14 Parkinsons Disease Clinical Trials in Minneapolis, MN (2026)

Q: How do I join a clinical trial in Minneapolis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Minneapolis research site will contact you.

Recruiting Parkinsons Disease Studies in Minneapolis

NCT06464029Recruiting

Pathways Mediating Impaired Postural Control in Parkinson's Disease

The purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to sp...

Minneapolis, MN160 participantsUniversity of Minnesota

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NCT06405334Recruiting

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains qu...

Minneapolis, MN100 participantsVA Office of Research and Development

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NCT05568199Recruiting

Udall Project 1 Aim 4

By defining the strength and direction of connectivity patterns at rest and during movement across the basal ganglia-thalamocortical (BGTC) network we will characterize the role of individual circuits...

Minneapolis, MN100 participantsUniversity of Minnesota

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NCT06506058Recruiting

Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease

Currently, there is a lack of comprehensive knowledge about the role of vestibulospinal drive and cortical activity during self-initiated movement transitions in older adults and people with PD (both ...

Minneapolis, MNNA75 participantsUniversity of Minnesota

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NCT07226284Recruiting

Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease

This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck ...

Minneapolis, MNNA75 participantsUniversity of Minnesota

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NCT05893186Recruiting

Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder

Sixty patients will be enrolled in this study who are treated for Parkinson's disease (PD) with bilateral deep brain stimulation of subthalamic nucleus (STN) or globus pallidus (GP), who have a pre- o...

Minneapolis, MNEARLY_PHASE160 participantsUniversity of Minnesota

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NCT05656586Recruiting

Udall Project 2 Aim 2A&C

This protocol will leverage the novel (on-label, FDA-approved) local field potential measuring capability of the Medtronic Percept™ PC or RC DBS system to study the effects of globus pallidus internus...

Minneapolis, MN36 participantsUniversity of Minnesota

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NCT05934747Recruiting

Aim 3 Particle Swarm Optimization PIGD

In Parkinson's disease (PD) patients undergoing standard-of-care Deep Brain Stimulation (DBS) therapy, to compare the effect on Parkinson's symptoms of two different neurostimulator settings designed ...

Minneapolis, MNNA30 participantsUniversity of Minnesota

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NCT05658302Recruiting

Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

This study will help us better understand how the brain works in people with Parkinson's disease (PD). PD is a brain disease that gets worse over time, and affects over 10 million people world-wide. A...

Minneapolis, MN30 participantsUniversity of Minnesota

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NCT03984643Recruiting

Algorithms for Programming DBS Systems for ET

Deep brain stimulation (DBS) targeting the Vim thalamus (ventralis intermedius nucleus) is an FDA-approved neuromodulation therapy for treating postural and action tremor in individuals with essential...

Minneapolis, MNNA25 participantsUniversity of Minnesota

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NCT06692920Recruiting

Characterizing the Pathophysiological Role of the Pallido-thalamocortical Motor Pathway in Parkinson's Disease.

When a patient gets DBS surgery, the neurosurgeon makes a hole in the skull through which they can put the DBS lead down in deep parts of the brain that help control movement. For this study, research...

Minneapolis, MNNA25 participantsUniversity of Minnesota

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NCT05557864Recruiting

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used ...

Minneapolis, MNNA24 participantsUniversity of Minnesota

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NCT05897775Recruiting

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses differen...

Minneapolis, MNPHASE123 participantsUniversity of Minnesota

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NCT06998303Recruiting

Imaging Core Aim 2, and Udall Project 2 Aim 2

More than one million people in the United States have Parkinson's disease (PD) and the prevalence is expected to double by 2040. Over 60% of these individuals will develop debilitating postural insta...

Minneapolis, MNNA20 participantsUniversity of Minnesota

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About Parkinsons Disease Clinical Trials in Minneapolis

Parkinson's disease is a progressive nervous system disorder that affects movement, causing tremors, stiffness, and difficulty with balance. It results from the loss of dopamine-producing neurons in the brain. Treatment includes medications, deep brain stimulation, and emerging therapies targeting disease modification.

There are currently 14 parkinsons disease clinical trials recruiting participants in Minneapolis, MN. These studies are seeking a combined 783 participants. Research is being sponsored by University of Minnesota, VA Office of Research and Development. Clinical trial participation is free and participants receive study-related medical care at no cost.

Parkinsons Disease Clinical Trials in Minneapolis — FAQ

Are there parkinsons disease clinical trials in Minneapolis?

Yes, there are 14 parkinsons disease clinical trials currently recruiting in Minneapolis, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Minneapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Minneapolis research site will contact you about next steps.

Are clinical trials in Minneapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Minneapolis studies also compensate for your time and travel.

What parkinsons disease treatments are being tested?

The 14 active trials in Minneapolis are testing new therapies including novel drugs, biologics, and treatment approaches for parkinsons disease.

Data updated July 17, 2026 from ClinicalTrials.gov