12 Prostate Cancer Clinical Trials in Minneapolis, MN (2026)

Q: How do I join a clinical trial in Minneapolis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Minneapolis research site will contact you.

Recruiting Prostate Cancer Studies in Minneapolis

NCT04787744Recruiting

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-...

Minneapolis, MNPHASE2464 participantsVA Office of Research and Development

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NCT05413421Recruiting

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

The purpose of this study is to establish the safety and preliminary antitumor activity of ORIC-944 as a single agent and in combinations with ARPIs in patients with metastatic prostate cancer....

Minneapolis, MNPHASE1275 participantsORIC Pharmaceuticals

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NCT06014255Recruiting

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

This study evaluates the efficacy, anti-tumor effect, and immunogenicity of neoadjuvant enoblituzumab given before radical prostatectomy. Patients will be randomized to enoblituzumab for a total of 12...

Minneapolis, MNPHASE2219 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT06217822Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Researchers are looking for a better way to treat participants who have metastatic castration-resistant prostate cancer (mCRPC). mCRPC is a cancer of the prostate (male reproductive gland found below...

Minneapolis, MNPHASE1198 participantsBayer

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NCT07285694Recruiting

AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

This is a multi-center, open-label Phase 1/2 trial evaluating the safety and efficacy of AB-3028 in subjects with metastatic castration resistant prostate cancer (mCRPC)....

Minneapolis, MNPHASE1190 participantsArsenal Biosciences, Inc.

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NCT07590934Recruiting

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of multiple anti-cancer agents in participants with metastatic prost...

Minneapolis, MNPHASE1152 participantsAstraZeneca

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NCT04363164Recruiting

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

Asymptomatic men without pain due to prostate cancer progressing with metastatic CRPC after treatment with combination or sequential ADT + Abi will be treated on a randomized, open label study to dete...

Minneapolis, MNPHASE2150 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT06844383Recruiting

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

The purpose of this study is to find out whether talazoparib in combination with enzalutamide or talazoparib alone delays cancer progression in people with metastatic castration-resistant prostate can...

Minneapolis, MNPHASE2126 participantsProstate Cancer Clinical Trials Consortium

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NCT04038502Recruiting

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

This is an unblinded, randomized clinical study comparing the efficacy of DNA damaging chemotherapy using carboplatin, to standard of care therapy for patients who have metastatic castrate resistant p...

Minneapolis, MNPHASE2100 participantsVA Office of Research and Development

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NCT06801236Recruiting

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

This is an open label, phase I, multi-center study aiming to assess the safety and tolerability in patients with metastatic castration resistant prostate cancer (mCRPC)....

Minneapolis, MNPHASE167 participantsAcerand Therapeutics (Hong Kong) Limited

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NCT07140900Recruiting

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

The main objective of the trial is to evaluate the safety and tolerability of xaluritamig in combination with darolutamide or abiraterone....

Minneapolis, MNPHASE160 participantsAmgen

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NCT06228053Recruiting

Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer

The goal of this clinical trial is to study the combination of SX-682 plus enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC) who have failed abiraterone....

Minneapolis, MNPHASE253 participantsSyntrix Biosystems, Inc.

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About Prostate Cancer Clinical Trials in Minneapolis

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 12 prostate cancer clinical trials recruiting participants in Minneapolis, MN. These studies are seeking a combined 2,054 participants. Research is being sponsored by VA Office of Research and Development, ORIC Pharmaceuticals, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Minneapolis — FAQ

Are there prostate cancer clinical trials in Minneapolis?

Yes, there are 12 prostate cancer clinical trials currently recruiting in Minneapolis, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Minneapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Minneapolis research site will contact you about next steps.

Are clinical trials in Minneapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Minneapolis studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 12 active trials in Minneapolis are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated July 18, 2026 from ClinicalTrials.gov