Philadelphia, PA8 Active Studies

Geographic Atrophy Clinical Trials in Philadelphia, PA

Find 8 actively recruiting geographic atrophy clinical trials in Philadelphia, PA. Connect with local research sites and explore new treatment options.

8
Active Trials
7
Sponsors
633
Enrolling

Recruiting Geographic Atrophy Studies in Philadelphia

RecruitingPhiladelphia, PANCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingPhiladelphia, PANCT06930625

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

The primary purpose of this study is to assess the effect of Debio 4126 in the maintenance of the levels of insulin-like growth factor 1 (IGF-1) ≤1x upper limit of normal (ULN) in the double-blind per...

119 participants
Debiopharm International SA
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RecruitingPhiladelphia, PANCT04468061

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts ...

110 participants
Dana-Farber Cancer Institute
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RecruitingPhiladelphia, PANCT05957367

A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies

This is a Phase 1/2, multicenter, open-label (unless otherwise specified in a combination-specific module) study of inlexisertib in combination with anticancer therapies. Modules within the master pro...

94 participants
Deciphera Pharmaceuticals, LLC
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RecruitingPhiladelphia, PANCT06388083

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease

The goal of this clinical trial is to evaluate the safety, tolerability, and efficacy of tinlarebant in subjects with Stargardt Disease...

60 participants
Belite Bio, Inc
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RecruitingPhiladelphia, PANCT06208748

SARC044: a Phase II Trial of Bezuclastinib in Combination with Sunitinib in Patients with GIST

This is an open label, single arm, phase 2 trial investigating bezuclastinib plus sunitinib in patients with GIST who have previously progressed on sunitinib....

40 participants
Sarcoma Alliance for Research through Collaboration
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RecruitingPhiladelphia, PANCT04434040

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

The purpose of this study is to determine if a combination of two drugs sacituzumab govitecan and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulatin...

40 participants
Dana-Farber Cancer Institute
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RecruitingPhiladelphia, PANCT03266640

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovi...

20 participants
New York Medical College
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About Geographic Atrophy Clinical Trials in Philadelphia

Geographic atrophy is the advanced form of dry age-related macular degeneration, involving progressive loss of retinal cells. It leads to enlarging blind spots in central vision. Recently approved complement inhibitor therapies can slow progression.

There are currently 8 geographic atrophy clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 633 participants. Research is being sponsored by Laura Huppert, MD, BA, Debiopharm International SA, Dana-Farber Cancer Institute and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Geographic Atrophy Clinical Trials in Philadelphia — FAQ

Are there geographic atrophy clinical trials in Philadelphia?

Yes, there are 8 geographic atrophy clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What geographic atrophy treatments are being tested?

The 8 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for geographic atrophy.

Data updated March 2, 2026 from ClinicalTrials.gov