Los Angeles, CALIFORNIA5 Active Studies

Triple Negative Breast Cancer Clinical Trials in Los Angeles, CALIFORNIA

Find 5 actively recruiting triple negative breast cancer clinical trials in Los Angeles, CALIFORNIA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
3,254
Enrolling

Recruiting Triple Negative Breast Cancer Studies in Los Angeles

RecruitingLos Angeles, CALIFORNIANCT05633654

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatmen...

1,514 participants
Gilead Sciences
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RecruitingLos Angeles, CALIFORNIANCT06841354

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Researchers want to know if sacituzumab tirumotecan given alone or with pembrolizumab can treat triple negative breast cancer (TNBC). The main goal of this study is to learn if people treated with sac...

1,000 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CALIFORNIANCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

The purpose of this study is to assess the efficacy and safety of iza-bren, a bi-specific antibody-drug conjugate against EGFR and HER3 with a topoisomerase inhibitor payload versus treatment of physi...

560 participants
Bristol-Myers Squibb
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RecruitingLos Angeles, CALIFORNIANCT06926920

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

The goal of this clinical study is to learn more about the study drug sacituzumab govitecan-hziy (SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNB...

100 participants
Gilead Sciences
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RecruitingLos Angeles, CALIFORNIANCT03546686

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

The purpose of this study is to determine the impact of pre-operative cryoablation, and immune checkpoint inhibition (ICI) on on 3-year Event Free Survival (EFS), in women with residual hormone recept...

80 participants
University of Texas Southwestern Medical Center
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About Triple Negative Breast Cancer Clinical Trials in Los Angeles

Triple-negative breast cancer (TNBC) lacks estrogen receptors, progesterone receptors, and excess HER2 protein, limiting targeted treatment options. It accounts for about 10-15% of breast cancers and tends to be more aggressive. Active research focuses on immunotherapy and novel drug combinations.

There are currently 5 triple negative breast cancer clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 3,254 participants. Research is being sponsored by Gilead Sciences, Merck Sharp & Dohme LLC, Bristol-Myers Squibb and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Triple Negative Breast Cancer Clinical Trials in Los Angeles — FAQ

Are there triple negative breast cancer clinical trials in Los Angeles?

Yes, there are 5 triple negative breast cancer clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What triple negative breast cancer treatments are being tested?

The 5 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for triple negative breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov