11 Multiple Sclerosis Clinical Trials in Pittsburgh, PA (2026)

Q: How do I join a clinical trial in Pittsburgh?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you.

Recruiting Multiple Sclerosis Studies in Pittsburgh

NCT02994121Recruiting

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treat...

Pittsburgh, PA7,500 participantsUniversity of Pittsburgh

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NCT01353547Recruiting

Genes and Environment in Multiple Sclerosis

The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease cause...

Pittsburgh, PA5,000 participantsColumbia University

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NCT02701244Recruiting

A Registry Study of Breast Microseed Treatment

For women diagnosed with early stage breast cancer, lumpectomy followed by radiation is a common treatment option. Radiation treatment is typically delivered to the whole breast, five times per week, ...

Pittsburgh, PA420 participantsConcure Oncology-Breast Microseed Inc.

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NCT06351631Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bome...

Pittsburgh, PAPHASE3400 participantsMerck Sharp & Dohme LLC

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NCT04429087Recruiting

A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

This study is open to adults with small cell lung cancer and other neuroendocrine cancers that are positive for the tumour marker delta-like 3 (DLL3). The study is in people with advanced cancer for w...

Pittsburgh, PAPHASE1300 participantsBoehringer Ingelheim

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NCT03391778Recruiting

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion....

Pittsburgh, PAPHASE1250 participantsUSWM CT, LLC

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NCT06311578Recruiting

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

The purpose of this study is to determine the safety, feasibility, recommended dose(s) and regimen(s) of JNJ-87704916 as monotherapy and in combination with cetrelimab....

Pittsburgh, PAPHASE1126 participantsJohnson & Johnson Enterprise Innovation Inc.

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NCT05219955Recruiting

Caregiver Stress and Sleep Study

The purpose of this research study is to better understand how stress, sleep and activity might impact caregivers' mood and brain health. This study includes a randomized experimental component where ...

Pittsburgh, PANA120 participantsUniversity of Pittsburgh

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NCT04369560Recruiting

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

This is a phase Ib study of the safety and performance of a novel intravesical contrast-enhanced Magnetic Resonance Imaging protocol for determination of bladder cancer stage prior to transurethral re...

Pittsburgh, PAEARLY_PHASE142 participantsJodi Maranchie

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NCT07001592Recruiting

Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors

This research study aims to evaluate the safety and determine the optimal dose of a new experimental drug, vvDD-hIL2 (vaccinia virus double-deleted human interleukin 2), in patients with advanced abdo...

Pittsburgh, PAPHASE118 participantsAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

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NCT07221552Recruiting

Evaluation of the PPAL

This research study is being conducted to better understand the impact of the PPAL assisted toileting device. The PPAL consists of a powered, height-adjustable commode chair with integrated transfer b...

Pittsburgh, PANA16 participantsAlicia Koontz

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About Multiple Sclerosis Clinical Trials in Pittsburgh

Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks the protective covering of nerve fibers, causing communication problems between the brain and body. Symptoms vary widely and can include vision problems, fatigue, and mobility issues. Disease-modifying therapies have significantly improved outcomes.

There are currently 11 multiple sclerosis clinical trials recruiting participants in Pittsburgh, PA. These studies are seeking a combined 14,192 participants. Research is being sponsored by University of Pittsburgh, Columbia University, Concure Oncology-Breast Microseed Inc. and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Sclerosis Clinical Trials in Pittsburgh — FAQ

Are there multiple sclerosis clinical trials in Pittsburgh?

Yes, there are 11 multiple sclerosis clinical trials currently recruiting in Pittsburgh, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Pittsburgh?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you about next steps.

Are clinical trials in Pittsburgh free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Pittsburgh studies also compensate for your time and travel.

What multiple sclerosis treatments are being tested?

The 11 active trials in Pittsburgh are testing new therapies including novel drugs, biologics, and treatment approaches for multiple sclerosis.

Data updated July 17, 2026 from ClinicalTrials.gov