Minneapolis, MINNESOTA24 Active Studies

Ankylosing Spondylitis Clinical Trials in Minneapolis, MINNESOTA

Find 24 actively recruiting ankylosing spondylitis clinical trials in Minneapolis, MINNESOTA. Connect with local research sites and explore new treatment options.

24
Active Trials
22
Sponsors
8,408
Enrolling

Recruiting Ankylosing Spondylitis Studies in Minneapolis

RecruitingMinneapolis, MINNESOTANCT05931276

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

The investigators aim to determine, using a point-of-care randomized controlled trial design, if hemodialysis patients, who are randomized to metoprolol succinate (a dialyzable, beta-1 selective beta ...

2,540 participants
VA Office of Research and Development
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RecruitingMinneapolis, MINNESOTANCT06422689

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care

ANCHOR is a prospective, multi-center, phase IV, interventional, single-arm, open-label study of 2,000 adult participants with symptomatic asthma requiring the use of rescue therapy aimed to compare t...

2,000 participants
AstraZeneca
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RecruitingMinneapolis, MINNESOTANCT06731478

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

This clinical trial is designed to assess the efficacy and safety of the triplet combination of trastuzumab deruxtecan (ENHERTU, T-DXd, DS-8201a) plus a fluoropyrimidine plus pembrolizumab versus stan...

726 participants
Daiichi Sankyo
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RecruitingMinneapolis, MINNESOTANCT06388733

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

The goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). T...

450 participants
Ivy Brain Tumor Center
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RecruitingMinneapolis, MINNESOTANCT06075953

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

The goal of this trial is to see if active surveillance monitoring and hormonal therapy in patients diagnosed with ductal cell carcinoma in situ (DCIS), an early stage of breast cancer, can be an effe...

400 participants
QuantumLeap Healthcare Collaborative
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RecruitingMinneapolis, MINNESOTANCT06901505

To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

This is a multi-center, randomized (1:1), open-label, active-controlled, pragmatic study of the efficacy of vadadustat administered three times a week compared to standard of care erythropoiesis-stimu...

350 participants
Akebia Therapeutics
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RecruitingMinneapolis, MINNESOTANCT04665206

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once daily in patients wit...

336 participants
Vivace Therapeutics, Inc
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RecruitingMinneapolis, MINNESOTANCT05082519

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with resistance to chemotherapy in patients w...

240 participants
Etan Orgel
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RecruitingMinneapolis, MINNESOTANCT06032065

SMART Exercise for PAD

Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lowe...

210 participants
Northwestern University
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RecruitingMinneapolis, MINNESOTANCT04794530

The COCOA-PAD II Trial

Among people with peripheral artery disease (PAD) age 55 and older, the investigators will test the hypothesis that PAD participants randomized to cocoa flavanols will have greater improvement or less...

190 participants
Northwestern University
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RecruitingMinneapolis, MINNESOTANCT05267626

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

This is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007 in patients with advanced solid tumors. AU-007 will be adminis...

159 participants
Aulos Bioscience, Inc.
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RecruitingMinneapolis, MINNESOTANCT06712823

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

The purpose of this study is to evaluate the long-term safety, tolerability, and efficacy of atumelnant (CRN04894)....

150 participants
Crinetics Pharmaceuticals Inc.
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RecruitingMinneapolis, MINNESOTANCT05995353

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This study will assess the pharmacokinetics, ...

110 participants
AbbVie
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RecruitingMinneapolis, MINNESOTANCT06332534

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms includ...

110 participants
AbbVie
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RecruitingMinneapolis, MINNESOTANCT05848687

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets...

90 participants
Tanja Andrea Gruber
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RecruitingMinneapolis, MINNESOTANCT05003986

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and tablets, and assess changes in proteinuria after once-daily dosing over 108 weeks....

67 participants
Travere Therapeutics, Inc.
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RecruitingMinneapolis, MINNESOTANCT07126262

A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months

The purpose of this study is to evaluate the safety and efficacy of daily administration of vosoritide in participants with HCH aged 0 to \< 36 months over a 52-week period....

60 participants
BioMarin Pharmaceutical
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RecruitingMinneapolis, MINNESOTANCT05092347

A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA)

The purpose of this study is to determine whether vonsetamig will safely decrease anti-HLA antibodies to allow for kidney transplantation. Vonsetamig is being studied for treatment of patients in nee...

56 participants
Regeneron Pharmaceuticals
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RecruitingMinneapolis, MINNESOTANCT02583672

Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)

The purpose of this study is to measure levels of blood and brain chemicals related to oxidative stress and inflammation in healthy volunteers and individuals with Type 1 Gaucher disease (GD1) to see ...

50 participants
University of Minnesota
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RecruitingMinneapolis, MINNESOTANCT04523727

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

This study will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney disease (CKD)....

45 participants
Keryx Biopharmaceuticals
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RecruitingMinneapolis, MINNESOTANCT05582993

A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

The main aim of the study is to evaluate the effectiveness of prophylaxis with vonicog alfa (recombinant von Willebrand factor \[rVWF\]) in children. This study will enroll those participants who have...

24 participants
Takeda
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RecruitingMinneapolis, MINNESOTANCT06858397

A proof-of Concept Study to Assess Safety and Tolerability of HM15421/GC1134A in Patients With Fabry Disease

This Phase 1/2 first-in-human (FIH) study is designed to evaluate the safety, tolerability, pharmacokinetics (PK), and efficacy of HM15421 in patients with FD....

18 participants
GC Biopharma Corp
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RecruitingMinneapolis, MINNESOTANCT05456880

BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease

This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating the safety and efficacy of the administration of autologous base edited CD34+ HSPCs (BEAM-101) in patients with severe SCD...

15 participants
Beam Therapeutics Inc.
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RecruitingMinneapolis, MINNESOTANCT06270316

Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease

The main goals of this clinical study are to characterize safety and PK/PD of AMT-191 i.e. if drug doses used in the study are safe and tolerable and to understand how it acts in the body of people wi...

12 participants
UniQure Biopharma B.V.
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About Ankylosing Spondylitis Clinical Trials in Minneapolis

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 24 ankylosing spondylitis clinical trials recruiting participants in Minneapolis, MINNESOTA. These studies are seeking a combined 8,408 participants. Research is being sponsored by VA Office of Research and Development, AstraZeneca, Daiichi Sankyo and 19 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Minneapolis — FAQ

Are there ankylosing spondylitis clinical trials in Minneapolis?

Yes, there are 24 ankylosing spondylitis clinical trials currently recruiting in Minneapolis, MINNESOTA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Minneapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Minneapolis research site will contact you about next steps.

Are clinical trials in Minneapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Minneapolis studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 24 active trials in Minneapolis are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov