13 Heart Failure Clinical Trials in New Haven, CT (2026)

Q: How do I join a clinical trial in New Haven?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New Haven research site will contact you.

Recruiting Heart Failure Studies in New Haven

NCT04237701Recruiting

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System....

New Haven, CT40,000 participantsYale University

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NCT06933875Recruiting

Promoting Palliative Care for People With Heart Failure

This project will develop and test a novel clinical decision support tool (CDS) that encourages timely referral to palliative care for people hospitalized with heart failure. This intervention will in...

New Haven, CTNA2,260 participantsYale University

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NCT06526988Recruiting

Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure

An increasing number of guideline-directed medical therapies (GDMT) have been developed for patients with chronic heart failure with reduced ejection fraction (HFrEF). When used in combination at reco...

New Haven, CTNA2,200 participantsUniversity of Colorado, Denver

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NCT05650658Recruiting

Left vs Left Randomized Clinical Trial

The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failur...

New Haven, CTNA2,136 participantsBaylor College of Medicine

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NCT07273838Recruiting

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

The overall objective of this study is to determine whether the addition of SGLT2 inhibitors to usual care in hospitalized patients with heart failure associated acute kidney injury is safe and effica...

New Haven, CTPHASE2130 participantsYale University

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NCT04551560Recruiting

Stress and Congestive Heart Failure

The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF....

New Haven, CTNA112 participantsYale University

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NCT05323487Recruiting

Mechanisms of Diuretic Resistance in Heart Failure, Aim 1

This study will employ a randomized order, double-blind, repeated measures dose ranging design. This design was chosen in order to generate multiple within-subject serial loop diuretic dose response e...

New Haven, CTPHASE175 participantsYale University

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NCT04438213Recruiting

Ertugliflozin in Chronic Heart Failure

The purpose of this study is to determine the effects on heart failure signs and symptoms of the use of either ertugliflozin, metolazone or placebo, in conjunction with intravenous loop diuretic use i...

New Haven, CTPHASE260 participantsYale University

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NCT06209359Recruiting

Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

Randomized double-blind placebo-controlled crossover study design...

New Haven, CTPHASE150 participantsYale University

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NCT05753059Recruiting

Mechanisms of Diuretic Resistance in Heart Failure, Aim 2

Randomized placebo-controlled, double-blind, double-dummy, crossover design testing combinations placebo/placebo, bendroflumethiazide/placebo, amiloride/placebo, and bendroflumethiazide/amiloride adde...

New Haven, CTPHASE150 participantsYale University

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NCT06671015Recruiting

A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure

This prospective, open-label randomized controlled pilot trial will enroll participants at the Yale New Haven Hospital. Patients with systolic heart failure, defined as an ejection fraction ≤40%, who ...

New Haven, CTNA50 participantsYale University

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NCT07281014Recruiting

Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing

The purpose of this research study is to understand the biology related to the potential shortcomings of existing anti-aldosterone therapy....

New Haven, CTPHASE420 participantsYale University

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NCT06872645Recruiting

Exploring Water-free Sodium Storage

The overarching goal of this proposal is to definitively establish if acute water free Na storage and release occurs, if the amount stored/released is of a quantity that is physiologically relevant, a...

New Haven, CTNA10 participantsYale University

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About Heart Failure Clinical Trials in New Haven

Heart failure is a chronic condition where the heart cannot pump blood efficiently to meet the body's needs. It affects millions of people worldwide and can result from various heart conditions. Treatment includes medications, lifestyle changes, devices, and in severe cases, heart transplant.

There are currently 13 heart failure clinical trials recruiting participants in New Haven, CT. These studies are seeking a combined 47,153 participants. Research is being sponsored by Yale University, University of Colorado, Denver, Baylor College of Medicine. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Failure Clinical Trials in New Haven — FAQ

Are there heart failure clinical trials in New Haven?

Yes, there are 13 heart failure clinical trials currently recruiting in New Haven, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New Haven?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New Haven research site will contact you about next steps.

Are clinical trials in New Haven free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New Haven studies also compensate for your time and travel.

What heart failure treatments are being tested?

The 13 active trials in New Haven are testing new therapies including novel drugs, biologics, and treatment approaches for heart failure.

Data updated July 19, 2026 from ClinicalTrials.gov