47 Erectile Dysfunction Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Erectile Dysfunction Studies in Philadelphia

NCT06016946Recruiting

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

This project is a global, multicenter, prospective, longitudinal, observational natural history study that can be used to understand the disease progression and support the development of safe and eff...

Philadelphia, PA3,000 participantsFriedreich's Ataxia Research Alliance

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NCT06525064Recruiting

Health-E You Efficacy Trial for Male Adolescents

This study will involve evaluating Health-E You/Salud ìTu™, a web-based, pre-visit mobile app designed to support adolescent male youth and his clinicians in discussing sexual and reproductive health ...

Philadelphia, PANA2,752 participantsJohns Hopkins University

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NCT06986148Recruiting

Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring ...

Philadelphia, PANA2,000 participantsAnn & Robert H Lurie Children's Hospital of Chicago

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NCT06377033Recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Given the expansion of indications for genetic testing and our understanding of conditions for which the results change medical management, it is imperative to consider novel ways to deliver care beyo...

Philadelphia, PANA1,000 participantsUniversity of Pennsylvania

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NCT07209254Recruiting

Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension

A multicenter randomized trial that will compare the effectiveness of two postpartum blood pressure (BP) management strategies in improving blood pressure and cardiac function and increasing patient e...

Philadelphia, PANA770 participantsJennifer Lewey, MD, MPH

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NCT06994442Recruiting

Optimizing Pain Treatment in Children On Mechanical Ventilation

In this clinical trial, investigators want to learn more about using non-opioid pain medications for children with acute respiratory failure. Right now, doctors give these children opioids to help wit...

Philadelphia, PAPHASE3644 participantsWeill Medical College of Cornell University

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NCT05156983Recruiting

A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery

The aim of this study is to find out the effects of TAK-330 compared with four-factor prothrombin complex concentrate (4F-PCC) as part of standard treatment other than Prothromplex Total for anticoagu...

Philadelphia, PAPHASE3440 participantsTakeda

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NCT05499507Recruiting

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

The overarching goal of our proposal is to reduce disparities in perinatal cardiovascular disease risk factors among Black women utilizing a community-driven, social ecological framework....

Philadelphia, PANA432 participantsTemple University

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NCT00360646Recruiting

Drug-Induced Liver Injury (DILI) Network Retrospective

The purpose of this study is to establish retrospectively a nationwide registry of patients who have suffered drug-induced liver injury (DILI), and to collect, immortalize, and store serum, DNA, and l...

Philadelphia, PA400 participantsDuke University

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NCT06736704Recruiting

SNV4818 in Participants With Advanced Solid Tumors

This study is testing a new medicine, SNV4818, for people with advanced cancers. The researchers want to find out if SNV4818 is safe, well-tolerated, and effective in treating solid tumors. They are i...

Philadelphia, PAPHASE1320 participantsPikavation Therapeutics, Inc.

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NCT06541002Recruiting

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

This research study is evaluating the efficacy of a novel self-administered digital application for improving sexual health outcomes, quality of life, and psychological distress in hematopoietic stem ...

Philadelphia, PANA300 participantsMassachusetts General Hospital

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NCT06670001Recruiting

MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

This is a three-arm, randomized, controlled trial to test the effectiveness of gamification plus a social incentive - either social support or competition - to increase adherence to physical activity ...

Philadelphia, PANA270 participantsUniversity of Pennsylvania

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NCT06953583Recruiting

A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old

In this study, researchers will learn more about the effects and safety of BIIB141, also known as omaveloxolone or SKYCLARYS®. This drug has been approved, or made available for doctors to prescribe, ...

Philadelphia, PAPHASE3255 participantsBiogen

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NCT07205718Recruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

TAK-188 is a new medicine that targets a protein called CCR8, which is found on the surface of certain cells (Tregs) inside tumors. These cells can weaken the body's ability to fight cancer. TAK-188 m...

Philadelphia, PAPHASE1223 participantsTakeda

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NCT06795412Recruiting

Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

The primary objective of this study is to determine the recommended Phase 2 doses (RP2D(s)) and maximum tolerated dose (MTD) of PYX-201 in combination with pembrolizumab for participants with advanced...

Philadelphia, PAPHASE1220 participantsPyxis Oncology, Inc

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NCT05675865Recruiting

Cryoablation for Monomorphic Ventricular Tachycardia

The objective of this clinical study is to evaluate the safety and effectiveness of the Adagio VT Cryoablation System in the ablation treatment of Sustained Monomorphic Ventricular Tachycardia (SMVT)...

Philadelphia, PANA206 participantsAdagio Medical

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NCT06125743Recruiting

Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]

The goal of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) to improve LEF self-management and reduce LEF-associated symptom bur...

Philadelphia, PANA204 participantsAbramson Cancer Center at Penn Medicine

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NCT06539741Recruiting

Variability in Analgesic Response to Ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain. However, there is variability in analgesic response, and some pati...

Philadelphia, PA200 participantsUniversity of Pennsylvania

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NCT06108050Recruiting

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

This Phase 1 first-in-human study will investigate the safety, tolerability, pharmacokinetics (PK), immunogenicity, and preliminary antitumor activity of JZP898 monotherapy as well as JZP898 in combin...

Philadelphia, PAPHASE1177 participantsJazz Pharmaceuticals

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NCT04752826Recruiting

BI-1808 As a Single Agent and with Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

The goal of this first in human clinical trial is to test BI-1808 administered as single agent and in combination with pembrolizumab in subjects with advanced malignancies whose disease has progressed...

Philadelphia, PAPHASE1176 participantsBioInvent International AB

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NCT07072364Recruiting

Videos to Aid Decision Making for Fibroid Treatment

Uterine fibroids are a common condition that can cause heavy and/or painful menstrual bleeding. There are many treatment options, but they vary in efficacy, side effects, short-term recovery and long-...

Philadelphia, PANA154 participantsUniversity of Pennsylvania

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NCT06055439Recruiting

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

The goal of this clinical trial is to evaluate CHM-2101, an autologous CDH17 CAR T-cell therapy for the treatment of advanced gastrointestinal (GI) cancers that are relapsed or refractory to at least ...

Philadelphia, PAPHASE1135 participantsChimeric Therapeutics

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NCT06395519Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

This is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and anti- tumor acti...

Philadelphia, PAPHASE1120 participants858 Therapeutics, Inc.

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NCT07213817Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

This study aims to find the right dosage and evaluate the safety and effectiveness of the drug IPN60300 in adults with advanced solid tumours, which are cancers that have spread to other parts of the ...

Philadelphia, PAPHASE1114 participantsIpsen

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NCT05878860Recruiting

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

This study will evaluate the safety and tolerability of ATSN-201 in male subjects ≥ 6 years of age with RS1-associated X-linked retinoschisis (XLRS)....

Philadelphia, PAPHASE397 participantsAtsena Therapeutics Inc.

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NCT07282587Recruiting

Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

This is a two-stage Phase 2 trial evaluating the efficacy and safety of ONC206 in participants with Pheochromocytoma and Paraganglioma (PCPG)....

Philadelphia, PAPHASE290 participantsJazz Pharmaceuticals

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NCT06447025Recruiting

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

An open label study designed to evaluate the safety, PK, PD, and clinical effects of long-term daily administration of CTI-1601 enrolling adolescent and adult patients with FRDA who have participated ...

Philadelphia, PAPHASE285 participantsLarimar Therapeutics, Inc.

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NCT05932680Recruiting

Limited-duration Teclistamab

This is a single-arm, non-inferiority study in which patients who have achieved a very good partial response (VGPR) or better, according to International Myeloma Working Group (IMWG) response criteria...

Philadelphia, PAPHASE275 participantsAbramson Cancer Center at Penn Medicine

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NCT06829953Recruiting

Get ActivE Study for At-risk Youth

The study will adapt and deploy a digital Behavioral Activation app with mobile sensing, supported by health coaches, that encourages youth to engage in positive activities. The study has the potentia...

Philadelphia, PANA75 participantsUniversity of Pittsburgh

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NCT06352359Recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

This is a Phase I/II open label study of intravenous (IV) infusion of ONC-841 as a single agent or in combination in patients with advanced/metastatic solid tumors. The study will evaluate seven dose ...

Philadelphia, PAPHASE172 participantsOncoC4, Inc.

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NCT05329103Recruiting

A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors

This is a first-in-human, dose escalation, repeat-dose, multi-center, open-label study evaluating safety, tolerability, PK, and preliminary antitumor activity of PEEL-224 in patients with advanced sol...

Philadelphia, PAPHASE165 participantsPeel Therapeutics Inc

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NCT05626114Recruiting

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

This study will evaluate the success and safety of subretinal surgical delivery as well as the preliminary activity of OpRegen in participants with geographic atrophy (GA) secondary to age-related mac...

Philadelphia, PAPHASE260 participantsGenentech, Inc.

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NCT05138575Recruiting

SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

This study will test whether pharmacologic agents that may improve mitochondrial function and energy fuel metabolism \[Empagliflozin (Empa)\], with and without additional supplements that increase per...

Philadelphia, PAPHASE253 participantsUniversity of Pennsylvania

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NCT04913805Recruiting

Matching Perfusion and Metabolic Activity in HFpEF

This study will test whether pharmacologic agents that increase perfusion \[Potassium Nitrate (KNO3)\], with and without additional supplements that may improve mitochondrial function \[Propionyl-L-Ca...

Philadelphia, PAPHASE253 participantsUniversity of Pennsylvania

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NCT06581146Recruiting

A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition

XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition. It is caused by changes in the MTM1 gene which stops or slows down normal muscle development, causing severe muscle weakness...

Philadelphia, PA50 participantsAstellas Gene Therapies

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NCT06959706Recruiting

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

The primary objectives of this study are to evaluate the safety and tolerability of TGW101 and determine the recommended dosing regimen(s) for further study. The secondary objectives are to assess pha...

Philadelphia, PAPHASE150 participantsTagworks Pharmaceuticals BV

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NCT06402201Recruiting

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

CDR404 is a highly potent and specific T-cell engaging bispecific and bivalent antibody designed for the treatment of cancers positive for the tumor-associated antigen melanoma-associated antigen 4 (M...

Philadelphia, PAPHASE142 participantsCDR-Life AG

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NCT05705024Recruiting

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of...

Philadelphia, PAPHASE238 participantsUniversity of Illinois at Chicago

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NCT02637934Recruiting

Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

Up to 40 evaluable women with known or suspected epithelial ovarian, fallopian tube, or primary peritoneal cancer will participate in two different imaging cohorts. The Biodistribution cohort will inc...

Philadelphia, PAPHASE135 participantsAbramson Cancer Center at Penn Medicine

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NCT07167446Recruiting

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

This is a pilot, prospective, randomized study evaluating the feasibility and acceptability of incorporating hemp-derived cannabidiol (CBD) supplementation to prevent oxaliplatin-induced peripheral ne...

Philadelphia, PAEARLY_PHASE130 participantsFox Chase Cancer Center

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NCT06817863Recruiting

A Self-Guided Mobile Intervention for Adults With Binge Eating and Obesity

The proposed study is an open label, non randomized, waitlist controlled single group feasibility study of the feasibility and usability of a digital intervention (called ChangeBite) to be used by ind...

Philadelphia, PAPHASE130 participantsDrexel University

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NCT04796012Recruiting

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

This trial is a multi-center, non-randomized, open-label Phase I/II study evaluating the feasibility and efficacy of vincristine, irinotecan, temozolomide, and atezolizumab in children with relapsed/r...

Philadelphia, PAPHASE123 participantsUniversity of Texas Southwestern Medical Center

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NCT04889716Recruiting

CAR-T Followed by Bispecific Antibodies

The research study is being conducted to test the safety and effectiveness of the experimental drug mosunetuzumab (Cohort 1) or obinutuzumab and glofitamab (Cohort 2) when given after CAR (genetically...

Philadelphia, PAPHASE223 participantsAbramson Cancer Center at Penn Medicine

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NCT06376162Recruiting

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or...

Philadelphia, PAPHASE120 participantsPedAL BCU, LLC

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Philadelphia, PAPHASE120 participantsAdaptimmune

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NCT07180355Recruiting

A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

This is a phase 1b, first in-human, open-label, dose-finding study investigating the safety and tolerability of SGT-212 in participants with Friedreich's ataxia (FA). It will be delivered via dual int...

Philadelphia, PAPHASE110 participantsSolid Biosciences Inc.

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NCT07218887Recruiting

ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy

This Phase 1/2 study is an open-label, dose finding and dose expansion study investigating the safety, tolerability, and efficacy of a single IV infusion of ALXN2350 in adult participants with BAG3 as...

Philadelphia, PAPHASE16 participantsAlexion Pharmaceuticals, Inc.

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About Erectile Dysfunction Clinical Trials in Philadelphia

Erectile dysfunction is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It affects about 30 million men in the U.S. and is often a sign of underlying cardiovascular disease. Treatment includes PDE5 inhibitors, vacuum devices, and penile implants.

There are currently 47 erectile dysfunction clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 15,614 participants. Research is being sponsored by Friedreich's Ataxia Research Alliance, Johns Hopkins University, Ann & Robert H Lurie Children's Hospital of Chicago and 34 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Erectile Dysfunction Clinical Trials in Philadelphia — FAQ

Are there erectile dysfunction clinical trials in Philadelphia?

Yes, there are 47 erectile dysfunction clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What erectile dysfunction treatments are being tested?

The 47 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for erectile dysfunction.

Data updated July 18, 2026 from ClinicalTrials.gov