28 Ankylosing Spondylitis Clinical Trials in Pittsburgh, PA (2026)

Q: How do I join a clinical trial in Pittsburgh?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you.

Recruiting Ankylosing Spondylitis Studies in Pittsburgh

NCT06272045Recruiting

Early Intervention to Promote Cardiovascular Health of Mothers and Children

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) is a cluster randomized clinical trial, funded by the National Heart Lung \& Blood Institute. The study is designed...

Pittsburgh, PANA6,618 participantsJHSPH Center for Clinical Trials

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NCT03228290Recruiting

Functional Assessment in Liver Transplantation

This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at ba...

Pittsburgh, PA5,000 participantsUniversity of California, San Francisco

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NCT03759717Recruiting

Molecular and Cellular Characterization of Skull Base Tumors

The purpose of the study is to analyze biological samples and genetic material for basic science research investigating the molecular and cellular characterization of skull base tumors....

Pittsburgh, PA4,000 participantsUniversity of Pittsburgh

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NCT02890342Recruiting

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Background: People s bodies need to break down food into the chemicals. These chemicals are used for energy and growth. Some people cannot process all chemicals very well. Too much of some chemicals ...

Pittsburgh, PA1,045 participantsNational Human Genome Research Institute (NHGRI)

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NCT06512064Recruiting

Acoustic Waveform Respiratory Evaluation

The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify di...

Pittsburgh, PANA800 participantsIndiana University

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NCT00869817Recruiting

Dominantly Inherited Alzheimer Network (DIAN)

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation....

Pittsburgh, PA700 participantsWashington University School of Medicine

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NCT06863272Recruiting

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

The purpose of this substudy is to assess the efficacy and safety of ifinatamab deruxtecan (I-DXd), given alone or with other treatments in participants with metastatic castration-resistant prostate c...

Pittsburgh, PAPHASE1360 participantsMerck Sharp & Dohme LLC

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NCT07261423Recruiting

Pollution Intervention to Impact Kids Asthma Study

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with as...

Pittsburgh, PANA351 participantsUniversity of Pittsburgh

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NCT07335497Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) ...

Pittsburgh, PAPHASE1290 participantsCrescent Biopharma, Inc.

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NCT07141706Recruiting

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

This is a multicenter, open-label, multiple-dose, FIH Phase 1a/1b study. Phase 1a adopts an accelerated titration design and a BOIN design to identify the MTD or MAD of DB-1317; Phase 1b includes up t...

Pittsburgh, PAPHASE1233 participantsDualityBio Inc.

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NCT05288803Recruiting

Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories

This study will examine the impact of a new clinical decision support tool for rehabilitation after total knee arthroplasty (TKA). Typically, TKA rehabilitation is generic with most patients receiving...

Pittsburgh, PA200 participantsVA Office of Research and Development

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NCT06833853Recruiting

A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients

The purpose of this research is to learn if the CellSearch Circulating Tumor Cells (CTC) test can help doctors in making decisions about treatment and monitoring of breast cancer. The test consists of...

Pittsburgh, PA187 participantsMenarini Silicon Biosystems, INC

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NCT06022029Recruiting

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expan...

Pittsburgh, PAPHASE1168 participantsOncoNano Medicine, Inc.

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NCT03056794Recruiting

Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies

Children and adults with pyruvate dehydrogenase complex deficiency (PDCD) are participating in a research study seeking to better understand the genetic causes, symptoms, usefulness of current treatme...

Pittsburgh, PA150 participantsUniversity of Pittsburgh

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NCT07322406Recruiting

Kaempferol Absorption and Pharmacokinetics Evaluation

This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the...

Pittsburgh, PANA120 participantsUniversity of Pittsburgh

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NCT07069712Recruiting

A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

GEMINI-PeriOp GC study will assess the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity of novel agents or novel combinations as perioperative treatment in participants ...

Pittsburgh, PAPHASE2100 participantsAstraZeneca

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NCT06422871Recruiting

PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

The goal of this observational study is to increase the understanding of the safety and performance of Merit Medical's HeRO Graft System (HeRO) and Super HeRO Adaptor and Support Seal System (Super He...

Pittsburgh, PA100 participantsMerit Medical Systems, Inc.

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NCT07423078Recruiting

Window of Opportunity in Preserving Laryngeal Function Trial

This trial will study the safety and tolerability and disease survival rates in adult patients with recurrent/metastatic (R/M) HNSCC when treated with carboplatin or cisplatin, paclitaxel, and toripal...

Pittsburgh, PAPHASE287 participantsMatthew Spector

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NCT07115004Recruiting

Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

This is a phase 3 study that will evaluate subcutaneous (SC) VGA039 in patients with von Willebrand Disease (VWD)...

Pittsburgh, PAPHASE360 participantsVega Therapeutics, Inc

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NCT07124078Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

This study will be conducted to compare Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy....

Pittsburgh, PAPHASE260 participantsIncyte Corporation

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NCT07123155Recruiting

Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and exploratory clinical efficacy of S-606001 in adult participants with LOPD as an add-on to ERT....

Pittsburgh, PAPHASE245 participantsShionogi

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NCT07493512Recruiting

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

The primary objective of this trial is to determine the safety profile of xaluritamig at the proposed regimen in adult participants with metastatic castration-resistant prostate cancer (mCRPC)....

Pittsburgh, PAPHASE140 participantsAmgen

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NCT06654037Recruiting

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

This phase I trial tests the safety, side effects, and best dose of abemaciclib in combination with 5-fluorouracil and how well it works in treating patients with colorectal cancer that has spread fro...

Pittsburgh, PAPHASE139 participantsNational Cancer Institute (NCI)

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NCT05653440Recruiting

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of ...

Pittsburgh, PAPHASE230 participantsUniversity of Pittsburgh

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NCT04925492Recruiting

PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD

The purpose of this study is to find objective biomarkers of vaso-occlusion (blood vessel blockage) in people with SCD. Using information from earlier studies and work being done, researchers have dev...

Pittsburgh, PAPHASE120 participantsEnrico Novelli

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NCT07439887Recruiting

Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease

A Phase 1/2, open-label, non-randomized, dose-escalation study, where a minimum of 9 and a maximum of 18 eligible patients with Stargardt Disease will be enrolled sequentially in up to 3 dose cohorts ...

Pittsburgh, PAPHASE118 participantsRay Therapeutics, Inc.

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NCT06052839Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

The rationale for the new sequence of pulsed dose chemotherapy proposed in this trial is based on the hypotheses that current standard dosing of chemotherapy plus pembrolizumab ultimately suppresses t...

Pittsburgh, PAPHASE215 participantsDan Zandberg

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NCT07282847Recruiting

A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late Onset Pompe Disease (PROGRESS-GT LOPD)

This is a single-arm, open-label, dose-escalation study to evaluate the safety, tolerability and efficacy of a single intravenous infusion of AB-1009 in adult participants with late-onset Pompe diseas...

Pittsburgh, PAPHASE112 participantsAskBio Inc

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About Ankylosing Spondylitis Clinical Trials in Pittsburgh

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 28 ankylosing spondylitis clinical trials recruiting participants in Pittsburgh, PA. These studies are seeking a combined 20,848 participants. Research is being sponsored by JHSPH Center for Clinical Trials, University of California, San Francisco, University of Pittsburgh and 21 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Pittsburgh — FAQ

Are there ankylosing spondylitis clinical trials in Pittsburgh?

Yes, there are 28 ankylosing spondylitis clinical trials currently recruiting in Pittsburgh, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Pittsburgh?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you about next steps.

Are clinical trials in Pittsburgh free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Pittsburgh studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 28 active trials in Pittsburgh are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated July 17, 2026 from ClinicalTrials.gov