Los Angeles, CALIFORNIA14 Active Studies

Inflammatory Bowel Disease Clinical Trials in Los Angeles, CALIFORNIA

Find 14 actively recruiting inflammatory bowel disease clinical trials in Los Angeles, CALIFORNIA. Connect with local research sites and explore new treatment options.

14
Active Trials
8
Sponsors
5,090
Enrolling

Recruiting Inflammatory Bowel Disease Studies in Los Angeles

RecruitingLos Angeles, CALIFORNIANCT06430801

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1's primary hypotheses are that at least 1...

1,200 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CALIFORNIANCT06052059

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

The purpose of this protocol is to evaluate the efficacy of tulisokibart in participants with moderately to severely active ulcerative colitis. Study 1's primary hypotheses are that at least 1 tulisok...

1,020 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CALIFORNIANCT05781152

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pai...

900 participants
Connecticut Children's Medical Center
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RecruitingLos Angeles, CALIFORNIANCT06227910

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

396 participants
Takeda
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RecruitingLos Angeles, CALIFORNIANCT06257706

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

Transmural healing (TMH) is recognized as a potentially important measure of Crohn's disease (CD) activity but not a formal target. Observational studies suggest that TMH may be associated with better...

304 participants
Alimentiv Inc.
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RecruitingLos Angeles, CALIFORNIANCT06233461

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. The purpose of this study is to evaluate the efficacy and safety of TAK-279 versus placebo in...

268 participants
Takeda
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RecruitingLos Angeles, CALIFORNIANCT06254950

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-...

207 participants
Takeda
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RecruitingLos Angeles, CALIFORNIANCT05660746

Precise Infliximab Exposure and Pharmacodynamic Control

Approximately 3 million people in the United States are living with inflammatory bowel disease, which includes Crohn's Disease (CD). There are limited treatment options approved for use in children an...

180 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingLos Angeles, CALIFORNIANCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

120 participants
Bristol-Myers Squibb
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RecruitingLos Angeles, CALIFORNIANCT04624230

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US and EU, patients w...

120 participants
Pfizer
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RecruitingLos Angeles, CALIFORNIANCT04779320

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with vedoliz...

120 participants
Takeda
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RecruitingLos Angeles, CALIFORNIANCT06045754

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together with ustekinumab (UST) in adults with mode...

100 participants
Takeda
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RecruitingLos Angeles, CALIFORNIANCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

90 participants
Eli Lilly and Company
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RecruitingLos Angeles, CALIFORNIANCT06095128

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim...

65 participants
Takeda
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About Inflammatory Bowel Disease Clinical Trials in Los Angeles

Inflammatory bowel disease (IBD) encompasses chronic inflammatory conditions of the gastrointestinal tract, primarily Crohn's disease and ulcerative colitis. It affects millions worldwide and can cause debilitating symptoms. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 14 inflammatory bowel disease clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 5,090 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Connecticut Children's Medical Center, Takeda and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Inflammatory Bowel Disease Clinical Trials in Los Angeles — FAQ

Are there inflammatory bowel disease clinical trials in Los Angeles?

Yes, there are 14 inflammatory bowel disease clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What inflammatory bowel disease treatments are being tested?

The 14 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for inflammatory bowel disease.

Data updated March 2, 2026 from ClinicalTrials.gov