Madison, AL8 Active Studies

Breast Cancer Clinical Trials in Madison, AL

Find 8 actively recruiting breast cancer clinical trials in Madison, AL. Connect with local research sites and explore new treatment options.

8
Active Trials
7
Sponsors
1,272
Enrolling

Recruiting Breast Cancer Studies in Madison

RecruitingMadison, ALNCT07060807

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Researchers are looking for other ways to treat breast cancer (BC) that is hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) and either unresectable locally a...

1,000 participants
Merck Sharp & Dohme LLC
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RecruitingMadison, ALNCT06247995

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

In the phase I part, to determine the recommended doses (RD) and dosing regimens of \[177Lu\]Lu-NeoB in combination with capecitabine in adult patients with gastrin releasing peptide receptor positive...

58 participants
Novartis Pharmaceuticals
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RecruitingMadison, ALNCT04762979

Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer

Patients who have histologically confirmed metastatic or unresectable (not amenable to curative therapy) breast cancer may be screened for eligibility. All patients must have HER2 negative breast canc...

44 participants
Marina N Sharifi
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RecruitingMadison, ALNCT05230810

Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.

Phase IB/II clinical trial of Alpelisb and Tucatinib in patients with PIK3CA-Mutant HER2-positive metastatic breast cancer....

40 participants
Criterium, Inc.
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RecruitingMadison, ALNCT03090165

Ribociclib and Bicalutamide in AR+ TNBC

This is an open label, multi-institutional, single arm phase II trial of ribociclib in combination with bicalutamide in advanced AR+ triple-negative breast cancer. No randomization or blinding is invo...

37 participants
Kari Wisinski
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RecruitingMadison, ALNCT05455658

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

This phase II trial studies the effect of DNA plasmid based vaccine (STEMVAC) in treating patients with patients with stage IB-III triple negative breast cancer. STEMVAC may wake up the immune system ...

33 participants
University of Washington
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RecruitingMadison, ALNCT05458674

Tucatinib+Trastuzumab+Eribulin in HER2+ MBC

The purpose of this study is to evaluate the safety and efficacy of the three-drug combination of tucatinib, trastuzumab, and eribulin in patients with de novo and recurrent unresectable metastatic HE...

30 participants
Criterium, Inc.
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RecruitingMadison, ALNCT04886531

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

Patient will be treated with neratinib, an aromatase inhibitor and trastuzumab for 24 weeks prior to surgery, following an initial 3 weeks of neratinib alone, aromatase inhibitor alone or the combinat...

30 participants
Ruth O'Regan
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About Breast Cancer Clinical Trials in Madison

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Madison, AL. These studies are seeking a combined 1,272 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Novartis Pharmaceuticals, Marina N Sharifi and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Madison — FAQ

Are there breast cancer clinical trials in Madison?

Yes, there are 8 breast cancer clinical trials currently recruiting in Madison, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Madison?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Madison research site will contact you about next steps.

Are clinical trials in Madison free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Madison studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Madison are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov