Pittsburgh, PENNSYLVANIA14 Active Studies

Myalgic Encephalomyelitis Clinical Trials in Pittsburgh, PENNSYLVANIA

Find 14 actively recruiting myalgic encephalomyelitis clinical trials in Pittsburgh, PENNSYLVANIA. Connect with local research sites and explore new treatment options.

14
Active Trials
11
Sponsors
3,098
Enrolling

Recruiting Myalgic Encephalomyelitis Studies in Pittsburgh

RecruitingPittsburgh, PENNSYLVANIANCT06697301

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

The study is for patients with advanced melanoma who are eligible for standard therapy with Pembrolizumab....

740 participants
Eikon Therapeutics
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RecruitingPittsburgh, PENNSYLVANIANCT01760005

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

The purpose of this study is to assess the safety, tolerability, biomarker, cognitive and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by ...

490 participants
Washington University School of Medicine
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RecruitingPittsburgh, PENNSYLVANIANCT06351631

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bome...

400 participants
Merck Sharp & Dohme LLC
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RecruitingPittsburgh, PENNSYLVANIANCT06647498

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

The purpose of this research study is to test the study drug, referred to as remternetug, to determine its effectiveness for the study treatment of asymptomatic (at risk) Alzheimer disease in individu...

280 participants
Washington University School of Medicine
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RecruitingPittsburgh, PENNSYLVANIANCT05552157

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

The purpose is to evaluate the biomarker effect, safety, and tolerability of investigational study drugs in participants who are known to have an Alzheimer's disease (AD)-causing mutation. Stage 1 wil...

280 participants
Washington University School of Medicine
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RecruitingPittsburgh, PENNSYLVANIANCT05655312

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

In this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor (MC1R) is being evaluate...

264 participants
Perspective Therapeutics
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RecruitingPittsburgh, PENNSYLVANIANCT05877430

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Study CJB-101-01 will be conducted at multiple centers in the USA and Republic of Korea as an open-label safety and preliminary efficacy study of CJRB-101 in combination with pembrolizumab in subjects...

160 participants
CJ Bioscience, Inc.
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RecruitingPittsburgh, PENNSYLVANIANCT04419649

A Study of KER-050 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

The purpose of this study is to evaluate the effects of KER-050 on anemia in patients with very low, low or intermediate risk MDS....

140 participants
Takeda
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RecruitingPittsburgh, PENNSYLVANIANCT06049680

Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients

Evaluate the risk of developing EFAD and/or PNAC in adult and pediatric patients 1 month of age and older, who are anticipated to need 8 weeks or longer of parenteral nutrition treatment with SMOFlipi...

100 participants
Fresenius Kabi
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RecruitingPittsburgh, PENNSYLVANIANCT04139902

Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) Vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma

The purpose of this study is to test the effects of anti-PI-1 inhibitor (TSR-042) or anti-PD-1/anti-TIM-3 combination (TSR-042 / TSR-022) in patients with operable melanoma....

62 participants
Diwakar Davar
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RecruitingPittsburgh, PENNSYLVANIANCT06481592

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial cancer....

60 participants
Iovance Biotherapeutics, Inc.
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RecruitingPittsburgh, PENNSYLVANIANCT05361174

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC)....

53 participants
Iovance Biotherapeutics, Inc.
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RecruitingPittsburgh, PENNSYLVANIANCT02716246

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

The main objective of this study is to evaluate the efficacy and safety of UX111 for the treatment of MPS IIIA....

36 participants
Ultragenyx Pharmaceutical Inc
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RecruitingPittsburgh, PENNSYLVANIANCT05748873

Promising ROd-cone DYstrophy Gene therapY

This is a two-step, multicenter, Phase I/II study including an open-label dose-escalation phase (Step 1) and a three-arm, controlled, double-masked, randomized extension phase (Step 2), in subjects wi...

33 participants
SparingVision
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About Myalgic Encephalomyelitis Clinical Trials in Pittsburgh

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 14 myalgic encephalomyelitis clinical trials recruiting participants in Pittsburgh, PENNSYLVANIA. These studies are seeking a combined 3,098 participants. Research is being sponsored by Eikon Therapeutics, Washington University School of Medicine, Merck Sharp & Dohme LLC and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in Pittsburgh — FAQ

Are there myalgic encephalomyelitis clinical trials in Pittsburgh?

Yes, there are 14 myalgic encephalomyelitis clinical trials currently recruiting in Pittsburgh, PENNSYLVANIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Pittsburgh?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you about next steps.

Are clinical trials in Pittsburgh free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Pittsburgh studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 14 active trials in Pittsburgh are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated March 2, 2026 from ClinicalTrials.gov