Melbourne, FL11 Active Studies

Pulmonary Hypertension Clinical Trials in Melbourne, FL

Find 11 actively recruiting pulmonary hypertension clinical trials in Melbourne, FL. Connect with local research sites and explore new treatment options.

11
Active Trials
10
Sponsors
2,657
Enrolling

Recruiting Pulmonary Hypertension Studies in Melbourne

RecruitingMelbourne, FLNCT03075696

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

This is a Phase I/II, multicenter, open-label, dose-escalation study designed to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of a novel T-Cell bispecific (TCB), glofitamab, a...

920 participants
Hoffmann-La Roche
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RecruitingMelbourne, FLNCT04077723

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

This is a phase I/II, open-label, dose-escalation study designed to evaluate the safety, tolerability, and efficacy of englumafusp alfa (RO7227166) in participants with relapsed/refractory Non-Hodgkin...

498 participants
Hoffmann-La Roche
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RecruitingMelbourne, FLNCT04521231

A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

The Phase I part of the study aims to evaluate the safety, efficacy, and tolerability of subcutaneous (SC) blinatumomab for treatment of Relapsed or Refractory B cell Precursor Acute Lymphoblastic Leu...

281 participants
Amgen
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RecruitingMelbourne, FLNCT05145127

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

Study B7841007 is an open-label extension study to assess the long-term safety, tolerability, and efficacy of prophylaxis treatment with marstacimab in participants who did not require "Early Terminat...

245 participants
Pfizer
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RecruitingMelbourne, FLNCT06542250

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

This is a Phase I/II study designed to evaluate if experimental T cell engaging antibody targeting CD20 AZD5492 is safe, tolerable and efficacious in participants with Relapsed or Refractory B-Cell Ma...

174 participants
AstraZeneca
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RecruitingMelbourne, FLNCT06514794

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a ther...

125 participants
Wugen, Inc.
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RecruitingMelbourne, FLNCT05643742

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX112â„¢ in subjects with relapsed or refractory B-cell malignancies....

120 participants
CRISPR Therapeutics AG
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RecruitingMelbourne, FLNCT06854653

A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL

This is an open-label, phase 2 randomized study to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmadynamics (PD), of PTX-100 monotherapy at 500 or 1000 mg/m2 in patients with relapsed/r...

115 participants
Prescient Therapeutics, Ltd.
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RecruitingMelbourne, FLNCT05888493

A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma

This trial will compare tisagenlecleucel to standard of care in adult participants with relapsed or refractory (r/r) follicular lymphoma....

108 participants
Novartis Pharmaceuticals
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RecruitingMelbourne, FLNCT06185764

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of VX-670 at different single and multiple doses in participants with DM1....

36 participants
Vertex Pharmaceuticals Incorporated
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RecruitingMelbourne, FLNCT06003387

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

The purpose of this study is to assess the risk of bleeding due to failure of expected pharmacological action of CSL222 in adults with severe or moderately severe hemophilia B with detectable pretreat...

35 participants
CSL Behring
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About Pulmonary Hypertension Clinical Trials in Melbourne

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 11 pulmonary hypertension clinical trials recruiting participants in Melbourne, FL. These studies are seeking a combined 2,657 participants. Research is being sponsored by Hoffmann-La Roche, Amgen, Pfizer and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Melbourne — FAQ

Are there pulmonary hypertension clinical trials in Melbourne?

Yes, there are 11 pulmonary hypertension clinical trials currently recruiting in Melbourne, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Melbourne?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Melbourne research site will contact you about next steps.

Are clinical trials in Melbourne free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Melbourne studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 11 active trials in Melbourne are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov