8 Breast Cancer Clinical Trials in Madison, WI (2026)

Q: How do I join a clinical trial in Madison?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Madison research site will contact you.

Recruiting Breast Cancer Studies in Madison

NCT06934239Recruiting

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

The goal of this clinical trial is to compare patient-centered outcomes when screening digital breast tomosynthesis (DBT) exams are interpreted with versus without a leading FDA-cleared artificial int...

Madison, WIPHASE4400,000 participantsJonsson Comprehensive Cancer Center

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NCT06086704Recruiting

Study of 18F-FFNP Breast PET/MRI

This clinical trial will investigate an estrogen-regulated parameter as an early measure of endocrine therapy response: progesterone receptor (PR) protein with a progestin-based radioligand, 18F-fluor...

Madison, WIPHASE253 participantsUniversity of Wisconsin, Madison

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NCT03096418Recruiting

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

The hypothesis of this study is that paclitaxel levels increase chromosomal instability (CIN) in tumors and this is lethal to tumors that have pre-existing CIN. Treatment will be administered on an ou...

Madison, WIPHASE450 participantsUniversity of Wisconsin, Madison

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NCT06295744Recruiting

Outcomes and Cosmesis With Whole Breast Irradiation and Boost

This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integ...

Madison, WINA50 participantsUniversity of Wisconsin, Madison

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NCT04886531Recruiting

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

Patient will be treated with neratinib, an aromatase inhibitor and trastuzumab for 24 weeks prior to surgery, following an initial 3 weeks of neratinib alone, aromatase inhibitor alone or the combinat...

Madison, WIPHASE230 participantsRuth O'Regan

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NCT03936478Recruiting

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of ...

Madison, WIPHASE230 participantsUniversity of Wisconsin, Madison

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NCT04573231Recruiting

Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

The purpose of this research is to determine the expression of prostate specific membrane antigen (PSMA) in human epidermal growth factor receptor 2 (HER2)-negative, androgen receptor (AR)-positive me...

Madison, WIPHASE213 participantsUniversity of Wisconsin, Madison

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NCT04174352Recruiting

FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer

Despite broad advancements in endocrine therapy for ERα+ breast cancer, resistance ultimately develops. A common driver of resistance are known ESR1 mutations that lead to constitutively active recept...

Madison, WIEARLY_PHASE112 participantsUniversity of Wisconsin, Madison

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About Breast Cancer Clinical Trials in Madison

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Madison, WI. These studies are seeking a combined 400,238 participants. Research is being sponsored by Jonsson Comprehensive Cancer Center, University of Wisconsin, Madison, Ruth O'Regan. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Madison — FAQ

Are there breast cancer clinical trials in Madison?

Yes, there are 8 breast cancer clinical trials currently recruiting in Madison, WI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Madison?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Madison research site will contact you about next steps.

Are clinical trials in Madison free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Madison studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Madison are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated July 18, 2026 from ClinicalTrials.gov