Newport Beach, CA8 Active Studies

Rheumatoid Arthritis Clinical Trials in Newport Beach, CA

Find 8 actively recruiting rheumatoid arthritis clinical trials in Newport Beach, CA. Connect with local research sites and explore new treatment options.

8
Active Trials
6
Sponsors
4,698
Enrolling

Recruiting Rheumatoid Arthritis Studies in Newport Beach

RecruitingNewport Beach, CANCT05624450

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

The purpose of this study is to evaluate the effect of tozorakimab, as an add-on to SoC in patients with viral lung infection requiring supplemental oxygen, on the prevention of death or progression t...

2,870 participants
AstraZeneca
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RecruitingNewport Beach, CANCT06109779

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

A global study to assess the efficacy and tolerability of rilvegostomig compared to placebo in combination with investigator's choice of chemotherapy in participants with BTC after surgical resection ...

750 participants
AstraZeneca
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RecruitingNewport Beach, CANCT06880744

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will evaluate how safe and ef...

530 participants
AbbVie
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RecruitingNewport Beach, CANCT06722157

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan...

180 participants
Boehringer Ingelheim
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RecruitingNewport Beach, CANCT05769153

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)

The primary purpose of this study is to evaluate the safety and durability of single- and repeat administration of AR-14034 Sustained Release (SR) in subjects with neovascular age-related macular dege...

140 participants
Alcon Research
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RecruitingNewport Beach, CANCT06769048

A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

This study is open to adults aged 50 years and older with geographic atrophy that was diagnosed by imaging of the retina. The purpose of this study is to find out whether a medicine called BI 1584862 ...

138 participants
Boehringer Ingelheim
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RecruitingNewport Beach, CANCT06095128

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim...

65 participants
Takeda
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RecruitingNewport Beach, CANCT05709314

A Study of AMDX-2011P in Participants With CAA

The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P in participants with cerebral amyloid angiopathy (...

25 participants
Amydis Inc.
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About Rheumatoid Arthritis Clinical Trials in Newport Beach

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 8 rheumatoid arthritis clinical trials recruiting participants in Newport Beach, CA. These studies are seeking a combined 4,698 participants. Research is being sponsored by AstraZeneca, AbbVie, Boehringer Ingelheim and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Newport Beach — FAQ

Are there rheumatoid arthritis clinical trials in Newport Beach?

Yes, there are 8 rheumatoid arthritis clinical trials currently recruiting in Newport Beach, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Newport Beach?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Newport Beach research site will contact you about next steps.

Are clinical trials in Newport Beach free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Newport Beach studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 8 active trials in Newport Beach are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov