Los Angeles, CALIFORNIA14 Active Studies

Systemic Lupus Erythematosus Clinical Trials in Los Angeles, CALIFORNIA

Find 14 actively recruiting systemic lupus erythematosus clinical trials in Los Angeles, CALIFORNIA. Connect with local research sites and explore new treatment options.

14
Active Trials
10
Sponsors
4,560
Enrolling

Recruiting Systemic Lupus Erythematosus Studies in Los Angeles

RecruitingLos Angeles, CALIFORNIANCT04895241

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active...

540 participants
Biogen
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RecruitingLos Angeles, CALIFORNIANCT04961567

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active...

540 participants
Biogen
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RecruitingLos Angeles, CALIFORNIANCT05617677

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population....

490 participants
Bristol-Myers Squibb
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RecruitingLos Angeles, CALIFORNIANCT06617325

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of mo...

450 participants
UCB Biopharma SRL
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RecruitingLos Angeles, CALIFORNIANCT05126277

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult p...

420 participants
Novartis Pharmaceuticals
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RecruitingLos Angeles, CALIFORNIANCT05639114

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (s.c.) injection on top of standard-of-care (SoC)...

406 participants
Novartis Pharmaceuticals
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RecruitingLos Angeles, CALIFORNIANCT05138133

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis...

360 participants
AstraZeneca
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RecruitingLos Angeles, CALIFORNIANCT06411249

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

This is a prospective, open-label, single arm 3-year clinical study to describe the short-term and long-term efficacy and safety of belimumab in participants with autoantibody positive early SLE with ...

350 participants
GlaxoSmithKline
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RecruitingLos Angeles, CALIFORNIANCT00775476

Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease which often has debilitating and potentially life-threatening consequences. The cause of SLE is unknown and current therapies lack ...

290 participants
State University of New York - Upstate Medical University
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RecruitingLos Angeles, CALIFORNIANCT05268289

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care treatment....

240 participants
Novartis Pharmaceuticals
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RecruitingLos Angeles, CALIFORNIANCT06043440

Down Syndrome Obstructive Sleep Apnea

The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) w...

230 participants
Brigham and Women's Hospital
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RecruitingLos Angeles, CALIFORNIANCT05835310

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE...

100 participants
AstraZeneca
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RecruitingLos Angeles, CALIFORNIANCT05201469

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

74 participants
National Institute of Allergy and Infectious Diseases (NIAID)
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RecruitingLos Angeles, CALIFORNIANCT04652882

Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female participants with DSWPD....

70 participants
Vanda Pharmaceuticals
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About Systemic Lupus Erythematosus Clinical Trials in Los Angeles

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, blood cells, brain, heart, and lungs. It is characterized by periods of flares and remission. Treatment includes antimalarials, immunosuppressants, corticosteroids, and biologics like belimumab.

There are currently 14 systemic lupus erythematosus clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 4,560 participants. Research is being sponsored by Biogen, Bristol-Myers Squibb, UCB Biopharma SRL and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Systemic Lupus Erythematosus Clinical Trials in Los Angeles — FAQ

Are there systemic lupus erythematosus clinical trials in Los Angeles?

Yes, there are 14 systemic lupus erythematosus clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What systemic lupus erythematosus treatments are being tested?

The 14 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for systemic lupus erythematosus.

Data updated March 2, 2026 from ClinicalTrials.gov