Orange, CALIFORNIA7 Active Studies

Epilepsy Clinical Trials in Orange, CALIFORNIA

Find 7 actively recruiting epilepsy clinical trials in Orange, CALIFORNIA. Connect with local research sites and explore new treatment options.

7
Active Trials
3
Sponsors
1,218
Enrolling

Recruiting Epilepsy Studies in Orange

RecruitingOrange, CALIFORNIANCT05716100

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

The X-TOLE3 Phase 3 clinical trial is a randomized, double-blind, placebo-controlled study that will evaluate the clinical efficacy, safety and tolerability of XEN1101 administered as adjunctive thera...

360 participants
Xenon Pharmaceuticals Inc.
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RecruitingOrange, CALIFORNIANCT05077904

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no re...

350 participants
UCB Biopharma SRL
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RecruitingOrange, CALIFORNIANCT05667142

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of XEN1101 administered as adjunctive treatment in primar...

160 participants
Xenon Pharmaceuticals Inc.
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RecruitingOrange, CALIFORNIANCT04666610

A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

The purpose of the study is to test the efficacy, safety and tolerability of brivaracetam monotherapy in study participants 2 to 25 years of age inclusive with childhood absence epilepsy (CAE) or juve...

160 participants
UCB Biopharma SRL
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RecruitingOrange, CALIFORNIANCT06315322

A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

The purpose of the study is to investigate the long-term safety and tolerability of brivaracetam in study participants with childhood absence epilepsy or juvenile absence epilepsy....

120 participants
UCB Biopharma SRL
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RecruitingOrange, CALIFORNIANCT05135091

FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

This clinical trial is designed to test whether a single image-guided intracerebral administration of inhibitory nerve cells, called interneurons (NRTX-1001), into subjects with drug-resistant unilate...

58 participants
Neurona Therapeutics
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RecruitingOrange, CALIFORNIANCT06422923

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

This is a multicenter, single arm, open label clinical trial that is designed to test the safety and preliminary efficacy of single administration inhibitory nerve cells called interneurons (NRTX-1001...

10 participants
Neurona Therapeutics
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About Epilepsy Clinical Trials in Orange

Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. It affects about 50 million people worldwide. Treatment includes antiseizure medications, surgery, and neurostimulation devices.

There are currently 7 epilepsy clinical trials recruiting participants in Orange, CALIFORNIA. These studies are seeking a combined 1,218 participants. Research is being sponsored by Xenon Pharmaceuticals Inc., UCB Biopharma SRL, Neurona Therapeutics. Clinical trial participation is free and participants receive study-related medical care at no cost.

Epilepsy Clinical Trials in Orange — FAQ

Are there epilepsy clinical trials in Orange?

Yes, there are 7 epilepsy clinical trials currently recruiting in Orange, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What epilepsy treatments are being tested?

The 7 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for epilepsy.

Data updated March 2, 2026 from ClinicalTrials.gov