23 Crohns Disease Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Crohns Disease Studies in New York

NCT06651281Recruiting

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Researchers want to learn more about tulisokibart (also known as MK-7240) in an extension study. Tulisokibart is a medicine designed to treat active, moderate to severe Crohn's disease (CD) and ulcera...

New York, NYPHASE31,380 participantsMerck Sharp & Dohme LLC

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NCT07184944Recruiting

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

This is a multicenter, randomized, double-blind, placebo-controlled, maintenance, Phase 3 study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Croh...

New York, NYPHASE3751 participantsSanofi

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NCT03256240Recruiting

Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial. Patients with Cro...

New York, NYNA600 participantsWeill Medical College of Cornell University

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NCT07577843Recruiting

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active Crohn'...

New York, NYPHASE3460 participantsJanssen Research & Development, LLC

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NCT06266663Recruiting

Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease

Optimizing health related-quality of life (HRQoL) for patients with inflammatory bowel disease (IBD), who often experience a relapsing disease course, is an essential component of care. Improving IBD ...

New York, NY400 participantsMontefiore Medical Center

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NCT06227910Recruiting

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

New York, NYPHASE3396 participantsTakeda

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NCT06533228Recruiting

Helmsley 3.0: Abbreviated MRE

The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in childre...

New York, NY300 participantsChildren's Hospital Medical Center, Cincinnati

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NCT06750731Recruiting

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

The goal of this observational study is to assess the feasibility and effectiveness of a remote monitoring digital health system on adherence, clinical outcomes, and healthcare utilization in patients...

New York, NY200 participantsMercy Medical Center

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NCT06512597Recruiting

Behavioral Therapy for Crohn's Disease

People living with Crohn's disease (CD) experience psychological and emotional symptoms, in addition to known chronic and disabling physical symptoms, which prevent them from living their life to the ...

New York, NYNA170 participantsIcahn School of Medicine at Mount Sinai

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NCT06309017Recruiting

Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease

This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing elective or emergent resection surgery fo...

New York, NYNA150 participantsNYU Langone Health

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NCT04844606Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

New York, NYPHASE3150 participantsEli Lilly and Company

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NCT06274554Recruiting

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 the...

New York, NYPHASE3120 participantsWeill Medical College of Cornell University

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NCT05923073Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants with Crohn's Disease (CD) at the end of maintenance therapy (Week 52) among partic...

New York, NYPHASE3120 participantsJanssen Research & Development, LLC

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NCT06631586Recruiting

Standardized Microbiota Transplant Therapy in Crohn's Disease

Crohn's disease (CD) develops because of a disruption of homeostasis between the gut microbiota and the host immune system resulting in excessive inflammation in the intestinal tract. Current drug the...

New York, NYPHASE2120 participantsUniversity of Minnesota

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NCT05995353Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This study will assess the pharmacokinetics, ...

New York, NYPHASE3110 participantsAbbVie

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NCT06332534Recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms includ...

New York, NYPHASE3110 participantsAbbVie

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NCT05509777Recruiting

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

New York, NYPHASE390 participantsEli Lilly and Company

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NCT06976853Recruiting

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

The purpose of this research study is to evaluate what type of treatment will be beneficial for people with Crohn's disease and difficult to treat inflammation in the small bowel. Current therapies ar...

New York, NYPHASE260 participantsWashington University School of Medicine

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NCT03219359Recruiting

Autologous Stem Cell Transplant for Crohn's Disease

Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant complications and discomfort in the stomach and intestines. Crohn's disease is a debilitating, incurable disease of im...

New York, NYPHASE250 participantsAaron Etra

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NCT06001450Recruiting

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bo...

New York, NY46 participantsIcahn School of Medicine at Mount Sinai

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NCT06918808Recruiting

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

This is a double-blind, randomized, placebo-controlled, sequential cohort, ascending dose clinical trial to evaluate the safety and determine the efficacy of ascending doses of DB-3Q for the treatment...

New York, NYPHASE236 participantsDirect Biologics, LLC

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NCT07207200Recruiting

Impact of Morning Light Therapy in IBD

The pilot study will focus on the effects of morning light therapy (MLT) in adult patients with ulcerative colitis (UC) who have evidence of poor sleep quality and active inflammation. The specific po...

New York, NYNA30 participantsIcahn School of Medicine at Mount Sinai

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NCT04263831Recruiting

Low Dose IL-2 for the Treatment of Crohn's Disease

The purpose of this study is to determine the safety and maximum effective dose (MED) of Interleukin-2 in subjects with moderate-to-severe crohn's disease....

New York, NYPHASE130 participantsBoston Children's Hospital

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About Crohns Disease Clinical Trials in New York

Crohn's disease is a chronic inflammatory bowel disease that causes inflammation anywhere in the digestive tract, most commonly in the small intestine and colon. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 23 crohns disease clinical trials recruiting participants in New York, NY. These studies are seeking a combined 5,879 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Sanofi, Weill Medical College of Cornell University and 14 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Crohns Disease Clinical Trials in New York — FAQ

Are there crohns disease clinical trials in New York?

Yes, there are 23 crohns disease clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What crohns disease treatments are being tested?

The 23 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for crohns disease.

Data updated July 16, 2026 from ClinicalTrials.gov