 trial of Canakinumab in patients with primary myelofibrosis (PMF), post essential thrombocythemia/polycythemia vera related MF (Post ET/PV MF). Eligible pat...

14 participants
John Mascarenhas
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About Myeloproliferative Neoplasms Clinical Trials in Los Angeles

Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.

There are currently 7 myeloproliferative neoplasms clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 1,978 participants. Research is being sponsored by Kartos Therapeutics, Inc., Swedish Orphan Biovitrum, Geron Corporation and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myeloproliferative Neoplasms Clinical Trials in Los Angeles — FAQ

Are there myeloproliferative neoplasms clinical trials in Los Angeles?

Yes, there are 7 myeloproliferative neoplasms clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What myeloproliferative neoplasms treatments are being tested?

The 7 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.

Data updated March 2, 2026 from ClinicalTrials.gov