12 HIV AIDS Clinical Trials in San Diego, CA (2026)

Q: How do I join a clinical trial in San Diego?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you.

Recruiting HIV AIDS Studies in San Diego

NCT07473778Recruiting

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

The goal of this observational study is to generate real-life information on the use of lenacapavir (LEN, YEZTUGO®, (YTG)) for pre-exposure prophylaxis (PrEP) across diverse clinical settings in the U...

San Diego, CA3,000 participantsGilead Sciences

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NCT07293559Recruiting

Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the stud...

San Diego, CA1,150 participantsInternational Maternal Pediatric Adolescent AIDS Clinical Trials Group

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NCT05241990Recruiting

Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

Despite availability of evidence-based alcohol reduction interventions (EBI), unhealthy alcohol use remains a barrier to HIV medication adherence, viral suppression and retention in HIV care and conse...

San Diego, CANA300 participantsJohns Hopkins University

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NCT06216600Recruiting

Women Focused Encounters for Resilience Independence Strength and Eudaimonia

The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to ...

San Diego, CANA300 participantsUniversity of California, San Diego

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NCT06848686Recruiting

Prevention Ambassadors: Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the...

San Diego, CANA210 participantsSan Diego State University

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NCT06263426Recruiting

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV....

San Diego, CANA200 participantsJohns Hopkins University

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NCT04883255Recruiting

Cannabis Use, Cognition, and the Endocannabinoid System in HIV

Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functio...

San Diego, CAEARLY_PHASE1138 participantsUniversity of California, San Diego

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NCT06856174Recruiting

Menopausal HT for Women Living With HIV (HoT)

Women living with HIV have been shown to experience more frequent and severe hot flashes and night sweats (collectively known as vasomotor symptoms) as compared to women living without HIV. This corre...

San Diego, CAPHASE4105 participantsAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

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NCT05514899Recruiting

Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV

This study has the potential to contribute to a more complete understanding of the independent and combined effects of cannabis use and HIV on the brain and on inflammation. Such knowledge may inform ...

San Diego, CAPHASE290 participantsUniversity of California, San Diego

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NCT05719441Recruiting

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

A5388 is a phase II, two-arm, randomized, double-blind, placebo-controlled study that will enroll 48 antiretroviral therapy (ART)-naïve adults with acute HIV infection (AHI) in order to determine whet...

San Diego, CAPHASE248 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06071767Recruiting

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

The purpose of this study is to evaluate the safety, tolerability, and efficacy of therapeutic vaccination with chimpanzee adenovirus ChAdOx1- and poxvirus modified vaccinia Ankara (MVA)-vectored cons...

San Diego, CAPHASE136 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06252402Recruiting

CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS

Human immunodeficiency virus type 1 (HIV-1) causes a persistent infection that ultimately leads to acquired immunodeficiency syndrome (AIDS). Treatment of HIV-1 infection with combination anti-retrovi...

San Diego, CAEARLY_PHASE115 participantsCity of Hope Medical Center

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About HIV AIDS Clinical Trials in San Diego

HIV (human immunodeficiency virus) attacks the immune system and, if untreated, can lead to AIDS (acquired immunodeficiency syndrome). Antiretroviral therapy (ART) can control the virus and prevent transmission. Research continues to pursue a functional cure, long-acting therapies, and preventive vaccines.

There are currently 12 hiv aids clinical trials recruiting participants in San Diego, CA. These studies are seeking a combined 5,592 participants. Research is being sponsored by Gilead Sciences, International Maternal Pediatric Adolescent AIDS Clinical Trials Group, Johns Hopkins University and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

HIV AIDS Clinical Trials in San Diego — FAQ

Are there hiv aids clinical trials in San Diego?

Yes, there are 12 hiv aids clinical trials currently recruiting in San Diego, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What hiv aids treatments are being tested?

The 12 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for hiv aids.

Data updated July 21, 2026 from ClinicalTrials.gov