21 Heart Disease Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Heart Disease Studies in New York

NCT07559903Recruiting

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

The primary objective of this protocol is to develop a comprehensive, multicenter international prospective registry to capture long-term clinical outcomes for adult patients undergoing percutaneous c...

New York, NY5,000 participantsEmory University

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NCT03217006Recruiting

Randomization of Single vs Multiple Arterial Grafts

The primary hypothesis of ROMA is that in patients undergoing primary isolated non-emergent coronary artery bypass surgery (CABG), the use of two or more arterial grafts compared to a single arterial ...

New York, NYNA4,300 participantsWeill Medical College of Cornell University

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NCT06590467Recruiting

Abbott Structural Heart Device Registry

The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting. The Registry primarily involves gatherin...

New York, NY2,500 participantsAbbott Medical Devices

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NCT06494501Recruiting

The Prevent Coronary Artery Disease Trial

Despite increasing evidence that exposure to cardiovascular risk factors (CVRF) at an early age increases the prevalence of subclinical atherosclerosis and is associated with a greater risk of cardiov...

New York, NYPHASE31,600 participantsIcahn School of Medicine at Mount Sinai

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NCT06870591Recruiting

Pivotal Study for the Cardiac Performance System (CPS)

This multi-center, observational study evaluates the accuracy of the Cardiac Performance System (CPS), a non-invasive device, for measuring hemodynamic parameters in adult patients undergoing clinical...

New York, NY1,000 participantsSensydia Corporation

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NCT05618353Recruiting

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

Heart disease remains the leading cause of death in Veterans. Inflammation in the arteries of the heart may increase the risk of cardiac death. Patients with heart disease undergoing major surgery are...

New York, NYPHASE4700 participantsVA Office of Research and Development

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NCT07286578Recruiting

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy informed by coronary CT angiography (CCTA) wil...

New York, NYNA700 participantsFundación EPIC

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NCT05677880Recruiting

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

This is an observational study to better understand the risk factors and progression of CADASIL, a leading cause of vascular cognitive impairment and dementia (VCID). 575 participants will be enrolled...

New York, NY660 participantsUniversity of Wisconsin, Madison

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NCT06399705Recruiting

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

This is a research study in minorities to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented wit...

New York, NYPHASE3600 participantsWeill Medical College of Cornell University

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NCT06399692Recruiting

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

This is a research study in women to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a s...

New York, NYPHASE3600 participantsWeill Medical College of Cornell University

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NCT06662500Recruiting

FORWARD CAD IDE Study

The FORWARD CAD IDE Study is a Prospective, Multicenter, Single-Arm, Investigational Device Exemption (IDE) Study conducted to assess the safety and effectiveness of the Shockwave Intravascular Lithot...

New York, NYNA408 participantsShockwave Medical, Inc.

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NCT06932081Recruiting

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital heart disease (ACHD) patients by investigati...

New York, NY400 participantsLeiden University Medical Center

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NCT07296744Recruiting

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

The objective of this study is to assess the safety and efficacy of the Supira System in providing temporary cardiovascular hemodynamic support in patients undergoing HRPCI. Eligible patients will be ...

New York, NYNA358 participantsSupira Medical

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NCT02542683Recruiting

Physical Activity and Cognitive Development in Children

1. Compare physical activity and cognitive functions between children having cardiac surgery with an age-matched group of children undergoing non-cardiac surgery, as well as otherwise healthy siblings...

New York, NY300 participantsColumbia University

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NCT05841784Recruiting

HARP Mindfulness Study

This study was designed using the Multiphase Optimization Strategy (MOST) framework to determine whether two supplemental components increase the efficacy of a mindfulness-based cognitive therapy prog...

New York, NYNA160 participantsNYU Langone Health

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NCT06779630Recruiting

Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

The purpose of the study is to assess the safety and efficacy of the Orsiro® Mission 48- mm Sirolimus-Eluting Coronary Stent System in the treatment of subjects with atherosclerotic lesion(s) \>36 mm ...

New York, NYNA150 participantsTeleflex

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NCT05788666Recruiting

Use of GeriKit to Better Phenotype Older Adults With Ischemic Heart Disease

This study seeks to expand the use of the NYU GeriKit mobile application ("app") in a diverse range of settings to better phenotype older patients, which will enhance both research and patient care....

New York, NYNA150 participantsNYU Langone Health

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NCT07000045Recruiting

Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment

The NODULE-SHOCK trial is a prospective, investigator-initiated, single-center, randomized controlled trial designed to compare the efficacy of intravascular lithotripsy (IVL) with or without rotation...

New York, NYNA120 participantsAnnapoorna Kini

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NCT06796075Recruiting

Identifying Strategies to Reduce Cardiovascular Risk Among Mothers of Young Children

This single-site research study will pilot-test a context-specific cardiovascular disease (CVD) risk prevention program, Mom♥Health, using two childhood centers at Family Health Centers (FHC) at NYU L...

New York, NYNA40 participantsNYU Langone Health

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NCT03891160Recruiting

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clin...

New York, NYNA36 participantsColumbia University

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NCT06931470Recruiting

A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

This study will investigate the acceptability and efficacy of 12 weeks of: Smart-device app-based (MyZone) Asynchronous Virtual, Synchronous Virtual, and in-person aerobic training in individuals at r...

New York, NYNA30 participantsNYU Langone Health

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About Heart Disease Clinical Trials in New York

Heart disease is the leading cause of death worldwide, encompassing conditions that affect the heart and blood vessels. Coronary artery disease, the most common type, occurs when arteries supplying the heart become narrowed or blocked. Risk factors include high blood pressure, high cholesterol, diabetes, and smoking.

There are currently 21 heart disease clinical trials recruiting participants in New York, NY. These studies are seeking a combined 19,812 participants. Research is being sponsored by Emory University, Weill Medical College of Cornell University, Abbott Medical Devices and 12 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Disease Clinical Trials in New York — FAQ

Are there heart disease clinical trials in New York?

Yes, there are 21 heart disease clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What heart disease treatments are being tested?

The 21 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for heart disease.

Data updated July 20, 2026 from ClinicalTrials.gov