Louisville, KENTUCKY10 Active Studies

Rheumatoid Arthritis Clinical Trials in Louisville, KENTUCKY

Find 10 actively recruiting rheumatoid arthritis clinical trials in Louisville, KENTUCKY. Connect with local research sites and explore new treatment options.

10
Active Trials
10
Sponsors
2,244
Enrolling

Recruiting Rheumatoid Arthritis Studies in Louisville

RecruitingLouisville, KENTUCKYNCT05947955

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard of care (SOC) in subjects wit...

600 participants
BioAegis Therapeutics Inc.
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RecruitingLouisville, KENTUCKYNCT06072131

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Part 1: This is a 5 Arm study primarily to determine the best dose out of the two dose levels of Belinostat and Pralatrexate combined with CHOP/COP in newly diagnosed PTCL patients based on Safety for...

504 participants
Acrotech Biopharma Inc.
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RecruitingLouisville, KENTUCKYNCT06282575

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

The purpose of this study is to evaluate the efficacy and safety of Zanidatamab plus CisGem (Cisplatin and Gemcitabine) with or without the addition of a programmed death protein 1/ligand-1 (PD-1/L1) ...

286 participants
Jazz Pharmaceuticals
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RecruitingLouisville, KENTUCKYNCT06993610

Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 16 weeks (Period 1) in adults with hidradenitis suppurativa, follow...

180 participants
Zura Bio Inc
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RecruitingLouisville, KENTUCKYNCT06456580

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (RemeMG)

The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of generalized myasthenia gravis....

180 participants
RemeGen Co., Ltd.
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RecruitingLouisville, KENTUCKYNCT04462770

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

This is a multicenter, Phase 3, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of clemizole hydrochloride (EPX-100) as adjunctive therapy in children a...

150 participants
Epygenix
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RecruitingLouisville, KENTUCKYNCT06480760

Effects of Carnosine In Patients With Peripheral Arterial Disease Patients

The purpose of this study is to determine whether carnosine (a food ingredient found in chicken and red meat) supplementation (2 g) for 6 months in participants with non-claudication and claudication ...

144 participants
Shahid Baba
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RecruitingLouisville, KENTUCKYNCT07116499

A Study of K-645 in the Treatment of Multiple Migraine Attacks

This is a multicenter, randomized, double-blind, placebo-controlled, 3-period crossover study to evaluate the safety, tolerability, and efficacy of two dose levels of K-645 in the treatment of patient...

120 participants
Kallyope Inc.
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RecruitingLouisville, KENTUCKYNCT06109441

Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics

ALTB-268-201 is a Phase 2a, multicenter, single arm, multiple-dose, open-label study evaluating the efficacy and safety of ALTB-268 in subjects with moderately to severely active UC. The study consist...

50 participants
AltruBio Inc.
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RecruitingLouisville, KENTUCKYNCT04929236

Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients

Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients...

30 participants
Octapharma
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About Rheumatoid Arthritis Clinical Trials in Louisville

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 10 rheumatoid arthritis clinical trials recruiting participants in Louisville, KENTUCKY. These studies are seeking a combined 2,244 participants. Research is being sponsored by BioAegis Therapeutics Inc., Acrotech Biopharma Inc., Jazz Pharmaceuticals and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Louisville — FAQ

Are there rheumatoid arthritis clinical trials in Louisville?

Yes, there are 10 rheumatoid arthritis clinical trials currently recruiting in Louisville, KENTUCKY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Louisville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you about next steps.

Are clinical trials in Louisville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Louisville studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 10 active trials in Louisville are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov