Orlando, FLORIDA9 Active Studies

Small Cell Lung Cancer Clinical Trials in Orlando, FLORIDA

Find 9 actively recruiting small cell lung cancer clinical trials in Orlando, FLORIDA. Connect with local research sites and explore new treatment options.

9
Active Trials
8
Sponsors
3,793
Enrolling

Recruiting Small Cell Lung Cancer Studies in Orlando

RecruitingOrlando, FLORIDANCT06077760

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

The goal of this study is to evaluate intismeran autogene plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of margin negative, completely resected Stage II, IIIA, IIIB (...

868 participants
Merck Sharp & Dohme LLC
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RecruitingOrlando, FLORIDANCT06635824

Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)

This is a multicenter, randomized, open-label, international, Phase 3 trial to evaluate the efficacy and safety of acasunlimab in combination with pembrolizumab versus docetaxel (standard of care) in ...

702 participants
Genmab
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RecruitingOrlando, FLORIDANCT05671510

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

The goal of this Phase 3 clinical trial is study the safety and efficacy of the nextgen anti-CTLA-4 antibody, gotistobart (ONC-392/BNT316), in patients with metastatic non-small cell lung cancer who h...

600 participants
OncoC4, Inc.
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RecruitingOrlando, FLORIDANCT06203210

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

This study was designed to compare the efficacy and safety of I-DXd with treatment of physician's choice in participants with relapsed small cell lung cancer (SCLC)....

540 participants
Daiichi Sankyo
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RecruitingOrlando, FLORIDANCT05498428

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

The purpose of this study is to assess the anti-tumor activity and safety of amivantamab which will be administered as a co-formulation with recombinant human hyaluronidase PH20 (rHuPH20) (subcutaneou...

390 participants
Janssen Research & Development, LLC
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RecruitingOrlando, FLORIDANCT06745323

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC

The primary objective of this study is to describe the antitumor activity of tarlatamab in participants with small cell lung cancer (SCLC)....

240 participants
Amgen
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RecruitingOrlando, FLORIDANCT05142696

A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

This study aims to establish a safe and well tolerated dose of \[177Lu\]Lu-DOTA-TATE in combination with carboplatin, etoposide and atezolizumab in this setting and to assess preliminary efficacy of t...

200 participants
Novartis Pharmaceuticals
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RecruitingOrlando, FLORIDANCT06667908

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

The purpose of this study is to determine whether JNJ-90301900 added to concurrent platinum-based doublet chemotherapy with radiation therapy (cCRT) followed by consolidation immunotherapy (cIT) can i...

130 participants
Johnson & Johnson Enterprise Innovation Inc.
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RecruitingOrlando, FLORIDANCT06362252

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

This study is designed to evaluate the safety and efficacy of ifinatamab deruxtecan (I-DXd) in combination with immune checkpoint inhibitor (ICI) atezolizumab with or without carboplatin in participan...

123 participants
Daiichi Sankyo
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About Small Cell Lung Cancer Clinical Trials in Orlando

Small cell lung cancer (SCLC) is an aggressive form of lung cancer that tends to grow and spread faster than non-small cell lung cancer. It is strongly associated with smoking. Treatment typically involves chemotherapy combined with immunotherapy and radiation.

There are currently 9 small cell lung cancer clinical trials recruiting participants in Orlando, FLORIDA. These studies are seeking a combined 3,793 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Genmab, OncoC4, Inc. and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Small Cell Lung Cancer Clinical Trials in Orlando — FAQ

Are there small cell lung cancer clinical trials in Orlando?

Yes, there are 9 small cell lung cancer clinical trials currently recruiting in Orlando, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What small cell lung cancer treatments are being tested?

The 9 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for small cell lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov