36 Myalgic Encephalomyelitis Clinical Trials in San Diego, CA (2026)

Q: How do I join a clinical trial in San Diego?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you.

Recruiting Myalgic Encephalomyelitis Studies in San Diego

NCT03638583Recruiting

Alzheimer Prevention Trials (APT) Webstudy

The goal of the Alzheimer Prevention Trials (APT) Webstudy is to accelerate enrollment for Alzheimer's disease (AD) clinical trials by identifying and tracking individuals who may be at higher risk fo...

San Diego, CA200,000 participantsUniversity of Southern California

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NCT04262206Recruiting

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in com...

San Diego, CAPHASE420,000 participantsDuke University

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NCT05685745Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveri...

San Diego, CA5,000 participantsThe University of Texas Health Science Center, Houston

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NCT01429389Recruiting

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21....

San Diego, CA2,000 participantsSequenom, Inc.

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NCT06976203Recruiting

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease...

San Diego, CAPHASE3586 participantsBristol-Myers Squibb

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NCT07484217Recruiting

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal tr...

San Diego, CAPHASE3508 participantsAxsome Therapeutics, Inc.

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NCT07011745Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease....

San Diego, CAPHASE3426 participantsBristol-Myers Squibb

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NCT05702645Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment...

San Diego, CA330 participantsChildren's Oncology Group

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NCT06679855Recruiting

Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

The goal of this Phase 3, randomized, masked clinical trial is to is to find out whether milrinone, when given to infants after PDA closure, will help the heart work better by supplying oxygen to the ...

San Diego, CAPHASE3316 participantsNICHD Neonatal Research Network

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NCT04999904Recruiting

A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability

The ROCKY REHAB trial will provide a pragmatic approach to evaluate if incorporating a rocky, uneven terrain treadmill into the proprioceptive rehabilitation received during physical therapy can impro...

San Diego, CANA312 participantsHenry M. Jackson Foundation for the Advancement of Military Medicine

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NCT06887192Recruiting

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

ML-007C-MA-221 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ML-007C-MA in male and female participants aged 55 to 90 years with hallucination...

San Diego, CAPHASE2300 participantsMapLight Therapeutics

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NCT06734351Recruiting

A Study to Assess Safety and Effectiveness of Injections of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Change of Mid-Face Volume

Facial fullness is often regarded as a characteristic feature of a youthful face. Chronic reduction of collagen, elastin, and glycosaminoglycans contribute to the facial volume loss that characterizes...

San Diego, CAPHASE3231 participantsAbbVie

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NCT05960929Recruiting

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give I...

San Diego, CAPHASE3220 participantsONY

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NCT06184646Recruiting

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women....

San Diego, CANA200 participantsSan Diego State University

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NCT07108283Recruiting

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

Vitiligo is a long-term autoimmune condition that causes the skin to lose its color. The body's germ-fighting system (immune system) mistakenly attacks the skin cells (melanocytes) which produce the p...

San Diego, CAPHASE2200 participantsTakeda

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NCT07553637Recruiting

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD....

San Diego, CAPHASE2178 participantsAlto Neuroscience

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NCT07281079Recruiting

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

This Phase 3, randomized, double-blind, parallel-group (2-arm), placebo-controlled, multicenter study will evaluate the efficacy and safety of NNZ-2591 compared to placebo in pediatric participants wi...

San Diego, CAPHASE3160 participantsNeuren Pharmaceuticals Limited

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NCT06914609Recruiting

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

The purpose of this study is to evaluate the efficacy and safety of ION582 in children and adults with Angelman syndrome caused by a deletion or mutation of the UBE3A gene....

San Diego, CAPHASE3158 participantsIonis Pharmaceuticals, Inc.

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NCT06879041Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275....

San Diego, CAPHASE1136 participantsAstraZeneca

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NCT06366464Recruiting

A Study of Pitolisant in Patients With Prader-Willi Syndrome

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The ...

San Diego, CAPHASE3134 participantsHarmony Biosciences Management, Inc.

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NCT07535112Recruiting

A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

Researchers are looking for a better way to treat people who have advanced or metastatic colorectal cancer (CRC) with a specific mutation, the G12D mutation, in a protein called KRAS. Colorectal canc...

San Diego, CAPHASE1130 participantsBayer

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NCT05334368Recruiting

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

This is a 52-week, randomized, placebo-controlled, double-blind, parallel group, multicenter study of depemokimab in adults with uncontrolled HES receiving standard of care (SoC) therapy. The study w...

San Diego, CAPHASE3123 participantsGlaxoSmithKline

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NCT06859801Recruiting

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous...

San Diego, CA120 participantsSociety of Interventional Oncology

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NCT04696029Recruiting

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma....

San Diego, CAPHASE2118 participantsGiselle Sholler

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NCT06500481Recruiting

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

This phase III trial compares proton craniospinal irradiation (pCSI) to involved-field radiation therapy (IFRT) for the treatment of breast or non-small cell lung cancer that has spread from where it ...

San Diego, CAPHASE3115 participantsNRG Oncology

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NCT07002034Recruiting

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces depressive symptoms or depressive symptoms mixed with anxiety symptoms in participants with Adj...

San Diego, CAPHASE2100 participantsReunion Neuroscience Inc

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NCT07516119Recruiting

Predicting Pre-dementia

The goal of this observational study is to learn how well a multimodal "Progression and Risk" (PR) model can predict and stage early mild cognitive impairment (MCI) due to Alzheimer's disease in cogni...

San Diego, CA100 participantsPrevention Research Consortium Corp.

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NCT07332091Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-rel...

San Diego, CAPHASE284 participantsCSL Behring

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NCT06307795Recruiting

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

This is a Phase 1, first-in-human, open-label, multi-center study with the aim of exploring the safety, tolerability, PK, and preliminary anti-tumor activity of ANS014004 as a single agent in particip...

San Diego, CAPHASE163 participantsAvistone Biotechnology Co., Ltd.

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NCT06885554Recruiting

Adjustment Disorders in the US Military: Disease Trajectories and ADNM-20-Mil Validation

Adjustment disorders (AjDs) - a group of mental health diagnosis given following exposure to a stressor that results in preoccupation, failure to adapt, and/or functional impairments - have consistent...

San Diego, CANA60 participantsHenry M. Jackson Foundation for the Advancement of Military Medicine

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NCT06800833Recruiting

Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health

The objective of the proposed research is to determine the effects of fresh mango consumption on gut microbiome, and its relationship with skin health, sexual and mental health in relatively healthy a...

San Diego, CANA60 participantsSan Diego State University

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NCT05295433Recruiting

An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

The primary objective of this study is to evaluate the long-term safety of mRNA-3705 administered to participants with isolated methylmalonic acidemia (MMA) due to methylmalonyl-coenzyme A mutase (MUT...

San Diego, CAPHASE156 participantsModernaTX, Inc.

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NCT06430385Recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

The primary purpose of this study is to evaluate the safety and tolerability of ION440....

San Diego, CAPHASE148 participantsIonis Pharmaceuticals, Inc.

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NCT05279729Recruiting

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioe...

San Diego, CANA45 participantsSan Diego State University

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NCT07157787Recruiting

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

The primary objective of this study is to evaluate the efficacy of ALXN1920 compared with placebo in participants with PMN who are at a high risk for disease progression using 24-hour urine protein cr...

San Diego, CAPHASE230 participantsAlexion Pharmaceuticals, Inc.

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NCT05789056Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

To assess the safety, tolerability, and efficacy of QRX003 lotion (4%) when added to standard of care treatment regimen, including systemic therapy in subjects with Netherton syndrome...

San Diego, CAPHASE220 participantsQuoin Pharmaceuticals

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About Myalgic Encephalomyelitis Clinical Trials in San Diego

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 36 myalgic encephalomyelitis clinical trials recruiting participants in San Diego, CA. These studies are seeking a combined 232,667 participants. Research is being sponsored by University of Southern California, Duke University, The University of Texas Health Science Center, Houston and 28 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in San Diego — FAQ

Are there myalgic encephalomyelitis clinical trials in San Diego?

Yes, there are 36 myalgic encephalomyelitis clinical trials currently recruiting in San Diego, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 36 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated August 29, 2026 from ClinicalTrials.gov