Orlando, FLORIDA8 Active Studies

Crohns Disease Clinical Trials in Orlando, FLORIDA

Find 8 actively recruiting crohns disease clinical trials in Orlando, FLORIDA. Connect with local research sites and explore new treatment options.

8
Active Trials
6
Sponsors
2,003
Enrolling

Recruiting Crohns Disease Studies in Orlando

RecruitingOrlando, FLORIDANCT06819891

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately...

425 participants
Hoffmann-La Roche
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RecruitingOrlando, FLORIDANCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from the anus, and belly pain. The main aim of this stud...

400 participants
Takeda
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RecruitingOrlando, FLORIDANCT06227910

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

396 participants
Takeda
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RecruitingOrlando, FLORIDANCT06937099

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizumab and concomitantly administered tirzepatide in adult participants with moderat...

290 participants
Eli Lilly and Company
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RecruitingOrlando, FLORIDANCT06450197

Phase IIa Study Evaluating AZD7798 in Crohn's Disease

This is a randomised, double-blind, parallel group, placebo-controlled Phase IIa study designed to evaluate the efficacy and safety of AZD7798 in participants with moderate to severe Crohn's disease....

192 participants
AstraZeneca
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RecruitingOrlando, FLORIDANCT05995353

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This study will assess the pharmacokinetics, ...

110 participants
AbbVie
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RecruitingOrlando, FLORIDANCT06045754

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together with ustekinumab (UST) in adults with mode...

100 participants
Takeda
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RecruitingOrlando, FLORIDANCT07113522

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

This is a Phase 2, multicenter, platform study in adult participants with IBD (moderately to severely active Crohn's Disease or Ulcerative Colitis). The primary goal of this study is to assess the saf...

90 participants
Mirador Therapeutics, Inc.
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About Crohns Disease Clinical Trials in Orlando

Crohn's disease is a chronic inflammatory bowel disease that causes inflammation anywhere in the digestive tract, most commonly in the small intestine and colon. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 8 crohns disease clinical trials recruiting participants in Orlando, FLORIDA. These studies are seeking a combined 2,003 participants. Research is being sponsored by Hoffmann-La Roche, Takeda, Eli Lilly and Company and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Crohns Disease Clinical Trials in Orlando — FAQ

Are there crohns disease clinical trials in Orlando?

Yes, there are 8 crohns disease clinical trials currently recruiting in Orlando, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What crohns disease treatments are being tested?

The 8 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for crohns disease.

Data updated March 2, 2026 from ClinicalTrials.gov