Portland, OREGON16 Active Studies

Ankylosing Spondylitis Clinical Trials in Portland, OREGON

Find 16 actively recruiting ankylosing spondylitis clinical trials in Portland, OREGON. Connect with local research sites and explore new treatment options.

16
Active Trials
16
Sponsors
2,102
Enrolling

Recruiting Ankylosing Spondylitis Studies in Portland

RecruitingPortland, OREGONNCT06731478

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

This clinical trial is designed to assess the efficacy and safety of the triplet combination of trastuzumab deruxtecan (ENHERTU, T-DXd, DS-8201a) plus a fluoropyrimidine plus pembrolizumab versus stan...

726 participants
Daiichi Sankyo
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RecruitingPortland, OREGONNCT05867251

Study of AVZO-021 in Patients With Advanced Solid Tumors

This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients...

430 participants
Avenzo Therapeutics, Inc.
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RecruitingPortland, OREGONNCT06868290

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe active Granulomatosis with Polyangiitis (GPA) or Microscopic P...

126 participants
Novartis Pharmaceuticals
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RecruitingPortland, OREGONNCT05172726

Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis....

100 participants
Organon and Co
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RecruitingPortland, OREGONNCT06540963

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

The purpose of this study is to evaluate the investigational drug, tipifarnib (a pill taken by mouth), in combination with the Food and Drug Administration (FDA) approved drug, naxitimab, administered...

98 participants
Giselle Sholler
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RecruitingPortland, OREGONNCT05957367

A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies

This is a Phase 1/2, multicenter, open-label (unless otherwise specified in a combination-specific module) study of inlexisertib in combination with anticancer therapies. Modules within the master pro...

94 participants
Deciphera Pharmaceuticals, LLC
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RecruitingPortland, OREGONNCT06414954

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, a...

84 participants
NMD Pharma A/S
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RecruitingPortland, OREGONNCT03546686

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

The purpose of this study is to determine the impact of pre-operative cryoablation, and immune checkpoint inhibition (ICI) on on 3-year Event Free Survival (EFS), in women with residual hormone recept...

80 participants
University of Texas Southwestern Medical Center
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RecruitingPortland, OREGONNCT05386108

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain metastases from estrogen receptor (ER)-pos...

68 participants
Stemline Therapeutics, Inc.
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RecruitingPortland, OREGONNCT06840483

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

This is a global, multicenter, open-label study that aims to assess the efficacy and safety of zelenectide pevedotin in participants with NECTIN4-amplified recurrent, unresectable, or metastatic breas...

66 participants
BicycleTx Limited
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RecruitingPortland, OREGONNCT05772546

Avatrombopag vs. Placebo for CIT in GI Malignancies

The purpose of this study is to compare the efficacy of two study drugs, Avatrobopag versus placebo, to treat persistent Chemotherapy-Induced Thrombocytopenia (CIT) in patients with gastrointestinal (...

60 participants
Hanny Al-Samkari, MD
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RecruitingPortland, OREGONNCT06942572

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

This Phase 1/2 study will evaluate the safety, tolerability, and preliminary efficacy of subretinal SB-007 administration to determine dose selection in subjects with Stargardt's Type 1 (STGD1). This...

57 participants
Splice Bio
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RecruitingPortland, OREGONNCT06881992

A Phase 3 Study of Ersodetug in Patients With Tumor-Associated Hyperinsulinism

The objectives of this study are to evaluate the glycemic efficacy, safety, and tolerability of ersodetug for treatment of hypoglycemia in patients with Tumor-Associated Hyperinsulinism (tHI)....

48 participants
Rezolute
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RecruitingPortland, OREGONNCT06208748

SARC044: a Phase II Trial of Bezuclastinib in Combination with Sunitinib in Patients with GIST

This is an open label, single arm, phase 2 trial investigating bezuclastinib plus sunitinib in patients with GIST who have previously progressed on sunitinib....

40 participants
Sarcoma Alliance for Research through Collaboration
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RecruitingPortland, OREGONNCT06467344

Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)

This study is an open-label, single ascending dose clinical trial in participants who have ABCA4-related retinopathies. This is the first-in-human clinical trial in which ACDN-01 will be evaluated for...

13 participants
Ascidian Therapeutics, Inc
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RecruitingPortland, OREGONNCT06353997

Neoadjuvant INBRX-106 (Hexavalent OX40 Agonist) in Combination With Pembrolizumab as a Chemotherapy-sparing Regimen for Stage II TNBC (Triple Negative Breast Cancer) Patients

This is a Phase II trial to assess feasibility of pembrolizumab + INBRX-106 as a chemotherapy-sparing neoadjuvant therapy. One therapeutic arm is being evaluated to provide an informal comparison of p...

12 participants
Providence Health & Services
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About Ankylosing Spondylitis Clinical Trials in Portland

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 16 ankylosing spondylitis clinical trials recruiting participants in Portland, OREGON. These studies are seeking a combined 2,102 participants. Research is being sponsored by Daiichi Sankyo, Avenzo Therapeutics, Inc., Novartis Pharmaceuticals and 13 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Portland — FAQ

Are there ankylosing spondylitis clinical trials in Portland?

Yes, there are 16 ankylosing spondylitis clinical trials currently recruiting in Portland, OREGON. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Portland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Portland research site will contact you about next steps.

Are clinical trials in Portland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Portland studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 16 active trials in Portland are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov