14 Geographic Atrophy Clinical Trials in Louisville, KY (2026)

Q: How do I join a clinical trial in Louisville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you.

Recruiting Geographic Atrophy Studies in Louisville

NCT03876288Recruiting

Gastroparesis Outcome Longitudinal Database Enrolled Numerically

GOLDEN is a longitudinal database of patients with the symptoms (Sx) of gastroparesis (Gp) who were seen and recorded at the University of Louisville from 2012 and is ongoing. Patients are enrolled an...

Louisville, KY3,000 participantsUniversity of Louisville

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NCT05219110Recruiting

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

The objective of this study is to determine if early high volume intravenous fluid administration (hyperhydration) may be effective in mitigating or preventing complications of shiga toxin-producing E...

Louisville, KY1,040 participantsUniversity of Calgary

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NCT04208828Recruiting

IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy

Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serol...

Louisville, KY400 participantsUniversity of Louisville

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NCT05066217Recruiting

An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

This is a multicenter, Phase 3, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of clemizole HCL (EPX-100) as adjunctive therapy in children and adult p...

Louisville, KY260 participantsEpygenix

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NCT05482893Recruiting

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

This is a first-in-human, Phase 1/2, open-label, dose escalation and dose expansion and combination study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and prelimi...

Louisville, KY258 participantsPhanes Therapeutics

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NCT05846802Recruiting

Gastroparesis Registry 4

The Gastroparesis Registry 4 (GpR4) is an observational study of patients with symptoms of gastroparesis (Gp) and functional dyspepsia (FD) with either delayed or normal gastric emptying. To better un...

Louisville, KY250 participantsJohns Hopkins Bloomberg School of Public Health

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NCT06445972Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

This is a phase 1/2 multicenter, open-label umbrella platform study that will evaluate the safety and efficacy of sacituzumab tirumotecan (MK-2870) plus paclitaxel versus ramucirumab plus paclitaxel, ...

Louisville, KY210 participantsMerck Sharp & Dohme LLC

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NCT06469944Recruiting

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

This is a phase 1/2, multicenter, open-label umbrella platform study that will evaluate the safety and tolerability of sacituzumab tirumotecan with pembrolizumab and fluoropyrimidine chemotherapy for ...

Louisville, KY160 participantsMerck Sharp & Dohme LLC

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NCT07647328Recruiting

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

The purpose of this study is to investigate the efficacy, safety, and tolerability of camizestrant in combination with ribociclib in patients with ER+ HER2- BC who have not received any other systemic...

Louisville, KY150 participantsAstraZeneca

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NCT04661215Recruiting

Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests...

Louisville, KY150 participantsJohns Hopkins Bloomberg School of Public Health

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NCT05980455Recruiting

Study of Enterra Programming with Nocturnal Cycling in Gastroparetics

The purpose of this research study is to evaluate if different Enterra® device programming methods active during sleeping hours can maintain gastroparesis-related symptom relief and quality of life me...

Louisville, KY50 participantsEnterra Medical, Inc.

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NCT06560307Recruiting

Study of Enhanced Programming Stimulation with the Enterra® Therapy System

The purpose of this research study is to evaluate if an enhanced Enterra device programming strategy will improve symptoms associated with gastroparesis, improve symptoms in a faster amount of time, a...

Louisville, KY50 participantsEnterra Medical, Inc.

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NCT05180253Recruiting

Esophageal and Gastric Registry and Biorepository

The evaluation of the foregut, the esophagus and stomach, has come a long way over the past two decades, and continues to experience exciting discoveries in the clinical evaluation of foregut physiolo...

Louisville, KY40 participantsUniversity of Louisville

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NCT06118515Recruiting

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

This is a Phase 1 single-arm open-label study of letermovir in neonates with symptomatic congenital Cytomegalovirus (CMV) disease. There will be two groups enrolled. Group 1 will be comprised of 4 sub...

Louisville, KY12 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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About Geographic Atrophy Clinical Trials in Louisville

Geographic atrophy is the advanced form of dry age-related macular degeneration, involving progressive loss of retinal cells. It leads to enlarging blind spots in central vision. Recently approved complement inhibitor therapies can slow progression.

There are currently 14 geographic atrophy clinical trials recruiting participants in Louisville, KY. These studies are seeking a combined 6,030 participants. Research is being sponsored by University of Louisville, University of Calgary, Epygenix and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Geographic Atrophy Clinical Trials in Louisville — FAQ

Are there geographic atrophy clinical trials in Louisville?

Yes, there are 14 geographic atrophy clinical trials currently recruiting in Louisville, KY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Louisville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you about next steps.

Are clinical trials in Louisville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Louisville studies also compensate for your time and travel.

What geographic atrophy treatments are being tested?

The 14 active trials in Louisville are testing new therapies including novel drugs, biologics, and treatment approaches for geographic atrophy.

Data updated July 13, 2026 from ClinicalTrials.gov