11 Alzheimers Disease Clinical Trials in Newport Beach, CA (2026)

Q: How do I join a clinical trial in Newport Beach?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Newport Beach research site will contact you.

Recruiting Alzheimers Disease Studies in Newport Beach

NCT06380751Recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

The primary objective of the study is to measure efficacy of saruparib (AZD5305) plus camizestrant compared with physician's choice CDK4/6i plus ET in patients with BRCA1, BRCA2, or PALB2m, HR-positiv...

Newport Beach, CAPHASE3500 participantsAstraZeneca

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NCT04892173Recruiting

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab ...

Newport Beach, CAPHASE3500 participantsJohnson & Johnson Enterprise Innovation Inc.

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NCT06540833Recruiting

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo in the trea...

Newport Beach, CAPHASE2370 participantsIntra-Cellular Therapies, Inc.

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NCT06651567Recruiting

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

This is a multicenter, randomized, double-blind, placebo-controlled, flexible-dose study of the efficacy, safety, and tolerability of ITI-1284 in patients with agitation associated with Alzheimer's de...

Newport Beach, CAPHASE2320 participantsIntra-Cellular Therapies, Inc.

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NCT06997029Recruiting

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

The purpose of this study is to assess BMS-986500 as monotherapy in advanced solid tumors and as combination therapy in CDK4/6 inhibitor pre-treated advanced breast cancer....

Newport Beach, CAPHASE1234 participantsBristol-Myers Squibb

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NCT05902988Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers....

Newport Beach, CAPHASE1200 participantsVolastra Therapeutics, Inc.

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NCT04142437Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

In this observational study researcher want to learn more about the effectiveness of drug VITRAKVI (generic name: larotrectinib) and how well the drug is tolerated during routine use in patients with ...

Newport Beach, CA150 participantsBayer

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NCT05327010Recruiting

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

This phase II trial tests whether ZEN003694 (ZEN-3694) in combination with talazoparib works to shrink tumors in patients with solid tumors that are unlikely to be cured or controlled with treatment a...

Newport Beach, CAPHASE288 participantsNational Cancer Institute (NCI)

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NCT05635643Recruiting

Study of CHS-114 in Participants With Advanced Solid Tumors

This is a Phase 1, open-label, first-in-human, dose-escalation and expansion study of CHS-114, a monoclonal antibody that targets CCR8, as a monotherapy in patients with solid tumors....

Newport Beach, CAPHASE187 participantsCoherus Oncology, Inc.

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NCT06673017Recruiting

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

This is a multi-center, non-randomized, single-arm, open-label, phase Ib, dose escalation/dose expansion study of PTM-101 when combined with neoadjuvant chemotherapy for the treatment of treatment-naï...

Newport Beach, CAPHASE126 participantsPanTher Therapeutics

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NCT05667649Recruiting

Autologous Activated Adipose-derived Stem Cells (RB-ADSC) Injected Directly Into the Brain for Mild to Moderate Alzheimer's Disease

This is a research study to evaluate the safety of an investigational autologous cell product obtained from participant's own adipose tissue as a possible treatment for Alzheimer disease....

Newport Beach, CAPHASE118 participantsRegeneration Biomedical, Inc.

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About Alzheimers Disease Clinical Trials in Newport Beach

Alzheimer's disease is a progressive brain disorder that destroys memory, thinking skills, and the ability to carry out daily tasks. It is the most common cause of dementia, affecting over 6.7 million Americans age 65 and older. The disease is characterized by amyloid-beta plaques and tau tangles in the brain. Recent FDA approvals of anti-amyloid antibodies like lecanemab (Leqembi) and donanemab have opened a new era of disease-modifying treatments. Clinical trials are now exploring next-generation amyloid-clearing therapies, tau-targeting treatments, anti-inflammatory approaches, and combination strategies. Early-stage patients with mild cognitive impairment or early Alzheimer's are frequently sought for enrollment, and many trials now use blood-based biomarkers for screening.

There are currently 11 alzheimers disease clinical trials recruiting participants in Newport Beach, CA. These studies are seeking a combined 2,493 participants. Research is being sponsored by AstraZeneca, Johnson & Johnson Enterprise Innovation Inc., Intra-Cellular Therapies, Inc. and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Alzheimers Disease Clinical Trials in Newport Beach — FAQ

Are there alzheimers disease clinical trials in Newport Beach?

Yes, there are 11 alzheimers disease clinical trials currently recruiting in Newport Beach, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Newport Beach?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Newport Beach research site will contact you about next steps.

Are clinical trials in Newport Beach free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Newport Beach studies also compensate for your time and travel.

What alzheimers disease treatments are being tested?

The 11 active trials in Newport Beach are testing new therapies including novel drugs, biologics, and treatment approaches for alzheimers disease.

Data updated July 17, 2026 from ClinicalTrials.gov