19 Prostate Cancer Clinical Trials in Miami, TX (2026)

Q: How do I join a clinical trial in Miami?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Miami research site will contact you.

Recruiting Prostate Cancer Studies in Miami

NCT06136624Recruiting

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

This is a phase 3, randomized, open-label study of opevesostat compared to alternative abiraterone acetate or enzalutamide in participants with metastatic castration-resistant prostate cancer (mCRPC) ...

Miami, TX1,310 participantsMerck Sharp & Dohme LLC

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NCT06855277Recruiting

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

The purpose of this study is to determine whether \[225Ac\]Ac-PSMA-617 (AAA817), given for up to 6 cycles at a dose of 10 Megabecquerel (MBq) +/- 10%, plus androgen receptor pathway inhibitor (ARPI), ...

Miami, TX940 participantsNovartis Pharmaceuticals

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NCT07611110Recruiting

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

The intention of the study is to demonstrate superiority of AZD2265 relative to standard of care treatments by assessment of radiographic progression-free survival (rPFS) and overall survival (OS) in ...

Miami, TX670 participantsAstraZeneca

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NCT06520345Recruiting

The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

The purpose of this study is to evaluate the efficacy and safety of 177Lu-TLX591 in patients with metastatic castration-resistant prostate cancer who have progressed following treatment with Androgen ...

Miami, TX520 participantsTelix Pharmaceuticals (Innovations) Pty Limited

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NCT06056830Recruiting

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

The aim for this study is to assess the diagnostic performance of 64Cu-SAR-bisPSMA PET to detect regional nodal metastases....

Miami, TX383 participantsClarity Pharmaceuticals Ltd

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NCT06353386Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Substudy 01A is part of a larger research study that is testing experimental treatments for metastatic castration-resistant prostate cancer (mCRPC). The larger study is the umbrella study (U01). The ...

Miami, TX220 participantsMerck Sharp & Dohme LLC

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NCT07590934Recruiting

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of multiple anti-cancer agents in participants with metastatic prost...

Miami, TX152 participantsAstraZeneca

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NCT02997709Recruiting

Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients

The purpose of this research study is to learn about: 1) How standard radiation treatment to prostate (primary radiotherapy) or the pelvis after prostatectomy (postoperative radiotherapy) may cause ch...

Miami, TX144 participantsUniversity of Miami

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NCT07103018Recruiting

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

Study K36-MCRPC-001 is the first in human clinical trial testing KTX-2001 alone and with darolutamide in men with metastatic castration-resistant prostate cancer. The study aims to assess whether the ...

Miami, TX144 participantsK36 Therapeutics, Inc.

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NCT07581184Recruiting

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

This is a Phase 1b, multi-center, open-label study to evaluate the safety, tolerability, dosimetry, and pharmacokinetics (PK) of \[64Cu\]Cu-AKY-2519 and/or \[225Ac\]Ac-AKY-2519, as well as the prelimi...

Miami, TX138 participantsAktis Oncology, Inc.

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NCT06879041Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275....

Miami, TX136 participantsAstraZeneca

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NCT06111313Recruiting

The University of Miami Adapt (UAdapt) Trial

The purpose of this prostate cancer research study is to investigate: 1. For early-stage patients, the use of a single session of high dose stereotactic body radiotherapy (SBRT) delivered to the tumo...

Miami, TX130 participantsUniversity of Miami

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NCT06785636Recruiting

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

This is a dose-finding study to assess the safety and preliminary antitumor activity of Pocenbrodib alone or with Abiraterone acetate, Olaparib or 177Lu-PSMA-617 in patients with metastatic castration...

Miami, TX120 participantsPathos AI, Inc.

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NCT06533644Recruiting

A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

The primary purpose of this study is to evaluate the safety, tolerability, and efficacy of SYNC-T Therapy SV-102 and to identify the maximum tolerated dose (MTD) and/or selected dose for phase 2b stud...

Miami, TX91 participantsSyncromune, Inc.

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NCT05413850Recruiting

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

To determine the dose, safety, radiation dosimetry and efficacy of 177Lu-rhPSMA-10.1 in participants with PSMA-expressing metastatic castrate resistant prostate cancer....

Miami, TX82 participantsBlue Earth Therapeutics Ltd

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NCT07455903Recruiting

Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT

The purpose of this research study is to test the efficacy of ADT on prostate-specific membrane antigen (PSMA), a marker of prostate cancer, before and after scheduled ADT. Follow up will be 48 months...

Miami, TX50 participantsBaptist Health South Florida

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NCT06392295Recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer

The purpose of this prostate cancer research study is to learn about: 1. Improving control of prostate cancer using radiation therapy, delivered to the para-aortic and pelvic lymph nodes, in addition...

Miami, TX34 participantsUniversity of Miami

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NCT06487507Recruiting

Metabolic Impact and Compliance of Controlled, Varying, Mediterranean Diets in Pre-Surgical Prostate Cancer Populations (PROVISIONS)

The study aims to investigate whether following a controlled Mediterranean-style diet prior to robotic-assisted radical prostatectomy surgery in patients diagnosed with prostate cancer affects fasting...

Miami, TX20 participantsUniversity of Miami

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NCT06906471Recruiting

A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS

A Single-Arm, blinded, fluorescent PSMA histopathology trial of AS1986NS...

Miami, TX10 participantsAntelope Surgical Solutions, Inc

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About Prostate Cancer Clinical Trials in Miami

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 19 prostate cancer clinical trials recruiting participants in Miami, TX. These studies are seeking a combined 5,294 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Novartis Pharmaceuticals, AstraZeneca and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Miami — FAQ

Are there prostate cancer clinical trials in Miami?

Yes, there are 19 prostate cancer clinical trials currently recruiting in Miami, TX. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Miami?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Miami research site will contact you about next steps.

Are clinical trials in Miami free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Miami studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 19 active trials in Miami are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated July 13, 2026 from ClinicalTrials.gov