Naples, FL4 Active Studies

Rheumatoid Arthritis Clinical Trials in Naples, FL

Find 4 actively recruiting rheumatoid arthritis clinical trials in Naples, FL. Connect with local research sites and explore new treatment options.

4
Active Trials
4
Sponsors
1,336
Enrolling

Recruiting Rheumatoid Arthritis Studies in Naples

RecruitingNaples, FLNCT06323928

A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments

The purpose of this trial is to determine which doses of Lu AG09222 are recommended to help prevent migraines. People who join this trial have already tried 1 to 4 other available medications to preve...

845 participants
H. Lundbeck A/S
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RecruitingNaples, FLNCT06254950

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-...

207 participants
Takeda
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RecruitingNaples, FLNCT06393712

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

The purpose of the study is to evaluate the effect of ALN-APP on measures of CAA disease progression and to characterize the safety, tolerability, and pharmacodynamics (PD) of ALN-APP in adult patient...

200 participants
Alnylam Pharmaceuticals
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RecruitingNaples, FLNCT05731128

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

The protocol of this Phase 2 clinical trial consists of a double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of dupilumab in participants with mode...

84 participants
Sanofi
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About Rheumatoid Arthritis Clinical Trials in Naples

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 4 rheumatoid arthritis clinical trials recruiting participants in Naples, FL. These studies are seeking a combined 1,336 participants. Research is being sponsored by H. Lundbeck A/S, Takeda, Alnylam Pharmaceuticals and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Naples — FAQ

Are there rheumatoid arthritis clinical trials in Naples?

Yes, there are 4 rheumatoid arthritis clinical trials currently recruiting in Naples, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Naples?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Naples research site will contact you about next steps.

Are clinical trials in Naples free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Naples studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 4 active trials in Naples are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov